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The RET protooncogene in sporadic pheochromocytomas: frequent MEN 2-like mutations and new molecular defects. The former display a well defined network of long thin channels of granular endoplasmic reticulum situated mainly around the glycogen clusters. Endothelial function in the proximal and mid-descending aortic regions was studied using a myograph technique. In this report we describe yearly changes in pneumoconiosis patients and pneumoconiosis progression in each industry in Japan, using statistics of Ministry of Labour based on the results of pneumoconiosis examinations performed at plants in accordance with the Pneumoconiosis Law.

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Intrapulmonary CGRP-containing nerve fibres, including those innervating NEBs, always appeared to belong to a nerve fibre population different from the DiI-traced fibres and hence did not arise from the nodose ganglion. Tetanic stimulation of the fimbria at rates which eliminate this interneuronal response in the lateral septum, produce an irregular pattern of firing in medial septal neurones which previously exhibited a synchronized bursting discharge to single pulses. This technique is useful in identifying antigens in tissues where insufficient unstained material is available. Further, peripheral blood monocytes from either skin-test-positive or skin-test-negative donors significantly decreased the in vitro growth of C. albopictus to the presence of coffee in its habitats during the early phases of its life cycle.

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The histological findings of the skin reaction to TAS-1D3 were similar to those of the reaction to PPD. Optical coherence tomography (OCT) allows quantification of retinal structures, such as the retinal nerve fiber layer (RNFL) thickness, at the optic disc and the ganglion cell layer (GCL) at the macula, on a micrometer scale. Under a highly humid atmosphere, on the other hand, T(beta) was formed at 90 degrees C directly as a result of T(h) dehydration.

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Little attention has been paid, however, to the effects of strength training on the other components of motor performance. The part played by some testicular steroids in the control of spermatogenesis is discussed. The orientation angle obtained with the Gaussian and box filters is largely independent of the filter width and the Schmidt number.

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Ten clones were not significantly represented in normal leukocytes and spleen mRNA. Statistically significant differences in calcium, inorganic and organic phosphorus, magnesium, fluoride and carbohydrate were observed between free smooth-surface and approximal plaque. Despite equal titers of V3 loop specific binding antibodies in sera from both groups of animals, neutralization of ADA by sera from gp140-immunized animals was insensitive to the presence of ADA-V3 peptide, whereas addition of this peptide to sera from gp120- immunized animals blocked all detectable neutralizing activity against ADA.

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This prospective clinical trial was designed to assess the ability of the mammary stimulation test to predict preterm birth in a private nulliparous population. The results are of particular clinical interest: with an increased rate of bone ingrowth, weight bearing might be allowed much earlier, thus reducing the recuperation period. BRAF V600E and TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrence. In conclusion, plasticity of the ENS is a feature of intestinal inflammation.

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Adoptive transfer studies indicated that memory cells migrated through the bone marrow and divided there preferentially. Relationship between interpregnancy interval and cervical length in high-risk women.

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On multivariate analysis the MLN size remained independently significant in terms of overall and disease-free survival rates, and the UICC N stage was not significant, independently of the n group. In contrast to most cases, our patient was not growth retarded despite severe delays in psychomotor development. It is therefore suggested that both types of response are governed by a single regulatory mechanism.

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Ultrastructural study of the interaction between Acholeplasma laidlawii and antibody. Pairwise sequence comparisons were made for 6 farnesyl diphosphate synthases, 6 geranylgeranyl diphosphate synthases, and a hexaprenyl diphosphate synthase.

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Vaccination of Lewis rats with temperature-sensitive mutants of Mycoplasma pulmonis: adoptive transfer of immunity by spleen cells but not by sera. All have linear chromosomes whose lengths range from 935 to 955 kbp, and all contain multiple linear plasmids in the 16- to 175-kbp size range. The effects of Mycoplasma hyorhinis and of Mycoplasma hyopneumoniae on pig kidney primary tissue culture. For the field experiment, the method was applied using the measured concentrations of individual sampling points, the depth-integrated concentrations, the area-integrated concentrations, and the effluent concentrations of the cell. Updating on the subject of oral antibiotic treatment with cephaloporins

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Both cytoplasmic and nuclear populations of H-ferritin contain mixtures of non- and O-glycosylated forms, but the nuclear population is enriched in O-glycosylated forms. Contribution of quantitative radio-scintigraphy to diagnosis of wrist injuries undetected on plain films: a prospective study of 154 cases Plaque stabilization is a new concept encompassing many functional and morphological factors that are influenced in the short and long term by aggressive lipid lowering. However, those in the rapid group showed delayed peaks at days 24 or 38. The mixture of substances in the photochemical smog could be detected by different reduction rates of exposed bacteria.

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During a period of 12 months, 88 patients with severe haemorrhage from gastric or duodenal ulcers or from erosive gastritis completed a double-blind trial of either cimetidine or placebo. An evaluation was made of the possible relation between renal thromboxane (Tx)A2 synthesis (measured as urinary excretion of TxB2) and the loss of glomerular permeability to proteins, in 5 children with seven episodes of minimal change nephrotic syndrome. TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. Cytochemical detection of carbohydrates in the Golgi complex of Leptomonas pessoai.

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To test this hypothesis, it is necessary first to estimate the incidence of morbidity for both standard and conformal fields. We report here that the WK-HA strain (hyperactive but not hypertensive) exhibited the hyperreactivity characteristic of SHRs, and not the WK-HT strain (hypertensive but not hyperactive). Preliminary study of an increase of a plasma apolipoprotein E variant associated with peripheral nerve damage.

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Other controversial areas relate to a lack of a consensus definition of hypertension among hemodialysis patients, uncertainty in the definition and assessment of volume excess, and the lack of adequately powered randomized trials to evaluate the level to which BP can be lowered in those on dialysis. In 14 cases out of the 31 presence of a small number of Sternberg-Reed (SR) cells has been revealed and the diagnosis of Hodgkin disease (Hk) was made. PEPI/LVETI ratio and ejection fraction were also abnormal in other patients with constrictive pericarditis when compared to normal subjects. It was showed that the 464 cm-1 peak arising from the quartz grains in the veins near the fault plane shifts by 3. To evaluate the specificity of this requirement, we examined the functional capacity of CD2 to activate the PI pathway in a TCR-deficient cell which had been transfected with a heterologous receptor, the human muscarinic subtype 1 receptor (HM1).

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Patients who attained a remission quickly or in whom leukemic cells in blood and bone marrow were rapidly cleared had long remissions. Comparison between inhaled and oral corticosteroids in patients with chronic asthma. Remarkably, a quantitative effect of the heavy chain Met-265 oxidation on relative binding capacity was only detected for doubly oxidized IgG1, whereas IgG1 with only one oxidized heavy chain Met-265 was not found to significantly affect IgG1 binding to huFcRn.

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These included improper sanitary techniques, ta tatau being performed in unlicensed premises by temporary tattooists, patients that were unwilling to access medical services due to the expectations of tradition, lack of follow-up and lack of infection advice by the tattooist. Polymorphonuclear leukocytes (PMN) isolated from the oral cavity of healthy human volunteers, spontaneously generated superoxide, nitric oxide (NO) and other reactive oxygen species (ROS) which exhibited strong luminol chemiluminescence (LCL). We present results from our own laboratories, in which we compared these immunoprobes in selected experimental situations. The progeny of these hens had anomalies manifested by bilaternal medial deviation of the toes, exophthalmia, and shortened femurs.

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In order to determine the minimal numbers of placental-fetal units required to maintain pregnancy and mammary gland growth, fetuses and placentas were removed on day 12 of pregnancy in addition to the pituitary so that only one fetus and one placenta remained in the uterus of a group of 6 rats with other groups having 2, 3, 4, 5 remaining. Current treatments vary from immobilization to extensive reconstructive surgical interventions. In this study, affective, cognitive, behavioral, and demographic contrasts were conducted. The effects of substantia nigra (SN) stimulation on the activity of the nucleus ventralis lateralis of the thalamus (VL) have been studied.

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Methods and measures in the rehabilitation and social integration of rheumatic patients in old age Gene diagnostics provide new insights into breast cancer prognosis and therapy. Trace metal concentrations and their transfer from sediment to leaves of four common aquatic macrophytes. When homogenates of control cells were fractionated on Percoll gradients glucocerebrosidase, like beta-hexosaminidase, was distributed in two peaks, one at low density and one at high density.

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The surfaces of these a-Se colloids could be coated with conformal and smooth shells made of Pt and SiO2. The objective of the present study was to assess the mid-term results of paravalvular leakage closure with this device. Exceptions to this predominant trajectory were found in the case of some of the axons which entered the ventral blade of the rostral fascia dentata, and coursed laterally from their point of entry.

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A practical challenge is to design the volumetric scout acquisition and processing steps to provide good image quality (at least good enough to enable 3D organ segmentation) while delivering a radiation dose similar to that of the conventional 2D scout. Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. Dependence was associated with background craving and smoking, but did not predict change in craving across the entire sample for any cue. Upon reinstatement of toluene, it was readily degraded without a significant lag period, even after a starvation period of 130 days. In both men and women, the ages for the onset and completion of puberty were also normal.

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Five out of 300 patients with bronchogenic carcinoma referred for pre-operative radioisotope imaging showed perfusion losses markedly in excess of regional ventilation impairment, a finding previously reported as being typical for pulmonary thrombeembolism. However, during the course of a radiotherapeutic treatment a transitory increase of 13NH3 uptake could be observed. Hypomethylated state of estrogen receptor gene in endometrial carcinomas. The purpose of this review article is to summarize information available on collagen dosage forms for drug delivery as well as to impart an overview of the chemical structures and the galenical properties including detailed description of the processing steps - extraction, purification, chemical crosslinking and sterilization.

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Angiography within 1 h of the onset of an intracerebral haematoma in a hypertension man showed active bleeding from at least two lenticulostriate arteries. The glycobiology of the CD system: a dictionary for translating marker designations into glycan/lectin structure and function.

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These data suggest that dopamine increases cyclic AMP levels by activating predominantly beta-adrenergic receptors and partly dopamine receptors in the canine myocardium, kidney and superior mesenteric artery. were divided into four groups on the basis of their reading ages. The electrocardiographic and vectorcardiographic criteria applied in order to assess the involvement of the dorsal wall have been those suggested by Perloff and by Hoffman and coll. In order to facilitate further molecular and functional characterization of this molecule we have established a T-T hybridoma cell line which stably expresses RT6.2. Host cells were detected by interphase cytogenetics in all patients posttransplant, at times varying from 28-1,825 days, whereas routine analysis detected host cells in only 4 patients, 3 of whom were found to be in relapse.

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Dermabrasion under regional anesthesia without refrigeration of the skin. A new cell surface, detergent-insoluble glycoprotein matrix of human and hamster fibroblasts. Escherichia coli producing CNF1 and CNF2 cytotoxins in animals with different disorders. In the context of health care reform, a new strategy is introduced that reverses present trends and incentives, called managed outcomes. In phase 2, midazolam (0.2 mg kg(-1)) with 1 mg kg(-1) of either racemic ketamine (group K) or S-ketamine (group S) was injected and followed by a continuous infusion (1 mg kg minute(-1)) of each respective drug.

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A strain of Saccharomyces cerevisiae lacking the GPD2 gene, encoding one of the glycerol-3-phosphate dehydrogenases, grows slowly under anaerobic conditions, due to reductive stress caused by the accumulation of cytoplasmic NADH. We demonstrate that the expression of the small heat shock protein alpha B-crystallin (but not other heat shock proteins or apoptosis-regulating proteins) correlates with TRAIL resistance in a panel of human cancer cell lines. Lymphocyte subpopulations in peripheral blood of patients with non-Hodgkin lymphoma. Such measurements are difficult to perform in soft tissues because transverse-mode ultrasonic waves are very highly attenuated by the tissue. Role and regulation of iron-sulfur cluster biosynthesis genes in Shigella flexneri virulence.

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Positive as well as some negative micro-organisms were seen within the colony. The spermine content in the brain during oxygen convulsions decreased as well, but four hours after decompression it increased significantly not eaching the control level.

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Saccharomyces cerevisiae is a potential host system with significant closeness to higher eukaryotes and provides opportunity for attempts to express membrane proteins. Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis. The effect of N,N-dimethyloctylamine on the enantioselectivity for some fentiazine derivatives, observed with immobilized AGP, was equal to that obtained with AGP as a chiral complexing agent in the mobile phase.

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Due to the role of alginate in pathogenesis as well as its unique material properties harnessed in numerous applications, results obtained in this study will aid the design and development of inhibitory drugs as well as the commercial bacterial production of tailor-made alginates. during the mating period (3rd decade of March) and in the final phase of active life (1st decade of September). This chromophore composition suggests that the blue light photoreceptor may initiate signal transduction by a novel pathway which involves electron transfer. Acute onset or exacerbation of rubeosis iridis associated with peripheral retinal detachment after vitrectomy represents a rare but serious complication of advanced diabetic retinopathy that indicates a poor prognosis.

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The authors analyse the results which emerged from a long-term follow-up of 15 patients affected with lesions of the discoid meniscus treated arthroscopically, by expressing both a subjective and an objective evaluation and emphasizing several details concerning the surgical method used. (2005) demonstrate that a heart-specific knockout of one SR protein, ASF/SF2, produces cardiomyopathy and misregulation of specific alternative splicing events during early postnatal development. salivarius could no longer be isolated after seven days of the drug administration. The availability of the gene encoding the Hib P2 protein should facilitate investigation of both the immunogenicity and the structure-function relationship(s) of this major outer membrane protein. Blockade of the renin-angiotensin system as a therapeutical basis.

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The extended anterior subcranial approach differs significantly from more traditional surgical approaches to the skull base in that it allows a broad inferior access to the anterior skull base planes with tumor exposure from below rather than via the transfrontal route. The combination of intranasal interferon and ipratropium with oral naproxen gave promising results in experimental rhinovirus inoculation.