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Three high MW proteins at 210, 195 and 170 K and a common proteolytic fragment at 95 K were detected in the electrophoretically separated plasma membrane preparations by immunoblotting with polyclonal anti-210 K antiserum. Our study showed that the SmartLipo appeared to be histologically effective for destruction of human fat tissue. Thirty-seven patients were investigated before and after operation for hemorrhoids by uroflowmetry and measurement of residual urine. Application of molecular biology to individualize therapy for patients with liposarcoma. Humans have tripled their brain size since they split from the chimpanzee lineage.

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Although norepinephrine remained unchanged with restlessness but increased with threat, elevation of epinephrine and cortisol levels was common to restlessness and threat. Proliferation and differentiation of retinal progenitor cells (RPCs) are tightly controlled by extrinsic cues and distinct combinations of transcription factors leading to the generation of retinal cell type diversity. The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.

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The results of logistic regression analyses revealed that female infants were more likely to have a BCG scar, and both birth weight and female sex were significantly associated with a reactive PPD induration. When ovulation was induced in immature rats by pregnant mare serum gonadotrophin and human chorionic gonadotrophin, remarkable fibrinolytic activity appeared in the ovaries immediately before ovulation. 1 and .5 mcg EE increased the activities of 3alpha- and 17beta-hydroxysteroid oxidoreductases in both female and male animals. The present results also suggest that these pathological changes in the VPM/VPL are likely a result of lysosomal dysfunction. Unlike rpd3 Delta, in rom2 Delta mutant cells the drug hypersensitivity and the defect in PDR5 expression were suppressed by PDR1 or PDR3 overexpressed from heterologous promoters and by the hyperactive pdr3-9 mutant allele.

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Clinical, electrophysiological, and biochemical effects of des-tyrosine-gamma-endorphin in psychiatric patients. So, allowing a perfusion culture to be created using this system. The evocation of thermotolerance by chemical agents is a largely unexplored area. TM decreased initially, then LM and lastly GM reached the base level around the age of 9 to 13 months.

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One of these proteins appeared to be an integral membrane protein as was deduced from its amphiphilic behaviour. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. The amino-terminal half of Nup145p is similar to two previously identified GLFG nucleoporins, Nup116p and Nup100p (Wente, S. By hemoglobinemia the patients were divided into three groups: hemoglobinemia (group 1), 120-130 g/l (group 2), under 120 g/l (group 3). The results suggest that phagocytosis is accompanied by a microtubule-dependent reorganization of membrane lipids.

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This paper describes the use of a panel of seven monoclonal antibodies (selected so as to include reagents reactive with both epithelial and lymphoid cells) for distinguishing between anaplastic carcinoma and high grade lymphoma. Modulation of high-affinity CNS dopamine D2 receptor by L-pro-L-leu-glycinamide (PLG) analogue 3(R)-(N-L-prolylamino)-2-oxo-1-pyrrolidineacetamide. Mitochondrial toxicity detected in a health product with a boar spermatozoan bioassay.

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Most reports described the retrieval of retained CE via laparotomy. It is important to understand the effect of lowering the forearm/hand skin temperature on grip-strength estimation.

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A clinical cohort of 481 patients was recruited from substance use treatment facilities in Norway, and prospectively interviewed 1, 2, 7 and 10years after the initial data collection at treatment admission. Our goal was to evaluate how the informed consent process was being carried out in Ontario.

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Corticosteroid levels in plasma decreased significantly throughout treatment, declining from 15.2 ug/dL to 9.1 mg/dL (p less than 0.05). Methylprednisolone exhibited a dose-response effect in reducing LDH leakage in cultures, which were subsequently deprived of oxygen and glucose for 4 hr. Relationship between circulating syndecan-1 levels (CD138s) and serum free light chains in monoclonal gammopathies.

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The oestrogenised chick as an experimental model for fatty liver-haemorrhagic syndrome in the fowl. RESULTS: CFS subjects were grouped by several clinical and epidemiological variables thought to be important in defining the illness.

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Peritoneoscopy in medical cases remains largely unpopular in the USA and the UK. Here, we demonstrate that p21WAF1 affects Tax-dependent NF-kappaB signaling by inducing p100/52, an NF-kappaB-related protein.

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Prior to determining the role of VCP on inflammatory responses in vivo, we decided to investigate the role of host complement in the progression of viral infection. The conflicting centromere map positions on chromosomes 1, 3, and 6 could be explained by pericentric inversions or alternative centromere positions on these chromosomes. Ingestive behaviour of the pigeon: stereoselective influence of the opiate agonist levorphanol and its antagonism by naloxone. Chemoprophylaxis with diamfenetide against experimental infections of Fasciola hepatica in ruminants.

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Furthermore, absence of P-gp resulted in significantly increased brain penetration. The coherent state preparation and control of single quantum systems is an important prerequisite for the implementation of functional quantum devices. The effect of thromboresistent surfaces on the development of blood emboli and hemolysis.

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Methods include disproportionately allocated sampling, multiplicity sampling and the use of multiple frames. Spatially resolved microrheology through a liquid/liquid interface. PEDRF is quick and easy to calculate, and showed the strongest and most consistent correlation with O/E LHR.

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Imaging Radiation Doses and Associated Risks and Benefits in Subjects Participating in Breast Cancer Clinical Trials. Precision of CAS was determined by comparison of planned and actual screw position. These studies suggest that there are advantages in studying the enzyme in its native particle-bound state. Delayed-onset enzootic bovine leukosis possibly caused by superinfection with bovine leukemia virus mutated in the pol gene.

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Serum of 100 postmenopausal women was analyzed using multiplex technology for the mentioned analytes. For all 8 specimens, the contact pressure between the subscapularis and the anterior labrum was negligible with the humerus externally rotated up to 90 degrees at all abduction angles in intact, surgically created Bankart, and dislocated specimens. Four manuals were developed to guide the women in the experimental group containing practical ways to treat menopausal symptoms.

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Ten randomized controlled trials were identified and included in the meta-analysis. All patients had routine ophthalmological assessments on admission to the study, including examination of the fundi, visual fields and macular thresholds. Recognition of this fact, when coupled with the observation that leukocyte adhesion to post-capillary venules is a critical first step in the inflammatory process, has led to the development of the concept that inhibition of neutrophil-endothelial cell adhesion (NECA) may represent a novel therapeutic strategy for the prevention of leukocyte-dependent injury in inflammatory conditions.

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In practice, AS was determined using the aorta-brachial pulse transit time and fractional pulsatility indices. A 4-month-old infant underwent surgery for total anomalous pulmonary venous connection to the coronary sinus with obstructions both at the entry of the common chamber into the coronary sinus and at the patent foramen ovale.

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However, the circumferential white matter enclosing the dentate nucleus was less involved. Ninety-three women with BD-I or -II diagnosis (51 with and 42 without suicide attempt history) underwent structural MRI and filled out questionnaires. Moreover, a better understanding of the fundamental mechanism of the photoluminescence of defect centres in SiO2 structure is paramount for their application as white-light sources, non-toxic labels for bio-imaging, or for combining them with metallic and semiconductor nanostructures. Television viewing is hypothesized as a contributing factor because of its documented role in encouraging consumption of highly advertised foods that may lead to the replacement of fruits and vegetables. A complement-resistant HeLa cell line (T638) is blocked at the step of C3 deposition.

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Involvement of T-lymphocytes in the stimulatory effects of EMT6 tumors on medullary pluripotent stem cells of BALB/c mice. Measurement of sublethal metabolic stress in rainbow trout (Salmo gairdneri) using automated respirometry. Macrophage-colony stimulating factor (M-CSF) stimulated microglial cell growth in the serum-free medium.

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Clinical characteristics and course in patients with high titer anti-RNP antibodies. Sequence analysis of the CAEV genome and cDNAs generated from mRNA in infected cells has suggested that one of these ORFs encodes a protein (Rev-C) that is analogous to Rev of visna virus and HIV. These side effects probably result from antagonism of the neurotransmitter gamma-aminobutyric acid (GABA) at the brain GABA(A) receptor complex (GRC). A simple analytic model describing the evolution of the thermal injury during and after exposure of biological tissue to pulses of intense laser radiation is presented. Results of examination and treatment in the three cases described point out the necessary differential diagnosis to effectively screen these groups of patients from among those with more complex diseases.

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Low-quality evidence from two small trials showed that when compared to placebo, LAC may not improve intellectual functioning or hyperactive behaviour in children with FXS. Participation of the ascending serotonergic system in the stimulation of atrial natriuretic peptide release. Although a number of etiologic factors are involved in the pathogenesis of dyshidrotic eczema, hyperhidrosis is assumed to play a significant role.

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Revision of the shunt to ventricular drainage followed by ventriculo-atrial shunting was required for resolution of ascites. The middle ears of all experimental animals remained free of pathologic changes except for the three ears with otorrhea. Here we use that enzyme (tAtf) and the cognate acyltransferase from the related A-40,926 biosynthetic cluster (aAtf) to evaluate specificity for glycopeptide scaffolds and for the acyl-CoA donor.

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The ergonomic evaluation of work stress in the furniture industry. Mobility shift assays using the EA site identified four binding activities (C1 to C4). Tissue plasminogen activator antigen is strongly associated with myocardial infarction in young women.

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Volume rendering of 3D medical ultrasound data using direct feature mapping. Band-target entropy minimization (BTEM) applied to hyperspectral Raman image data. In total, 26 compounds were isolated and identified, of which four are new, namely, two ent-kaurenes (1 and 2), a diterpene lactone (3), and a lindenanolide (4).

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For the derivative of benzylamine, deuterium isotope effects on (13)C chemical shifts are determined. Action of 13-cis-retinoic acid and aromatic retinoid on several cutaneous parameters in hyperseborrheic rats Alcoholism studies should benefit by improvement of research methodologies as already applied to other chronic diseases. The drug could successfully be used in anesthesiological practice.

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This initial matrix-membrane interaction culminated in differentiation of fibroblasts to chondroblasts and osteoblasts. Best practice hospital: a model for cooperative exchange of information in the field of nephrology and transplantation. When de-repressed, this second stem cell pathway leads to an accumulation of stem cells and an enlargement of the stem cell niche. Recent work has provided immunohistochemical evidence for an intracellular localization of some plasma proteins in the central nervous system of chick embryos and of rat, mouse, sheep, monkey and human fetuses.

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miRNAs (microRNAs) were first discovered as critical regulators of developmental timing events in Caenorhabditis elegans. The first, psychophysics, dates back to the nineteenth century and measures the effect of analgesia by quantifying the noxious stimulation required to elicit pain, as well as the maximum stimulation tolerated.

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Structure and function of the cytoplasmic domain of band 3: center of erythrocyte membrane-peripheral protein interactions. These probabilities were defined by the pretreatment clinical stage, serum prostate specific antigen and biopsy Gleason grade of 2,139 patients treated with radical prostatectomy for clinically localized prostate cancer.

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A modification of the standard format of multiple choice question (MCQ) examinations, recently introduced in certain medical schools in this country, is decribed. Group C comprised nine patients who had a second rise of serum CK.

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The underlying mechanism for the thermodynamic helical propensity is not well understood. Using gravimetrical and numerical doses in cultures, good indications of the toxicity of single fibres were found. Glycated hemoglobin can be assayed by methods using different principles, whose performances vary and are difficult to control. Since the IL-2-sensitive and IL-2-resistant sarcomas were induced with MC in mice of identical genotype and share most of their characteristics, they represent a useful model for investigation of structural target cell determinants and functional target cell properties responsible for the sensitivity of tumours to the immunotherapeutic effects of IL-2. The lymphocyte response to purified protein derivative was decreased in the patients as a group when compared to the controls (P less than 0 .

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An intensely stained thick glycocalyx was associated with prominent surface microvilli seen in the following conditions in humans: some control urothelium, inverted papilloma, well and moderately differentiated transitional cell carcinomas and mucin producing adenocarcinomas. To evaluate two of the units (hip and knee), we compared the self-instructional method with a traditional method using assigned textbook readings. A method for the rapid quantitative analysis of eggs in the feces of rats infested with Hymenolepis diminuta is described.

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Medical Benefit/Risk Foundation--a new charitable foundation for the safer use of medicines. Complications of local anesthesia from the standpoint of the practicing surgeon One of these lines was used as a feeder for the isolation of feeder-dependent (A8 cells) and feeder-independent (H9 cells) pre-B-cell subclones present in a spontaneously immortalized line of pre-B cells that originally arose in a long-term lymphoid marrow culture.

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The diagnoses of sinus venosus atrial septal defect and combined partial anomalous pulmonary venous return were confirmed by surgery in both cases. However, despite considerable differences in performance characteristics, all dialyzers were judged to be clinically acceptable in terms of both solute clearance and ultrafiltration characteristics. Previous studies, based on fewer subjects and including mainly subfertile men, have shown conflicting results regarding the influence of overweight and obesity on sperm DNA integrity. Our results indicate that perinuclear localization helps to establish transcriptionally silent chromatin. All amyloid-laden porcine valves had been implanted for at least 33 months before removal, and all except two showed dysfunction and/or severe degeneration of cuspal tissue.

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Incidental learning of probability information is differentially affected by the type of visual working memory representation. Quantitative data representing this loss in projection may enhance patient education and improve our management of patient expectations. When these changes are abrupt and dramatic, the process is referred to as phase change. Intracerebroventricular administration of the alkylating benzodiazepines irazepine or kenazepine (20 nmol) resulted in a complete protection against convulsant doses of pentylenetetrazole (PTZ) for at least one hour, and a statistically significant protection for at least two and four hours, respectively.

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Morphology of experimental lung tumors in albino rats and Syrian golden hamsters This spontaneous AhR translocation into the nucleus was reduced by pretreatment of the recipient cells with the p38 mitogen-activated protein (MAP) kinase inhibitor SB203580. Three underwent PCL reconstruction because of a reparable meniscal tear or instability.

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Psychopathology and shamanism in rural Mexico: a case study of spirit possession. In studies with purified mammalian cell enzymes, adriamycin produced a greater inhibition of DNA-dependent DNA polymerase than of RNA polymerase. Possible inadequacies of energy and protein balance appeared to be associated with an acute inflammatory response, which was characterized by elevated C-reactive protein levels.