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Four clones containing cDNA inserts (0.47-1.42 kb) without any significant homologies to the known sequences in the Gene Bank were obtained by means of statistic selection. An elderly man with relapsing myasthenia gravis was found to have hypergammaglobulinaemia, a monoclonal peak of gamma mobility and paraproteinaemia IgG, type K. Re-expression of each form of CD44 in a B cell line allowed cells transfected with the hematopoietic but not the epithelial form to bind to viable rat lymph node HEV cells in primary culture. Temporal trends were analyzed by means of simple linear regression.

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Marked differences in arylhydrocarbon hydroxylase activity were observed between tissues and individuals, with liver being the richest source. It may be possible to improve healing of bone defects in humans using stem cells from bone marrow.

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Antibiotics appear to have no benefit in treating acute laryngitis. Evaluation of dental radiology students in Canadian dental schools.

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Integrating classic work with recent insights, emphasis is placed on efforts to pinpoint the precursor cells for autoantibody-secreting cells and the unique stimuli and pathways by which they are activated. However, we will be able to accurately establish the sensitivity or specificity of the individual tests only when we have results of large prospective studies. Megestrol acetate in the two higher doses retarded growth and gave a low weight for the levator ani muscle at autopsy indicating an anti-anabolic or catabolic action of megestrol acetate in high doses. Under the 1 sec ISI condition the two components of the CNV are confounded.

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In contrast to the classic examples of tissue interactions prevailing in the formation of tetrapod limbs or pectoral fins that can only take place when the interactive tissues are in intimate contacts, the interactions in deer antler formation are novel in that the inducer and the responder are separated by a distance of 1-2 mm. The high degree of heterozygosity for mdg3 which in addition does not deviate from the expected value, suggests that recent high rate of movements has strongly countered the population host effect on this element. The ratio of Ib to Tn was computed to correct for differences in Ib due to differences in transmission of sound.

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Stabilization of human epidermal growth factor (hEGF) in aqueous formulation. Continuous efforts are needed to discover novel CAR inhibitors, with extensive understanding of their inhibitory mechanism, species selectivity, and discriminating power against other xenobiotic sensors. Bone lead concentration in his tibia, calcaneous, and patella were 102, 219, and 182 ppm, respectively.

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However, a single serum sample cannot be sufficient and may sometimes be misleading if not plotted with an adequate temporal reference standard (chronodesm). Studies on the role of sex-hormone-binding globulin (SHBG) in benign prostatic hypertrophy in men. Using Fisher discriminant analysis (FDA) and leave-one-out cross-validation (LOOCV), we discerned an ALS-specific signature.

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These phenotypes were unstable and opaque and translucent colony variants were observed to interconvert at high frequency, suggesting that a phase-variable mechanism was responsible. Sonography has become the most sensitive and accurate method for detection of this abnormality. We describe two situations in which the recognition of hapten can compensate for the lack of recognition of appropriate H-2 gene products in hapten-specific, H-2 restricted, T lymphocyte-mediated cytolysis.

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For correction of hypovolemia, human serum albumin solutions can adequately be replaced by present day colloids such as hydroxyethyl starch solutions. Effects on platelet consumption and monocyte prostaglandin production in patients with advanced cancer. Various pulmonary lesions produced by the different routes used and the multiple obstetric problems during pregnancy, such as abnormal labour with products showing cerebral damage and teratogenic lesions due to the use of cocaine are presented.

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A recent review concludes that the agreement of data across ActiGraph accelerometer models for children and youth still is uncertain. The evidence presented shows that the M2 protein of influenza A viruses exists in infected cells as a homotetramer composed of two disulfide-linked dimers held together by noncovalent interactions. Recent interest and controversy has centered about the efficacy of gram-negative bacillary vaccines, antiserum against endotoxin, and pneumococcal vaccines. The renewal of the epithelium has been studied with light microscopic autoradiography, using tritiated thymidine.

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A 58 year-old man presented with a large mass in the upper eyelid of his only eye. Several lines of evidence suggest the involvement of the epoxides, i.e., chloroethylene oxide or bromoethylene oxide.

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Larger, controlled studies of aripiprazole as monotherapy and as augmentation in partial responders to selective serotonin reuptake inhibitors are needed. For example, in the studies we reviewed, many instances could be found where samples were inadequately described or where response rates and completion rates suggest that the final sample may no longer be representative of the population of interest.

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Risk factors for adverse drug reactions--epidemiological approaches. In cells that expressed both receptor types, heterodimers of mutant PDGF B and wild-type PDGF A gained substantially in their ability to recruit and trigger alpha, but not beta, PDGFRs. Nevertheless, amylin (100 nM) blocked the activation of glycogen synthase by insulin. After controlling for age, height, and smoking in multivariate regression models, decrements in FVC and FEV1 were found to be associated with cumulative exposure to beryllium in the period up until 20 years before the health survey.

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Sequential cytological events in late spermatogenesis of LIza aurata were studied from the stage secondary spermatocytes to that of mature spermatozoa. 10 healthy blood donors persistently seropositive for anti-HBs and without a history of clinically overt viral hepatitis were observed for periods of time ranging from 46 to 57 months.

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The latter exhibit the typical distribution pattern of the respective articular cartilage matrix. Providing the right stuff: feeding children with chronic renal failure.

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However, such assessments may be derived from further analysis and modelling of field data. Transient tachypnoea of the newborn: two distinct clinical entities? In common with immunocytochemistry, immunoreactivity was only detected with the SP antiserum. These effects serve to rapidly decompress blood volumes and thereby reduce cardiac work.

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Future approaches to pharmacologic therapy for congestive heart failure. Application of phytohormones generally led to a reduction in shoot Ni concentration. Strong labeling was observed in breast carcinoma cells and faint labeling in other tissues.

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Coffin-Lowry syndrome is an X-linked mental retardation disorder with dysmorphism caused by mutation of the ribosomal S6 kinase (RSK2) gene. This was true for the majority of gastric cancers, but a small proportion appeared to be proliferating more rapidly. External carotid artery ligature is a useless and even risky procedure, whereas surgery should be preceded by tumoral embolization whenever possible.

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66 spouses participated in a six months intervention with 12 group sessions. The results suggest the occurrence of haplotype and nucleotide diversity. Pharmacogenomics as an aspect of molecular autopsy for forensic pathology/toxicology: does genotyping CYP 2D6 serve as an adjunct for certifying methadone toxicity?

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Unfortunately, many patients requiring these surgeries are already in moderate-to-severe pain, necessitating high doses of oral or transdermal opioids preoperatively. Caregivers can benefit from stress reduction techniques using MBSR. No other components of the brainstem auditory system react to any extent with the antisera.

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With increasing Ptp to 30 cmH2O, values of both the arterial and venous Px relative to Ppl (Px - Ppl) decreased to approximately -5 cmH2O, indicating that the magnitude of the vascular-parenchymal interaction with increasing Ptp is similar for both arteries and veins in the in vivo state. The system covers 80 to 90 percent of all dental radiographs and results in a clear report requiring far less production time than previously. These mutations indicate that this central region of both of the fibrillins plays a critical role in human embryogenesis. Formation of malignant tumors in benign bone neoplasms and osteomyelitis The neuroprotective effects of xenon and helium in an in vitro model of traumatic brain injury.

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Isotherm studies confirmed that Zectran sorption occurs in a direct relation to the amount of chemically oxidizable carbon present in the bottom sediments or peat moss. The concentration of extracellular nucleotides is controlled by various phosphatases, prominent among which are apyrases EC 3.6.1.5 (nucleoside triphosphate diphosphohydrolases, NTPDases).

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The fine structure of Schistosoma mansoni sperm (Trematoda: Digenea). Short-term intravenous administration of M-CSF at a dose of 10(6) units daily had no antitumor effect in vivo. It was noted that the suppression was effective against dengue virus antigen also.

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Integrin alpha 2 beta 1 mediates the binding of several epithelial and mesenchymal cell types to collagen. The current characteristics indicate the possibility that the transmembrane ion transport by this important calcium ionophore is initially by a carrier mechanism but with time is by a channel or pore mechanism due to the aggregation of the molecule in a lipid matrix. At the same time, comparison of the values of volumetric pulmonary rheography and accelerative kinetocardiography, treated by the method of linear discriminant functions, with the findings of pulmonary roentgenography showed only a small percentage (lesser than that in the clinic) of non-coincidence in the diagnosis of congestive left-ventricular failure.

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The disease was characterised by diarrhoea, weight loss or poor weight gain, anaemia, serum protein changes and eosinophilia. Posttranslational uptake and processing of in vitro synthesized ornithine transcarbamoylase precursor by isolated rat liver mitochondria. Among the questions: 1)Do physician factors contribute to child diagnosis, treatment choice, and clinical improvement? Reconstituted antigen-poor collagen preparations as potential pulp-capping agents. It discusses complications, clinical recognition, the polysomnographic report, and treatment of OSAHS, including strategies for troubleshooting problems associated with continuous positive airway pressure therapy.

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The effects of age on felodipine pharmacokinetics and pharmacodynamics lead to a heightened antihypertensive response in the elderly. Survey conducted included noise measurements at aforementioned check posts for one month and Performa based interviews of traffic wardens. This article describes the infant with transient neonatal diabetes and reviews the clinical characteristics of both the transient and permanent forms. It is therefore possible that certain smokers are more susceptible to inhaled cigarette smoke and such individuals may be those who develop chronic airflow obstruction. Plasmin activity and fibrin degradation products (FDP) are found in alpha 2-plasmin inhibitor (alpha 2-PI) deficient plasma only when clotted, but are not found when the plasma is not clotted.

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It refers to a surgical procedure by which utilizing a mechanical barrier to create a secluded space around the defect to permit bone regeneration without the competition of other tissues. Proceedings of the Second Congress of the European Society for Developmental Pharmacology.

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Evoked cortical potentials following stimulation of the urinary bladder could be recorded from all patients except subjects with complete transverse spinal cord lesions. High mobility group box 1 (HMGB1) protein: possible amplification signal in the pathogenesis of falciparum malaria.

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However, few analyses contextualize dual method use within the sexual episode, include reports from men or explore gendered patterns in reporting. Low-voltage and abnormal records were associated usually with larger ulcers of the stomach or duodenum. The work represents an important initial step for understanding the evolutionary history of chromatin and how epigenetic modifications affect gene expression in response to environmental cues in marine environments. These data show that repetitive administrations of hpGRF-44 can induce plasma GH responses in some GH deficient patients who do not respond to a single iv bolus of the peptide. The use of these small molecules to probe biology and treat disease is advancing towards a new generation of anticancer therapies.

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An understanding of the limitations of tests in aiding diagnosis is required. Improved fat suppression in STIR MR imaging: selecting inversion time through spectral display.

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We report 51 cases of PAPVR diagnosed by cardiac catheterization and evaluated from the aspects of age, sex, type and associated anomalies and diseases. High incidence of thrombosis of the portal venous system after laparoscopic splenectomy: a prospective study with contrast-enhanced CT scan. Coronary artery bypass grafting using the right gastroepiploic artery In addition to demyelination, loss of axons, and neuronal cell death, thickening of venular wall and fine capillary neovascularization strongly suggested chronic circulatory insufficiency. Because the selection of a surgical procedure for a woman with genuine stress incontinence depends in part on the presence or absence of urethral hypermobility, this observation has important implications for the evaluation of women with genuine stress incontinence.

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However, few consistent changes in interpeak latencies were shown in all rats. The indication for an operation is the obvious dislocation of the osseous fragments. Drug use patterns and risk factors of adolescents with physical disabilities. This literature review has demonstrated the utility of physical rehabilitation in HCT, its impact on cancer-related fatigue, and to outline the current state of the literature on these topics. The major difference between simple RFs in these areas is the coarser spatial scale seen in area 18.

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We have studied the expression of the c-jun gene during dimethyl-sulfoxide (DMSO) induced differentiation of Friend erythroleukemia (F-MEL) cells. Respiratory failure in acute pancreatitis: the role of free fatty acids. Sarcoidosis--underevaluated cause of malignant ventricular arrhythmias In spite of the hormonal alterations brought about by the gonadectomy and their differing metabolic response, the ovariectomized females did not have a mortality rate significantly different from the intact females.

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The effects of subcutaneous injections of vasopressin on the passive avoidance behavior of rats were investigated in an extensive study. Hemodynamic rounds series II: hemodynamics of dual-chamber pacing and valsalva maneuver in a patient with hypertrophic obstructive cardiomyopathy.

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We report a case of human echovirus 11 infection in a neonate at the time of Bornholm disease in late pregnancy of the mother. Superior acute and 1-year outcome has been demonstrated following PVI, using the second-generation CB in patients with paroxysmal AF. The protective activity of T cells in vivo correlated well with the in vitro T cell cytotoxicity for MC-B6-1 tumor cells, as both were depressed in old mice.

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The RBL-5 lymphoma has previously been shown to be highly sensitive to natural hybrid resistance, under the control of H-2 genes at the host level. The essential cytologic findings included a dual cell population consisting of mononuclear stromal cells and multinucleate giant cells.

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At the time of evaluation, 70 per cent of the patients had excellent or good results. The optimal therapy for all end-stage renal failure complications is definitely renal transplantation. Cecal diverticulitis is a relatively rare problem in the Western world.

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There was more evidence of arthrodesis seen at all time points with intra-articular drilling. Shunt fracture secondary to calcification is extremely rare, and presentation as a breast lump has not been previously described. Isolation and characterization of cDNA clones encoding a 32-kDa dense-granule antigen of Sarcocystis muris (Apicomplexa). These results confirm the hypothesis that mobilization of intracellular calcium is the primary step in the action of carbachol on pancreatin acinar cells and contributes to the submaximal secretory response of acinar cells induced by high concentrations of carbachol.

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Histone modifications and rapid IL-4 transcription were absent in conserved noncoding sequence 1 (CNS-1)(-/-) cells lacking an 8-kb-distant enhancer in the IL-4/IL-13 intergenic region, but also in CD4(-/-) and Itk(-/-) cells, which have similar Th2 deficiencies. Controls were closely related family members of the same sex and similar age without the disease, clinically or biochemically. Experimental methods, such as adenohypophysis grafting, hypophysectomy or use of antithyroid drugs, which stimulate or depress the thyroid function of the embryo, modified accordingly the regressive processes occurring in the mesonephric Malpighian corpuscles, particularly at the level of the glomerular basement laminae. Efficacy and interaction with beta-lactamase-producing organisms in the pharynx. We discuss possible implications of these findings for the induction of peripheral tolerance.

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Particular concern is directed toward adaptation of current therapeutic models to community residential practice (foster homes, halfway houses, group homes). The influence of catecholamines and prostaglandins on calcium efflux and filtrability of thermally damaged erythrocytes: an in vitro study.