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Prior to this investigation, no multiplex RT-PCR assay for the detection of dahlia virus and viroid infections existed. Although this therapy resulted in a greater than 4-fold reduction in mean tumor mass of the established tumors, some animals experienced a reinitiation of tumor growth after cessation of conjugate treatment. Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines. The Daphniphyllum alkaloids remain an attractive target in the synthetic community because of their unique framework and promising biological activities.

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Homologs had higher identity and possessed similar orientation and location as roseoloviruses. We also review the major clinical studies about those pharmacological agents and discuss, through the studies about serotonergic agents, lithium salts, disulfiram and related compounds, some peculiar aspects of those trials that we think to be important to develop better strategies for the evaluation of pharmacotherapy of alcoholism.

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Comparison of sequences of the H, F, and N coding genes of measles virus vaccine strains. in addition to metoprolol, there were significant decreases in weekly anginal attacks from 11 to 5 attacks/week, the number of nitroglycerin tablets consumed from 6 to 3 tablets/week, and an increase in the maximum workload from 116 to 126 and 123 W for diltiazem CR and plain diltiazem tablets, respectively, as compared to placebo. The authors sought to determine whether there are differences in language-associated prefrontal activation that discriminate bipolar disorder and schizophrenia.

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Pergolide, a nonspecific dopamine agonist, slightly increased urine output at the highest dose (0.64 mg/kg s.c.). Chronorhythms of the endocrine system and the T-lymphocyte level in the blood in rheumatoid arthritis The goal of this article is to review established and developing clinical therapies directed at slowing progression. Systemic treatment of severe psoriasis--the role of cyclosporine.

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We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases. The association of skin color with blood pressure only in low socioeconomic strata may be due to the lesser ability of such groups to deal with the psychosocial stress associated with darker skin color. The present case implies the significance of the reactivation of tuberculosis in the secondary immunodeficient syndrome (SIDS). Significant sleep fragmentation should be considered when assessing factors leading to respiratory instability during sleep and/or the pathophysiology of sleep apnoea syndromes.

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Because patients could be sent to any of several hospitals, some located far from the catchment area, continuity of care and treatment in the local community were not advanced by diverting admissions from the state hospital. Investigation showed severe villous atrophy without pronounced inflammatory cell infiltrate and with no increase in intraepithelial lymphocytes. Controlling for known pregnancy-related risk factors, logistic regression models were used to determine the risk of the child being small for gestational age, given that the mother, father or both were small for gestational age, and to examine interactions between maternal small for gestational age and pregnancy risk factors. TRH (10 mg/kg) were injected i.v., and the animals were serially decapitated. Electrophysiological investigations of the peripheral nerves demonstrated a generalized character of the disease process, morphological examination of the peripheral nerves demonstrated presence of characteristic although non-specific, limited myelin thickenings, different length of internodal segments, slight evidence of demyelination and remyelination, and presence of axonal component.

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Management of staghorn calculi: percutaneous nephrolithotripsy versus extracorporeal shock-wave lithotripsy. Previously nonphobic anxiety or anxiety crisis occurred in front of the neutral stimulus, without presence of any dangerous stimulus. The response of the adrenergic system of asthmatic subjects to exercise and the role of plasma catecholamines in exercise-induced asthma were investigated.

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This strategy should be further tested in patients at high risk for occult axillary adenopathy and/or distant micrometastases (i.e., tumor size larger than 2 to 3 cm). The higher weight gain of control animals as compared with the zinc-deficient ones in these experiments, even though pair fed, makes it difficult to isolate effects of zinc deficiency per se from those of generalized protein-energy malnutrition. Induction of mouse retinol binding protein gene expression by cyclic AMP in Hepa 1-6 cells.

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Sequence and temperature dependence of the interbase hydrogen-bond breathing modes in B-DNA polymers: comparison with low-frequency Raman peaks and their role in helix melting. Because each patient was tumor-free or had only a small tumor at the onset of this syndrome, the thrombotic microangiopathy may have been induced by chemotherapy. Overall, the results indicated that there were significant differences between the 2 groups in the short-term visual analog scale (VAS) scores, the long-term Oswestry Disability Index (ODI), short- and long-term kyphosis angle, the kyphosis angle improvement, the injected cement, and the cement leakage rates. Our results suggest that a longer duration of CyA therapy may possibly be indicated in these cases.

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Thus, it had a significant protective effect on acinar cells in this model. We tested two hypotheses regarding distributions of mutations among functional domains by using (1) sets of single nucleotide disease mutations for six genes (CFTR, TSC2, G6PD, PAX6, RS1, and PAH) and (2) sets of polymorphic replacement and silent mutations found in two genes (CFTR and TSC2).

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Performance on this test was clearly age-dependent across the time period sampled. Outer membrane modifications of Pseudomonas fluorescens MF37 in response to hyperosmolarity. Viscosity and trypsin activity of pure pancreatic juice in chronic pancreatitis. Ornithine decarboxylase activity was closely correlated with the rate of DNA and RNA synthesis during cell growth, suggesting that the enzyme is as good an indicator of cell proliferation in these cultures as it is in vivo.

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A prospective study was performed over a period of 2 years to identify the cause of peroneal palsy following hip fracture treatment. Complement determinations revealed an intensive activation of the classical pathway before dapsone therapy.

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Chemically synthesized (26)- and (27)-methyl-13C-labeled desmosterol (3, 5) were separately incubated with rat liver homogenate. The constructed recombinant adenovirus contained tetracycline-responsive element which could regulate the expression of inserted genes. The post-stimulation undershoot in BOLD fMRI of human brain is not caused by elevated cerebral blood volume.

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Smoking did not influence the age dependent degenerative changes in the mitochondria of the lymphocytes, but giant mitochondria could be seen more frequently in smokers than in non-smokers. Diagnosis and treatment of mycotic complications in female patient with pulmonary tuberculosis Effect of divergent selection for postweaning average daily gain on front-end soundness of market-weight pigs.

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Cord blood fatty acid composition in infants and in their mothers during the third trimester. The deficiency of dna-2 in combination with RNA interference on mre-11 gene expression synergistically aggravated germ-line development, especially oocyte formation.

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The continued presence of T-DNA sequences in shoots is directly demonstrated by Southern blotting and is also revealed by the presence of the tumor markers octopine and nopaline. Thus, the divalency of the anti-hCG is not the critical factor in the mechanism of antibody action.

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In the past, conserved epitope or algorithmic epitope selections, such as mosaic vaccines, have been designed to diversify immunity and to circumvent potential viral escape. Purification and amino acid sequence of aminopeptidase P from pig kidney. A peripheral fluorescence pattern was observed in the intestinal cells of HIV-infected patients, contrasting with the normal cytoplasmic fluorescence pattern seen in controls. The transverse rearrangement of the monolayer occurring under compression was different in films with the highest and lowest PLP mole fractions tested.

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The findings were the same in the two groups of hyperactive boys: they had more saccades superimposed on ocular pursuit than did normal boys. In this report, 2 pediatric patients are described with severe aspiration pneumonitis and hypoxia for whom conventional therapy with mechanical ventilation and high PEEP was of limited benefit. Elevated ferritin levels and E-rosette inhibitory factor appear to distinguish Stage IV neuroblastoma from Stage IV-S. Suppression of myocardial 18F-FDG uptake by preparing patients with a high-fat, low-carbohydrate diet.

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Endotoxin-induced nitric oxide production in pulmonary artery endothelial cells is regulated by cytokines. In this paper, the mechanism of plasma membrane disruption due to the large transmembrane potentials imposed during electrical trauma is used to explain the particular susceptibility of muscle and nerve cells to damage. The first group consisted of three chemical DDT, aldrin and dieldrin which are generally classified as persistent insecticides while the second group was composed of chlordimeform and parathion, generally considered to be non-persistent insecticides. Forty-one patients underwent surgery before October 1998, and 18 patients underwent surgery after November 1998. Current problems and tasks of medical genetics in clinical practice

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Evaluation of preoperative computed tomography in gastric malignancy. The increase is mostly accounted for by reduction in fabric hole area due to shrinkage.

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To clarify the mechanism of those effects of IL-4, we explored mRNAs whose expression levels were increased or decreased by IL-4 treatment using the method of differential display. Inhibitors of nitric oxide synthase selectively reduce flow in tumor-associated neovasculature. Genotyping of the polymorphic cytochrome P450 (CYP) 2D6 gene is used increasingly in clinical practice. It is recommended that the prenatal version of the PDPI-R be used to predict PDS for pregnant women and the full version of the PDPI-R be used for women during the postpartum period.

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It is concluded that alpha 2-adrenoceptor agonist-induced vasodilation is independent from the existence of the endothelium, and that it is not related to vascular beta- and alpha 2-adrenoceptors and muscarinic receptors, suggesting that the alpha 2-adrenoceptor agonist-induced vasodilation is due to an antagonistic activity towards the vascular alpha 1-adrenoceptors. The occurrence of s-IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM. It has been successfully used for the reconstruction of the defects over the cheek, floor of the mouth, buccal mucosa, tongue, lower lip, mandibular alveolus, hypopharnx and supraglotic larynx. We investigated whether low testosterone levels in older men predict depressive illness over 2 years, while controlling for age and medical morbidity. Therefore, the present study was designed to determine the role of CSPA fibers in the newly developed sciatica model.

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In both direct and delayed pseudopregnancy, twice-daily PRL surges appeared on L-1 and, except for a missing nocturnal surge on L-2 in delayed PSP, continued regularly through L-6. The exercise intolerance associated with laryngeal paralysis may be caused by an increase in the oxygen cost of breathing. The aim of this report is to present the case of a cervical intradural arachnoid cyst surgically removed by an anterior approach with corporectomy.

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However, as cryopreservation of primary human hepatocytes causes a significant loss of metabolic activity, the transport of bioreactors with viable liver cells is required. Seasonal changes in testosterone levels and androgen-dependent organs in male moles (Talpa europaea). Data from 141 full-time employees from 2 universities provided strong support for the proposed mediational model using LISREL VII. Nurses still use reality orientation as a form of therapy, with care plans still discussing orientation in terms of time, place and person.

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The evidence indicates a single evolutionary origin of 4-Cl-IAA synthesis in the Fabaceae, which may provide an ideal model system to further investigate the action and activity of halogenating enzymes in plants. Aspartate aminotransferase (AAT) activity is studied, employing two different procedures, during early development stages of chicken embryo. Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels.

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Biosynthesis in vitro and the pattern of lectin binding receptors in monkey kidney cell surfaces. Atypical Gly-X-Y sequences surround interruptions in the repeating tripeptide pattern of basement membrane collagen.

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The electron-microscopic observations support the lysosomal rupture hypothesis and are compatible with the original proposal of Hers, that the disease results from a deficiency of a single lysosomal enzyme. Analysis of the kinetics of CEA binding to rabbit anti-CEA antibody insolubilized on filter paper discs provided six lines of evidence indicating diffusion control of this reaction: 1) The observed forward rate constant, k1obs, decreased when solvent viscosity was increased with sucrose or Ficoll. The role of pleomorphic adenoma gene-like 2 in gastrointestinal cancer development, progression, and prognosis.

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The seriously burned adult: psychologic reactions, recovery, and management. A comparison was made between the amount of bone that formed in the osseous defects and the amount that formed in the spaces of the porous-surfaced fiber-metal components of the prostheses, directly underlying and adjacent to the defects. These fatty acyl group changes were not accompanied by any alteration in the cholesterol or phospholipid contents of the plasma membranes. Acute renal insufficiency following endourethral surgery with glycine irrigation A scheme is proposed to design a polarization grating that splits an incident linearly polarized beam to an array of linearly polarized beams of identical intensity distribution and various azimuth angles of linear polarization.

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The clinical history, autopsy findings and immunohistochemical results were evaluated, with review of literature. In rats, famotidine also caused a parallel displacement of the acid dose-response curve to histamine to the right with a DR3 value of 24 mumols/kg/hr in stomach-perfused rats anesthetized with pentobarbital, exhibiting a potency 108 times greater than that of cimetidine. Improvement of agricultural life cycle assessment studies through spatial differentiation and new impact categories: case study on greenhouse tomato production. The best candidate is a control protein inhibiting interferon production which is rapidly synthesized following exposure to an inducer. The basis of the technique is the perception that in boys with congenital concealed penis, the penile integuments are normal but they have abnormal attachments, and that incision of the skin and dartos will allow the shaft to extend.

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A methodology is described to utilize dormitory parents in direct care activities for the early intervention of behavioral problems of the school-age child. It was found that according to the main hydrodynamic characteristics including the outlet flow structure, MHV MI-2 was substantially superior to MHV E, BS and SO, and by certain characteristics it approximated to the best foreign MHV SJ. We have isolated the chicken KAL homologue and studied its expression by in situ hybridization during late embryonic development. One operator and two assistants could perform the technique at a rate of 150 to 200 sheep per hour.

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Human cervicovaginal fluid biomarkers to predict term and preterm labor. The observed numbers of various types of convulsions in the offspring are compared to the expected the number based on local age-specific incidence rates. Study of monoprotic acid-base equilibria in aqueous micellar solutions of nonionic surfactants using spectrophotometry and chemometrics. Generation and functional analysis of T cell lines and clones specific for schistosomula released products (SRP-A).

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It is essential in the diagnosis to exclude other diseases of the digestive tract. Recurrent bleeding anomalies under therapy occurred less frequently among the patients treated with MPA than among those treated with NEA. A schistosomiasis transmission model incorporating concomitant immunity.

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Long-term results after cemented total hip arthroplasty in chronic polyarthritis An additional 2-week culture (subculture) was performed for the construct in standard medium with and without the addition of dexamethasone (Dex). In the present work, we evaluate the role of chaperones in a stressed cellular model of hIAPP overexpression. In the absence of acute visual compromise or other signs of disease progression, initial management with intravenous antibiotics for 48 h to cover Staphylococcal aureus and Streptococcal pyogenes with nasal decongestant should be considered before surgical intervention is contemplated.

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Molecular analysis of the nine mutant alleles that accumulated mutated forms of COP1 protein revealed that disruption of the G beta-protein homology domain or removal of the very C-terminal 56 amino acids are both deleterious to COP1 function. The 3,5-diaminoisothiazole derivatives 23-42 were synthesized in excellent yields by oxidative cyclization of 3-amino-3-(dialkylamino)propenethioamide derivatives.

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Multidisciplinary mental health rehabilitation settings often encounter patients with complex comorbid medical and psychiatric issues that require integrative, multifaceted treatment strategies. While extinction is most commonly viewed as an attentional disorder and not as a consequence of a failure to process contralesional sensory information, it has been speculated that early sensory processing of contralesional targets in extinction patients might not be fully normal. S-Ado-Met is formed from methionine and ATP by methionine adenosyltransferase, and is a universal methyl donor, involved in methylation of several macromolecules, e.g.

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Diagnostic evaluations revealed no other cause for the lymphadenitis. Dermoid fistula of the nasal root complicated by frontal lobe abscess

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Spheroplasts of Torulopsis candida yeasts and their oxidizing activity It is suggested that, for all female urethral carcinoma, bilateral ilioinguinal nodes be included in the radiation field.