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Dietary sugar promotes gene activation in intestinal cell chromatin of adult rats. Yet, so far there is no definitive cellular and biochemical understanding for the differences seen in the spectra from different tissue categories and disease states.

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We attempted to determine whether the coronary vasomotor response to exercise improves after cholesterol-lowering drug therapy with bezafibrate. Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin). Subxiphoid pericardial window in 19 patients showed malignant involvement in six but documented a nonmalignant effusion in 13. Prolonged storage of purified hepatitis B core antigen particles or incubation with human immunoglobulin G preparations containing antibody to the hepatitis B core antigen with or without antibody to the hepatitis B e antigen resulted in the conversion of the polypeptide with an apparent size of 20,600 daltons to ones with apparent sizes of 14,700 and approximately 6,000 daltons, suggesting proteolytic cleavage of the 20,600-dalton polypeptide under these conditions. A 1,064 bp fragment from the promoter region of the Col11a2 gene drives lacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos.

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Nuclear imaging is a more sensitive indicator than plain radiography, but the two studies supplement each other. A two-phase study was conducted to determine if sodium is absorbed in significant amounts by the oral mucosa during use of saline solutions. Since the antiproton beam provided by CERN has a pulsed structure and possibly carries a high-LET component from the antiproton annihilation, it is necessary to correct the acquired charge for ion recombination effects. Spruce beetle fungal symbiont growth varied among species and compounds. We present four applications of fuzzy logic theory in epidemic problems, using linguistic fuzzy models, possibility measure, probability of fuzzy events and fuzzy decision making techniques.

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The median level of multiply spliced HIV-1 RNA was dramatically higher than the median level of unspliced viral RNA in asymptomatic individuals. The varying elastance model shows the dependence of the extent of the reduction of the flow in systole on myocardial contractile force rather than on the pressure developed in the ventricle by the contraction. upQMPSF was used to screen germline mutations in 88 familial ovarian cancer patients negative for point mutations. The fragmentation of healthcare provision has given rise to a wide range of interventions within organizations to improve coordination across levels of care, primarily in high income countries but also in some middle and low-income countries. Concanavalin A-induced activation of thymus cells compared to spleen or lymph node activation is extremely sensitive to the inhibitory effect of hydrocortisone (HC).

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The most common etiological factors of portal vein thrombosis are liver cirrhosis and malignancy. The results show that various neck muscles were innervated by motoneurons in medial motor column of the ventral horn extending from the second to third spinal nerves, and positioned medially to the lateral motor column (LMC).

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Bioluminescence, the biochemical generation of light by a living organism, is a naturally occurring phenomenon. Biochemical and morphological techniques have shown that African swine fever virus (ASFV) enters susceptible cells by a mechanism of receptor-mediated endocytosis. Postpartum women in the Honduran health system: folic acid knowledge, attitudes, and practices. The aim of this study is to elucidate whether interferon regulatory factor-1 (IRF-1), a transcriptional factor with anti-proliferative and pro-apoptotic properties, mediates PPARgamma-induced apoptosis in vascular smooth muscle cells (VSMCs).

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HDM has become an established and effective salvage regimen for children with relapsed neuroblastoma, as well as an effective consolidative treatment for children with high-risk disease (stage IV). Monofilament materials are unreactive and appear least likely to delay healing. Cu(OAc)2 was found to be an efficient catalyst for dehydrogenative synthesis of 1,3,5-triazine derivatives via oxidative coupling reaction of amidine hydrochlorides and alcohols in air.

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Although the concept of in utero treatment of neurological anomalies remains more theoretical and experimental than clinically practical, preliminary evidence from both the laboratory and the clinic has begun to emerge to support continued efforts in this field. How to decode this information into clinical practice remains however, a challenging issue in medical mycology. Identification of B-L antigens on reticular epithelial cells of the bursa of Fabricius.

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Intra-articular hylan G-F 20 (Synvisc) in the management of patellofemoral osteoarthritis of the knee (POAK). Variability of haematoxylin - basic fuchsin - picric acid (HBFP) staining of infarcted myocardium due to tissue storage. It has been reported that human DC subsets express distinct toll-like receptor (TLR), which influences their function.

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The obtained data could provide a useful tool for predicting bull puberty and fertility. With a second heat shock it is rapidly transported back into the nucleus.

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Sequential chemotherapy and late intensification for malignant lymphomas of aggressive histologic type. Successful application of this assay to colonic solid tumors will require improvement in techniques for disaggregation of viable clonogenic cells. Simultaneously, mean arterial blood pressure (MABP), PaCO2, PaO2, and hematocrit were recorded. Some members of this superfamily of enzymes detoxify drugs, whilst others activate carcinogens, or interconvert steroid hormones.

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Mutations and amplification of EPSPS gene confer resistance to glyphosate in goosegrass (Eleusine indica). The effects of serial intravascular transfusions in ascitic/hydropic RhD-alloimmunized fetuses.

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To evaluate the effect of central venous pressure (CVP) on visual outcomes and retinal ischemic consequences in patients with central retinal vein occlusion (CRVO). The neuroradiologic findings in two patients are reported, and include abnormalities within the globus pallidus (both patients) and periventricular white matter (one patient). The carbon dioxide laser is most commonly used, offering precision, minimal blood loss, and prevention of strictures. Arrhythmia vulnerability was assessed with low-amplitude programmed stimulation.

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However, under normal conditions, GSH2-expressing cells in the adult SVZ and in the in vitro expanded neurospheres appear to specify only olfactory bulb progenitors and not striatal progenitors. De- and rehydration behavior of alpha,alpha-trehalose dihydrate under humidity-controlled atmospheres. However, evidence of efficacy is sparse, pointing to the need for a more systematic review for assessing scientific evidence to support therapeutic claims made for ZER and to identify future research needs. Synthesis and in vitro biological properties of novel cationic derivatives of amphotericin B. In contrast, none of the three amounts of alcohol caused a significant impairment in the ability of subjects to voluntarily inhibit their sexual arousal, even though most subjects experienced some deterioration in that ability after ingesting a moderate amount of alcohol.

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Retraction: Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first degree relatives. HWA 486 differs, though, from CsA in that the T-cell mitogens (Con A and PHA) were able to induce proliferation in lymphocytes obtained from animals treated with this compound.

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Neurophysiological evidence for motor planning limitations in children with cerebral palsy. Two methods of mutations for strain improvement were employed to these strains. Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem.

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Hemodynamics, hepatic and systemic NO concentrations, and iNOS expression in harvested liver tissues were assayed. Abnormally low narcissism and rejectionality in val homozygote relatives of schizophrenia patients suggests that the val allele of the COMT polymorphism may be associated with an underdeveloped self-concept phenomenologically similar to made volition and passivity experiences comprising first-rank symptoms of schizophrenia. To understand the progression mechanism of EGC to AGC, it is required to disclose EGC and AGC genomes in mutational and evolutionary perspectives. DNA probes from single microdissected chromosome segments can be prepared using Alu or Adaptor PCR.

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To reduce the incidence of infectious complications it is important to limit sampling from CVC to a minimum. Practical tips for macroscopic examination of formalin-fixed material are listed and several cases are presented for illustration of the theoretical text. Noncovalently and covalently bound lipid on the receptor for immunoglobulin E. The patch was then removed and the subjects were rescanned 2 h later.

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Effect of monotherapy and combination therapy with richlocaine on tissue hypoxia and activity of keratinocyte detoxifying systems in ischemic skin flap. Emergence of a molecular Bose-Einstein condensate from a Fermi gas. Experimental mechanical vascular injury produces a predictable, although rather variable, amount of vascular narrowing due to transient smooth muscle cell proliferative intimal lesion formation. Structural genomics of Caenorhabditis elegans: structure of dihydropteridine reductase. Comparison with the ICRU reference in gynaecological brachytherapy.

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The protein degradation systems are the principle mechanisms for maintaining cellular homeostasis via protein quality control. Problems arise from our dependence on combustible fuels, the environmental risks associated with their extraction, and the environmental damage caused by their emissions. On colposcopy, an atypical transformation zone is frequently observed.

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Combination chemotherapy has been associated with a higher response rate but not improved survival when compared with methotrexate alone. In each animal, heating of the PO/AH area caused panting, defined as an increase of respiratory rate over 100 breaths per minute. Therapy of prostate carcinoma with polyamine synthesis inhibitors. Many jurisdictions have imposed special restrictive bail conditions upon the bail agreements of addict defendants on the heretofore unproven assumption that appropriate remedial conditions of release (for example, supervised drug abuse treatment) will improve the pretrial release performance of addict defendants. Measurements of biomarkers of exposure, of effect and of susceptibility provide information of potential benefit for epidemiological and cancer risk assessment.

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One of the pivotal manifestations of immediate type hypersensitivity is mediator release from a variety of mediator cells, e.g., mast cells and basophils. With recent advances in digital pathology and image analysis, other characteristics of tumor vasculature can also be evaluated. The goal of this study was to design a prolonged release system of the hypnotic agent zolpidem (ZP) useful for the treatment of insomnia.

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Furthermore, among the surviving patients in the surgical group, current ejection fraction in the radionuclide ventriculogram was significantly greater in patients who demonstrated inotropic contractile reserve in their 1971 to 1974 contrast left ventriculogram. The present study has shown that sodium ascorbate decreases cellular iron uptake by melanoma cells in a dose- and time-dependent fashion, indicating that intracellular iron levels may be a critical factor in sodium ascorbate-induced apoptosis. Glycosylation of the mutant lysozymes was confirmed by SDS-PAGE patterns, Endo-H treatment, TOF-MS analysis and chemical analysis. Steric structure of Caf1M, a periplasmic molecular chaperone of Yersinia pestis, was reconstructed by computer modelling based on a statistically significant primary structure homology between Caf1M and PapD protein from Escherichia coli, and using the known atomic coordinates obtained by the X-ray crystallography for PapD. Our data also suggest that the reduction in glucagon secretion may be secondary to the increase in circulating SLI.

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Comparison of the amino acid sequences of the four subunits reveals marked homology among them. The alterations in the external auditory canal ceased almost immediately when treatment of dogs with the aromatic retinoid was stopped but recommenced when it was restarted. Consequently, the standardization of such a culture system is dependent on variations from serum batch to serum batch.

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Using MicroChIP, we characterize transcriptionally permissive and repressive histone H3 modifications on developmentally regulated promoters in human embryonal carcinoma cells and in osteosarcoma biopsies. Monozygotic, monoamniotic monochorionic twins with multiple similar abnormalities

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This suggests that the non-immunoreactive protein may be the precursor to the immunoreactive protein. Disease progression, which includes recurrence at the primary tumor site, is a major cause of treatment failure in patients with mediastinal presentations. Not necessarily in the first specimen, but in the course of the illness. Cognitive factors included perceived job competence and TC attitudes. Porphyrin production by Propionibacterium acnes and that by Propionibacterium granulosum were compared.

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A systematic literature search produced individual data for 29 treated patients with vascular extension of pheochromocytoma mainly to the inferior vena cava. Micellar, discoidal complexes were prepared from L-alpha-dipalmitoylphosphatidylcholine (DPPC) or egg phosphatidylcholine (egg-PC), cholesterol, and human apolipoprotein A-I by the cholate dialysis method. Metaanalysis of data from 20 years of randomized trials of lidocaine prophylaxis in preventing primary ventricular fibrillation (VF) in myocardial infarction used separate data for control and active-treatment groups to model the risk of VF as a function of year of publication and other study characteristics. No quantitative or qualitative differences could be detected in the phosphorylation of glycoprotein Ib beta from resting or activated platelets. The remaining patient suffered from hyperglycemic hyperosmolar non-ketotic coma and Group A streptococcal bacteremia, without an obvious focus of infection.

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A 3-hour glucose tolerance test was done to determine fasting plasma triglyceride and cholesterol levels. Studies have suggested that the spontaneous elimination rate is higher in developing countries, possibly owing to higher incidence rate. Ironically, the lack of machinery to integrate special services into a broad national program has mobilized more creative energy in the United States than has been the case in Britain. HLA-DRB3 genotyping was performed using the PCR-RFLP method and the clinical features of the patients with and without the DR3, 5, 6, 8 group antigens were compared.

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A prospective study was conducted using 50 randomly selected patients diagnosed with both T2DM and hypertension. Physiopathological characteristics of this uncommon fracture are mentioned. Radiosensitivity of the B16 melanoma is not significantly influenced by melanin content.

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The low-affinity transport of DA by the human platelets does not share any of the dopamine uptake characteristics found in neuronal tissue. Results of soil column and batch experiments are presented that highlight research findings over the past several years. Peptides showed synergistic effects when used in combination with conventional antifungals. Therapeutic drug monitoring of vancomycin needs re-evaluation in the hospital to explain why existing methods are ineffective. The generally low performance of national TB and HIV programmes in the top 25 HIV prevalence countries is unlikely to make a significant impact on control of HIV-related TB.

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Boiling water extracts of 132 samples from 54 plant families, commonly used in Argentine folk medicine, were screened for antibacterial activity against Salmonella typhi. Observers reported the horizontal or vertical organization of stimuli with proximity and similarity providing conflicting grouping cues. Comparison of the efficacy of nilvadipine and nitrendipine on circadian blood pressure. PMA induced lamellipodia formation and subsequent migration of the subconjunctival fibroblasts.

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The personality dynamics of homosexuality, psychiatric patient status, and psychological masculinity and femininity were assessed for four groups of 45 male subjects in a full factorial comparison. A decrease in perforin expression by cytotoxic cells could be a major factor in explaining the physiopathologic mechanisms of several alcohol-associated diseases. Transfection of NIH 3T3 resulted in no significant alterations in growth properties.

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Idiotype mapping suggested that MoAb 5B3 had at least three distinct idiotopes at its antigen combining site. This paper describes a number of epidemiological findings relating to the size of the back pain problem within nursing, its distribution across nursing specialties and the comparison of these data with other occupational groups. In DSM-IV, impulsivity and hyperactivity remain combined, but inattention is considered a separate construct. An 18-residue synthetic peptide corresponding to residues 4-21 of cystatin C did not inhibit papain but was cleaved at the same Gly-Gly bond as cystatin C. Intravitreal injection of Rev-2-T-6 cells is a novel model of PIOL in immune-competent hosts that will aid in understanding the molecular mechanisms of the disease.

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The effects of prefabricated bar design on the success of overdentures stabilized by implants. Mice subsequently inoculated with these cells had longer survival times than control animals that received cells exposed to the drug but not ultrasound. The vfr gene product, required for Pseudomonas aeruginosa exotoxin A and protease production, belongs to the cyclic AMP receptor protein family.

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The adjusted survival of patients with IPF in the general population is different from that of hospital referrals which suggests that selection biases affect the survival experience of referral hospitals. Preparation, antimicrobial and anthelminthic effect of diiosothiocyanates Based on a global T2 estimate, the accuracy of VFA T1 relaxometry in the human brain can substantially be improved compared with conventional approaches which rely on the generally wrong assumption of ideal spoiling. Acne rosacea may be more common in black patients than heretofore believed.

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Evidence to date indicates that this innovative procurement process is going to be an unqualified success for both the buyers and sellers of construction services, says Andrew Percival, Alliance Development Manager, Taylor Woodrow ProCure21 Alliance. This research gives further evidence that design complexity should be considered an influential variable for health communicators to effectively reach their audiences, as it embodies the critical first step for message evaluation via electronic platforms. Towards a revision of the South American genus Praocis Eschscholtz (Coleoptera, Tenebrionidae), with estimation of the diversity of each subgenus. Ultrastructurally, the long chain endings resembled extrafusal end-plates.

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IgG1-kappa biclonal gammopathy associated with multiple myeloma suggests a regulatory mechanism. Thirty independently arisen mutants have been isolated in this way and one of them, P 83, has been investigated in detail.

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Selective carotid arteriography can provide useful information in patients with massive epistaxis. Hyperazotemia in the 1st weeks of life due to excess protein intake Serum-induced inhibition of isotonic fluid absorption by the kidney proximal tubule. A monoclonal antibody which detects a 125 kd glycoprotein on embryonal carcinoma cells and is mitogenic for murine spleen cells.

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Induction of latent immunological memory in genetically nonresponsive mice. Necrosis of arteriolar endothelial cells was evident in virtually every vessel section studied. Bronchiolar emphysema was found in an infant of 1.5 months of age in the course of a morphological investigation of a resected 5th segment.