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Presence of the Cdc42/Rac1 interactive binding (CRIB) motif alone as the dominant negative mutant of p21-activated kinase also inhibited the BNIP-2 effect. The present therapeutic possibilities - massive-dose vitamin D, aluminium hydroxide and supplementary Ca-intake, administration of active vitamin D metabolites - are discussed in the light of personal observations. Development, validation, and application of a novel 7-day Caco-2 cell culture system. Upregulated gene expression of local brain-derived neurotrophic factor and nerve growth factor after intracisternal administration of marrow stromal cells in rats with traumatic brain injury. Participants pressed a button upon entering a tunnel during virtual-reality roller coaster rides in downward or forward directions.

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A survey of the human factors discipline was conducted in the USSR. The percentage of positive reactions in the infarct group decreased sharply after the first 24 hours. Chronic pelvic pain caused by residual ovaries and ovarian remnants. In method 1, the classic O2 Fick equation is expressed in terms of oxygen uptake (VO2), arterial pulse (SaO2) and venous oximetry (SVO2) saturations. The practice-plus-informative-feedback groups (right-wrong, nothing-wrong, and right-nothing) discovered the concepts faster than the active training group.

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Etoposide-based combination chemotherapy in malignant histiocytosis. The EBV genome was detected in the HCL-O cells but not in the original cells. Methoxypsoralen compounds in combination with ultraviolet light are effective in preventing proliferation of bladder carcinoma cells in vitro. A survey of women who had received HRT found that media reports on the WHI study had a significant influence on their use of HRT.

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Statistically significant monocyte migration was observed within 60 min of chemokine addition to the basal surface of the endothelium and an asymmetric distribution of MCP-1 across the monolayer was observed at all time-points. In another group of 15 patients endoscopy performed 2 months after the operation revealed that 93 per cent of the ulcers were healed. Observations on some immune properties of preimplantation rat blastocysts. However, this nuclide showed a high concentration in viable tumor tissue, less in connective tissue (containing inflammatory tissue), and was not seen in necrotic tumor tissue regardless of the time after administration of 201Tl(I)-chloride. Effect of heparin and amben on blood coagulation activity in experimental acute ischemia of the extremities

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An ultrastructural study of the craniocaudal continuation of the glycogen body. Changing the vertical dimension by grinding of the waxed occlusal surfaces The immobilization effect was most profound in the femora as the cortical thickness and the femur score were significantly higher than those in the mobile femora. Atrial pacing has been recently re-evaluated as a stress test for the detection of coronary artery disease.

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Tuberculous basal meningitis with multiple cranial nerve palsies and leprosy. Use of lactic-acid bacteria in the prevention and treatment of suppurative-inflammatory diseases in pregnant women and puerperae

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The psychosomatic approach to dentistry for patients with handicapping conditions. Withdrawal of feeding-tubes from incompetent patients: the Terri Schiavo case raises new issues regarding who decides in end-of-life decision making. The study of intravascular volume using the 51Cr-labeled red blood cell method indicated that severe vascular occlusion occurs in the tumor after hyperthermia.

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A second cohort of 423 transplant recipients was independently analyzed for the genotype associations identified in the first cohort. Liver transplantation (LT) for polycystic liver disease (PLD) has evolved to be an option for treating these patients. This disease is important to the physician because recognition of these cutaneous lesions may allow early diagnosis of internal neoplasia. It is concluded that anal pain or discomfort, pruritus ani and faecal soiling are common symptoms of uncomplicated haemorrhoids and that they are abolished in the majority of patients by successful treatment for rectal bleeding and haemorrhoidal prolapse. The aim of the study was to assess the effect of the time of ingestion of a meal on the pharmacokinetics and pharmacodynamics of a levodopa/carbidopa controlled-release formulation in parkinsonian patients on chronic levodopa therapy.

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Altered accumulation of zinc by aging human fibroblasts in culture. With respect to the binding of these proteins, ionic and/or hydrophobic interactions were no longer negligible during the chromatographic process and the retention of the macromolecules by the stationary phase depended on the elution conditions (ionic strength, pH, etc.). Alterations in brain and pituitary beta-endorphin content in genetically epilepsy-prone rats. In most vertebrates, the segmentation of the paraxial mesoderm involves the formation of metameric units called somites through a mesenchymal-epithelial transition. Evidence for altered catecholamine metabolism in polycystic ovary syndrome.

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A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Acute treatment with clonidine or calcium entry blockers on opioid withdrawal in guinea-pig ileum. A human protein S cDNA was used as a hybridization probe to analyze a panel of somatic cell hybrids containing different human chromosomes. Methods for reducing the risks of cross-contamination in catering premises are discussed. The influence of light infestations of Linognathus vituli on the growth of young cattle.

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We developed an interactive budget impact model to evaluate the potential economic implications of Medicare payment changes to large dialysis organizations treating patients with ESRD who are receiving phosphate binders. Stimulation with a pure, continuous and defined tone yielded cochlear microphonics that can be interpreted easily.

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The long-term efficacy and safety of a third-generation implantable cardioverter-defibrillator implanted with thoracotomy and nonthoracotomy lead systems was evaluated in a multicenter international study. The incubation of murine spleen cells in the lymphokine interleukin 2 (IL 2) gives rise to lymphokine-activated killer (LAK) cells capable of lysing fresh tumor cells in short-term lytic assays. Three of the films are green light-sensitized for use in combination with green light-emitting rare-earth screens. New strategies for overcoming limitations of mesenchymal stem cell-based immune modulation. Salicylate-induced injury of pyruvate-kinase-deficient erythrocytes.

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To examine the test characteristics of immunofluorescence (IF) and enzyme-linked immunosorbent assays (ELISA) in a consecutive series of patients under evaluation for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). This linear peptide inhibited thrombin, with an IC50 of 9.0 microgram/mL. Dose-response curves for amiloride and spironolactone were defined in 15 hypertensive patients treated with bendroflumethiazide (bendrofluazide). The success of any total knee arthroplasty (TKA) is influenced by a complex interaction between component geometry and the surrounding soft tissues.

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We examined the phenotypical expression of PMN beta(2M)-integrins (CD ll a, CDll b, CD 11c) in a group of 19 subjects with leg DVT. Although it appears that better local control rates can be achieved, additional phase II/III studies are needed. Single intracisternal administration of bisphenol-A (20 microg) into 5-day-old male Wistar rats did not cause any significant changes in habituation, as assessed in terms of locomotor activity, rearing, sniffing and grooming in rats at 8 weeks of age. Cross-sectional areas of the suprahepatic IVC and descending aorta were measured on a single axial steady-state free-precession (SSFP) image at the level of the esophageal hiatus in end-systole.