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STAT3 does not bind directly to promoter DNA, but is recruited by C/EBPbeta. We describe a patient with long-standing sarcoidosis who developed multiple cystic cavities mainly in the upper lobes. Renal disease may increase apparent phenytoin in serum as measured by enzyme-multiplied immunoassay.

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Foreperiod is the interval between presentation of warning and response cues. These figures were used to derive signal-to-noise ratio (SNR) descriptors of the system performance. An outbreak of Shigella sonnei infection due to contamination of a municipal water supply in northern Israel.

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In the DRG ipsilateral to the BV injection, significant increase of mRNA levels of 5-HT(1A), 5-HT(1B), 5-HT(2A) and 5-HT(3) receptor subtypes were observed at 1 and 4h after the BV injection, while increase of 5-HT(2C), 5-HT(4), 5-HT(6) and 5-HT(7) receptor subtype mRNAs was detected at 4h only. Three-dimensional structure of the crystalline surface layer from Aeromonas hydrophila. A hospital-based comparative study of the knowledge, attitudes and practices of family planning among women belonging to different socio-economic status. Diagnostic laparoscopy with identification of visually normal pelvic peritoneum before euthanasia, followed by laparotomy with excision of a large area (at least 4 x 6 cm or 24 cm2 per animal, 408 cm2 surface in all baboons) of this visually normal-appearing peritoneum.

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Colostral T lymphocytes detected by intracytoplasmic and membrane markers. Amalgam was not found to be related to lower secondary caries progression in dentine compared to composite-based materials after 8 weeks in situ. Differential protein expression was screened by difference gel electrophoresis and 2-D SDS-PAGE.

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There was no significant difference in the frequency of mid-term redissection between the two groups. For the evaluation of the texture characteristics of the AFM images, statistical surface morphological and fractal analytical methodologies and Minkowski functionals were used. A comparison of spinal ligaments--differences between bipeds and quadrupeds. In contrast, RAP genes do not suppress phenotypes in the yeast Saccharomyces cerevisiae that are deficient in RAS. Linkage disequilibrium analyses within chromosome 19p in multiple sclerosis.

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The inhibitory effect of both glycosaminoglycans on the formation of C3b,Bb in the presence of nP or aP was less when the number of C3b sites per target cell was increased. Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. The biopsy, however, revealed proliferation of fibroblasts and fibrocytes with neither prominent atypia nor mitosis in a myxoid matrix.

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Recently it has been reported that allicin (diallyl thiosulphinate), an antibacterial principle of garlic, can inhibit bacteria adherence and prevent biofilm formation in vitro. Direct adrenergic stimulation of the release of thyrotropin and its subunits from the thyrotrope in vitro. Although there was no significant difference of cellular infiltrates in the lesional skin between ADe and ADi patients, ADe had significantly increased tissue eosinophilia than ADi. The stabilization of the C3b molecule in immune deposits by formalin. Characterization of two clinical, multiple-drug-resistant isolates of Enterobacter cloacae.

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A comparison of engine polishing and toothbrushing in minimizing dental plaque reaccumulation. Recently, additional studies comparing laparoscopic versus open surgery for gastric GISTs have been published, and an updated meta-analysis of this subject is necessary. Effect of the addition of albumin on the preservation of hemoglobin solutions lyophilized in the presence of glucose In these patients, the risk of placing the CHG disk may present more risk than using alternative antimicrobial dressings.

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Acid glycohydrolase in Chinese hamster with spontaneous diabetes II. In all homonuclear correlation, the most intense peaks are represented by the diagonal. Performance with cube-like figures was unaffected by the number of corner junctions present, though performance was affected when the corners did not configure into a cube. Characterization of the interaction of bovine plasmin with Streptococcus uberis. Patients of HMD with type-A color vision defects (CVD) had primarily a reduction of b-wave amplitudes in the full spectrum of 480-620 nm, and patients with type-I CVD a reduction of b-wave amplitudes wave-lengths of 480-560 nm.

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An experimental determination of the strains acting on femoral components of hip implants embedded in bone cement was made for the case of (a) porous surface coated and (b) conventional uncoated implants. Therefore, proteases induce erythroid differentiation in these cells by acting proteolytically on a substrate(s) that is exterior to the cell. None of these anomalies can be regarded as primary, but they are likely to be selected because they confer a slight selective advantage for the carrier cells during the tumoral progression. Thirty-six patients with locally advanced disease and no prior exposure to anthracyclines received the following regimen: epirubicin (Farmorubicin) 30 mg/mq and mitoxantrone (Onkotrone/Novantrone) 10 mg/mq by IAC short infusion on day 1, every 3 weeks for up to six cycles.

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Redox reactions occurring during secondary ion mass spectrometry of some heteroanthracycline antitumor antibiotic precursors. In the present article we describe experimental procedures able to eradicate, in vitro, by using specific immunological reagent, MDR tumor cells. In the other, the patient died of spontaneous rupture of the innominate artery in the early postoperative course after operation for aneurysm of the celiac artery. The identification of a specific clinical-EEG pattern provides a useful tool for the epileptogenic zone localization in non-invasive pre-surgical assessment of patients with hippocampal sclerosis.

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Since degradation of tumor tRNA appears to be delayed, the excessive amounts of the urinary methylated nucleosides must be derived from RNA in nonneoplastic tissue. Isolation of Pasteurella multocida from sporadic outbreaks of bovine pasteurellosis in Assam. CT-proved focal and diffuse changes of the pleura and the chest wall in 36 patients underwent HR-MRI, and visual comparison of MRI and CT was done retrospectively.

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This clinical method compares favourably with a modification of the articular index described by the Cooperating Clinics of North America. This article outlines some of the problems that are likely to be encountered in such situations and provides seven recommendations that should improve the memorability and comprehensibility of briefing sessions. Expression of granulocytic functions by leukemic promyelocytic HL-60 cells: differential induction by dimethylsulfoxide and retinoic acid.

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Butyrate, a low-molecular weight four-carbon chain volatile fatty acid (VFA) has been previously shown to withdraw cells from cell cycle or to promote cell differentiation, and finally to induce programmed cell death. Jejunal resection and anastomosis resulted in complete resolution of the bleeding, and the patient has experienced no recurrent bleeding over a 4 year follow-up period. Many of these deaths can be prevented by prompt action to provide basic cardiopulmonary resuscitation (CPR) and early defibrillation. This study provides biochemical and morphologic evidence that glutamine deprivation induces apoptosis in rat intestinal epithelial cells. Does prior acute exercise affect postexercise substrate oxidation in response to a high carbohydrate meal?

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Although the morphology of the lesions in MSSE is similar to classical actinic keratoacanthoma (KA), several distinctive features in clinical presentation and histology have been emphasized. The following categories of leukemia cutis are discussed in this article: myelogenous (granulocytic) leukemia, monocytic leukemia, myelomonocytic leukemia, lymphocytic and lymphoblastic leukemia, hairy cell leukemia, and adult T-cell leukemia/lymphoma. The control group of 3 patients received c-MI at 10 mg/m(2) every 28 days.

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The resolution of these issues depends almost entirely on the specification of the question of interest. We suggest that the increase in lipogenesis in the liver of continuously irradiated rats is an important factor in lipid metabolism disorders caused by the continuous irradiation. To study the physiological roles of endogenous opioid peptides in drinking and feeding behaviors, the effects of water deprivation and fasting on plasma immunoreactive (IR) beta-endorphin (beta-end), IR-Antidiuretic hormone (ADH) and IR-Prolactin (Prl), pituitary IR-beta-end and IR-methionine-enkephalin (IR-Met-enk) and IR-ADH, and hypothalamic IR-beta-end and IR-Met-enk were observed in rats.

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There was a significant decrease in the rate of back platelet uptake of 3H-serotonin and an increase in the sensitivity of serotonin receptors to serotonin in the patients before therapy and normalization of these parameters after therapy. This experience of magnetic resonance scanning has shown that it is superior to computed tomography in showing the extent of malignant disease and, provided the correct pulse sequences are employed, it is always possible to distinguish tumour from retained secretion or inflamed mucosa. Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs. Supratip convexities following rhinoplasty present a challenge to the surgeon.

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In pregnancies following clomiphene treatment, close supervision is imperative as soon as pregnancy is evident. As early as 4 days after arthritis induction, the hepatic mRNA levels of beta-fibrinogen, alpha 1-AGP and albumin were distinctly different from control values. These findings suggest that phosphorylation serves to regulate c-Myb activity and that loss of this phosphorylation site from the v-Myb proteins may contribute to their transforming potential. We propose that AS1-AS2 complexes interact to create a loop in the KNOX promoter and, likely through recruitment of HIRA, form a repressive chromatin state that blocks enhancer activity during organogenesis. When compared with the known circulating hantaviruses in the Netherlands, Puumala (PUUV) and Tula (TULV), SEOV causes a more severe form of HFRS.

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The effects of nicorandil and nifedipine on ischemia--reperfusion-induced myocardial infarct size following a 2-h occlusion and 30-min reperfusion period of the left anterior descending coronary artery (LAD) were compared in anesthetized dogs. Sulfotransferases I, II, and III--which sulfate glucocorticoids--were used in this comparison.

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In all of the families examined we were able to distinguish the affected vs unaffected (not at risk) members. The action of Ca was restricted to cathodal pulses, whereas La decreased the permeability of both the hyper-and depolarized membrane. slight lateral rotation of the kidneys, more pronounced on the right side, c.

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This assignment is consistent with the segregation pattern of the 93 hybrid clones analysed. Here, we aimed to examine the association in patients wtith stroke and community-based healthy controls. Visualization of yellow mucopurulent endocervical secretions on a white swab and the presence of 10 or more polymorphonuclear leukocytes per microscopical field (at a magnification of 1000) in satisfactory gram-stained endocervical smears were independently correlated with cervical Chlamydia trachomatis infection. Attachment of bacteria to tonsillar epithelium during acute tonsillitis. Quantitative assessment of the effect of chronic phrenicotomy on the induction of the crossed phrenic phenomenon.

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We used high-resolution MRI and surface-based, computational image analytic techniques to map regional brain size and grey-matter abnormalities at the cortical surface in a group of 27 children and adolescents with attention-deficit hyperactivity disorder and 46 controls, who were group-matched by age and sex. Effects of nervous mutation on Purkinje cell compartments defined by Zebrin II and 9-O-acetylated gangliosides expression. A modification of the Favaloro sternal retractor is described that allows a singel person to operate the apparatus when elevating the sternal plate. Neither BMP nor BMIM degraded in any test, suggesting that these ILs are unlikely to be removed by traditional treatment.

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Twenty-four and 48 hours after pseudomonas challenge each animal received granulocyte transfusions. In patients without systemic diseases, the serum level of sIL-2R was significantly and positively correlated with the urinary excretion of protein, and the serum levels of creatinine and uric acid, and was negatively correlated with the glomerular filtration rate (GFR). The peripheral lamina of rat liver nuclei is characterized by the presence of three major polypeptides called lamins A, B, and C.

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An empirical study of 8,000 males, in which 43 body proportions were measured, shows that unexpected disturbances occur in the extreme values of an otherwise symetrical distribution curve when more than two traits are combined. IgE binding to proteins, corresponding to the major birch pollen allergen Bet v 1 and to Bet v 2 (birch pollen profilin) could be observed. Furthermore, residents with indicators of problems presented significantly lower social skills means than those of residents without indicators of burnout, anxiety, or depression. The results indicate that oral status was related to well-being status. Increased operator productivity is a desired outcome of user-CAD interaction scenarios.

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Paraformaldehyde-fixed vibratome sections of brains and cryostat sections of peripheral lymph nodes were studied of rats treated with endotoxin (2.5 micrograms/kg or 2.5 mg/kg i.v.), rats infected with rabies virus, and rats exposed to experimental allergic encephalomyelitis (EAE). Host defence mediates interspecific competition in ectoparasites. Dermatosparaxis, a genetic disease, results from the deficiency of the NH2 procollagen peptidase, an enzyme which removes the NH2-terminal nontriple-helical extensions from procollagen.

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This report describes injuries occurring in the Northridge earthquake which resulted in death or hospital admission. These results indicate that 5-azacytidine treatment resulted in a stable alteration in the capacity of T984-15 cells to differentiate and suggests that the loss of myogenic potential may have occurred as a result of an epigenetic phenomenon rather than a somatic mutational event. Flux through the arginine biosynthetic pathway of Neurospora crassa was measured under a variety of physiological conditions. The time between primary and revision surgery varied between 5 and 54 months. Furcate placentae (with separated umbilical vessels) had statistically greater than normal volumes of villi, villous trophoblast, and syncytial knots.

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Platelet activating factor: an inhibitor of neutrophil activation? Usually it is related to ulcerative nonspecific colitis or Crohn disease. Developmental changes in cell surface and cytoskeletal elements have been studied in human promyelocytic leukemia cels (line HL-60) which differentiate into functionally mature myeloid cells when grown in dimethyl sulfoxide (DMSO)-supplemented medium. The metabolism of 4-androstene-3,17-dione by liver microsomes from the juvenile rainbow trout, Salmo gairdnerii, was studied in vitro.

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The interaction of EerI with the p97 complex appears to negatively influence a deubiquitinating process that is mediated by p97-associated deubiquitinating enzymes. We provide a review of the use of DOACs in the older frail population from both hematological and geriatric perspectives, as well as propose an algorithm for how these agents may be used in this frail population. Direct interaction of proteoglycan macrophage colony-stimulating factor and basic fibroblast growth factor. Homologous antisera were raised against lipopolysaccharides (LPSs) isolated from pyocin 103-sensitive JW31 strain Neisseria gonorrhoeae and its isogenic, pyocin-resistant variant, JW31R. Beta adrenergic activity contributes to the maintenance of elevated circulating levels of glucose, free fatty acids and total ketones in experimental DKA but not to the elevated plasma levels of the prostaglandin derivatives.

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We conducted a nested case-control study within a previously defined cardiovascular cohort of elderly Quebec patients using linked administrative health databases. The effects of total parenteral nutrition (TPN) on experimental acute and chronic renal failure were studied with special reference to age in the rat. Fever and leukocytosis are occasionally observed in patients with psychiatric disorders.

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This includes the accumulation of major sperm protein (MSP) transcripts in germ cells, a phenotype that is suppressed by feminization of the germline. Furthermore, the functional properties of anti-V8-protease antibodies were analyzed in vitro. Canavanine arrests a critical function in head morphogenesis and the potential for forming giant T-even phage particles termed lollipops is induced. Whereas echinocandins are alternatives for the treatment of invasive aspergillosis, the efficacy of anidulafungin (AFG) against Aspergillus terreus infection has not yet been explored. Formation of endogenous prostaglandins was prevented with indomethacin.

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The protective factor retained activity after ultracentrifugation, dialysis, freezing and thawing, acid treatment (pH 2), or heating to 56 degrees C but was sensitive to trypsin. We suggest that the geographical barrier of the Isthmus of Kra influences the morphological variation of the skull among the squirrel populations. Gastric atrophy and regional variation in upper gastrointestinal disease. The quinine levels would not normally be considered toxic, however, and it could not be ascertained that the quantity of this drug present contributed to death. In the light of our case and the review of literature we conclude that early recognition of primary endobronchial actinomycosis associated with hemoptysis and proper antibiotic treatment are essential to prevent undesirable complications including unwarranted surgery (Fig.

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Expression analysis of dihydroflavonol 4-reductase genes in Petunia hybrida. Scatter macular photocoagulation for subfoveal neovascular membranes in age-related macular degeneration. Data are presented on the in vitro microbiologic activity of cefprozil against 10,152 bacterial isolates, including most of the clinically important streptococci (e.g., Streptococcus pyogenes, Streptococcus pneumoniae), beta-lactamase-positive and -negative Staphylococcus aureus and Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, Proteus mirabilis, Clostridium difficile, and numerous other gram-negative aerobes and anaerobes.

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Two established and one primary PDA cell line and non-malignant pancreatic ductal cells were used. A new simple and efficient method for isolation of intact WSSV viral particles from infected crayfish tissues with high yield was developed. In all patients with perennial complaints an allergy should be considered. LDMAS is a software suite designed for data retrieval, management and integrated analysis of the clinico-pathological data and molecular results from independent databases. We studied 60 patients with ES (stage: localized in 54, metastatic in six).

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The authors report a real-time medical imager which uses limited diffraction Bessel beams, X-waves, Axicons, or conventional beams. Unfortunately, wide variations in body habitus result in unpredictable variations in tissue attenuation and the specificity of uncorrected SPECT is unacceptably low in many laboratories. The most common and significant cause of disturbances in the normal intestinal microflora is the administration of antimicrobial agents. Macrophages from A/J (A) mice were deficient in IL 1 production, when compared with high IL 1-producing strains, including C57BL/6J (B).

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Transient co-transfections with hypoxia inducible factors showed that HIF-2alpha is a more potent activator of ORF50 expression than HIF-1alpha. Those persons with higher ADP scores had lower diastolic and systolic blood pressure. It lists the various approaches to the modelling of real-world systems and emphasizes the respective constraints on the interpretation of model data. Consequently, radiologists may be required to differentiate PTIs from thyroid lesions, which is most reliably accomplished through the fine needle aspiration-parathyroid hormone analysis.

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Lysates of COS cells transfected with modified hGrzB cDNA were able to hydrolyze tert-butyloxycarbonyl-Ala-Ala-Asp-thiobenzyl ester (Boc-Ala-Ala-Asp-SBzl), whereas lysates transfected with unmodified hGrzB cDNA were inactive. Felbamate: interaction with glycine receptors in human cerebral cortex. The effect of cycloheximide and repeated administration of hydrocortisone on induction of tyrosine aminotransferase gene in the rat liver

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Therefore, it can be concluded that shear stress changes the morphology of laryngeal squamous carcinoma Hep2 cells, and upregulates the tight junction. Activation requires GTP or a GTP analog and is associated with the transfer of cytosolic oxidase polypeptides to the plasma membrane. Diphenylhydantoin (60 mg/kg i.p.) tended to prolong this type of SSAD whereas carbamazepine did not influence it.

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The drug does have a cardiac effect as measured by its action on the human conduction system. We have investigated how the nonclassical receptive field (nCRF) affects dynamic orientation selectivity of cells in the primary visual cortex (V1) in anaesthetized and paralysed cats using the reverse correlation method.

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The intestinal epithelium has a remarkable regenerative capacity, which has made it a prime paradigm for the study of stem cell-driven tissue self-renewal. Due to high levels of viraemia during the initial phase of HIV infection, networks of concurrent regular partnerships in a community could be the determining factor in the development of an AIDS epidemic. Further approaches with phloretin experiments were made in order to characterize the urea transport system.