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These results suggest that the MAPK cascade consisting of Raf-1, MAPKK, and MAPK and the SAPK cascade consisting of MEKK, XMEK2, and SAPK are both activated in response to osmotic shock. Radiation protection day 1977: what is the truth about radiation? After positive class III-V cytology, the standardized incidence ratio of endometrial carcinoma was 1.6 (CI 1.0, 2.2) and that of vulvar carcinoma was 5.8 (CI 2.3, 12). This study was designed to define the effects of beta-adrenergic blockade on aortic lysyl oxidase (LO), an enzyme responsible for elastin and collagen cross-linking, and aneurysm formation in the blotchy mouse.

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We defined the intensive phone use at the wheel group as drivers who receive or send at least five or more calls per day while driving. The results of this review indicate that although there are several inherent limitations in this type of research, various groups of investigators have demonstrated that eating disorder patients will engage in pathological eating behaviors in structured laboratory settings and that results can be obtained fairly consistently. The level of beta-actin mRNA was elevated in resting cells by epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate and to a lesser extent by fibroblast growth factor, insulin, and dibutyryl cyclic AMP-elevating agents. A role in the absorption of neutral lipids, mainly in pathological situations, is postulated.

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In the general population, the diabetes-associated alleles are discreetly associated with hyperglycemia presumably due to decreased insulin sensitivity. Within this perineal region skin gland volumes were greater dorsally than ventrally (P less than 0.01). Hepatic resection is a well-established therapy for patients with liver metastases from colorectal or neuroendocrine carcinoma. So we conducted this retrospective study in order to compare the efficacy and safety of different second-line treatment regimens.

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Vittatalactone, a beta-lactone from the striped cucumber beetle, Acalymma vittatum. ABC successfully identifies previously characterized functional SNVs, such as the rs4784227 breast cancer risk associated SNP that modulates the affinity of FOXA1 for the chromatin. This observation suggests that CAPL may play an important role in the acquisition of metastatic potential of human mammary epithelial cells. Chronic granulocytic leukemia (CGL) terminates in a disease similar to acute leukemia. Noninvasive transcutaneous cardiac pacing: modern instrumentation and new perspectives.

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Susceptibility of bacterial isolates from AIDS patients to six fluoroquinolones. The S-adenosylmethionine (AdoMet) dependent methylation of a small peptide-N-acetyl-S-geranylgeranyl-L-cysteinyl-L-alanyl-S-geranylgeranyl- L- cysteine (Ac(GG)CysAla(GG)Cys)--was investigated using membranes from a variety of bovine tissues as sources of enzyme.

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In support of the potential role of autoimmunity in ALS, two immune-mediated animal models of motoneuron disease have been developed that resemble ALS with respect to the loss of motoneurons, the presence of IgG within motoneurons and at the neuromuscular junction, and with respect to altered physiology of the motor nerve terminal. The STAT3 staining was strongly positive and TUNEL staining was weakly positive in the eyes of the experiment group. These data suggest that halothane anesthesia per se affects glucose metabolism. Hepatocyte NO production and iNOS mRNA levels were markedly enhanced by the LPS-activated Kupffer cell conditioned medium, but these effects were reduced by heat treatment or anti-TNF antibody.

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Other drugs like Flt3, AS101 or antibodies against IL-10 have been tested only in experimental models. In this context, the use of free light chains (FLCs) has been incorporated into many guidelines. Mutants of either Myc or Max that are deficient for heterodimerization fail to regulate the prothymosin alpha gene, suggesting that a heterodimer between Myc and Max activates the prothymosin alpha gene.

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In contrast, actin mRNA was evident in all the preparations of mammary glands. Functional MRI predicts memory performance after right mesiotemporal epilepsy surgery.

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We report the occurrence of seminoma and dysgerminoma in father and daughter. Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test: comparison to fluoxetine and imipramine.

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A woman with an apparent non-mosaic 45,X delivered a 46,X,der(X) liveborn female. Overall aggregate agreement of men and women is high but lower for subgroups of the population, particularly among various ethnic groups. GHB was administered to 10 schizophrenics concurrently with low-dose fluphenazine in a 6-week double-blind crossover study. The histologic, immunohistochemical, and electron microscopic findings in our case, as well as in others reported, suggest that its histogenesis may be related to Schwann cells.

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Alloxan induced diabetic neuropathy is treatable with gangliosides even 30 days after intoxication. Dissecting aneurysms of the cerebral arteries are uncommon vascular malformations. Inexpensive, readily available, heat-labile tubing was used to adapt the esophageal balloon for use in small children, keeping possible complications at a minimum. However, to date, there have been no reports of progressive neurological deficiencies due to the co-existence of two significant pathologies contributing to intradural and extradural compression. This study examined the risk factors associated with failure of enhanced recovery protocol after major hepatobiliary and pancreatic (HBP) surgery.

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To determine the effects of acute restraint stress on the initiation of allergic rhinitis in a murine model. These findings are consistent with the hypothesis that genetic factors account for much of the variation of serum Lp(a) in both populations. The irradiated breast underwent only minor changes during pregnancy and postpartum but produced small amounts of colostrum and milk for 2 weeks postpartum.

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Histochemical demonstration of free and bound iodine in the thyroid gland This result is in contrast to studies with other Ad5 mutants with lesions in the equivalent protein. Overall club drug prevalence rates were nearly twice those obtained for MDMA alone. With the recent interest on the theranostic approach, there has been a renewed interest for alternative radionuclides in nuclear medicine.

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The human amnion is a site of MHC class Ib expression: evidence for the expression of HLA-E and HLA-G. Inflammatory cytokine removal by an activated carbon device in a flowing system.

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Telomere dynamics were imaged for several hours using digital fluorescence microscopy. Enterotoxigenic capacity and properties related to this characteristic in staphylococci isolated from mastitic milk

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Lansoprazole 30 mg and 60 mg once daily are more effective than ranitidine 150 mg twice daily in the short-term treatment of reflux oesophagitis. It is designed to isolate systematic disturbances and common biological underpinnings from next-generation sequencing (NGS) data. The SIR-FMD project is a partnership between the Department of Genetics and Reference Centre for Rare Vascular Diseases at the Georges Pompidou European Hospital in Paris and the Medical Informatics and Knowledge Engineering Laboratory of Inserm.

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The placenta that shows abnormalities in angiogenesis and maturation may lead to fetal hypoxia and compromise. The protein and glycan homogeneity of SAP and the integrity of AP suggest that the complete glycoprotein structure is important for the normal and the pathophysiological functions of this molecule.

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The subjects were asked to memorize four combinations of paired visual stimuli on an illuminated tableau. In addition, this assay showed a greater induction of enzymatic activity correlating with syncytium formation in comparison to a similar incubation with the HeLa-CD4-LTR-beta-gal indicator cell line. Proceedings of the Fourth Biennial National Conference on Health Issues in the Arab American Community. A procedure is described for the partial purification of pyruvate carboxylase (pyruvate:CO2 ligase (ADP-forming), EC 6.4.1.1) from the flight muscle of the locust (Schistocerca gregaria). These new findings promote our understanding on how smooth muscle contraction is regulated at cellular and molecular levels.

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The electrophysiological effects of verapamil (racemic compounds) and its optical (d- and 1-) isomers on canine ventricular myocardial fibers were investigated in current clamp conditions using single sucrose gap chamber and microelectrodes. Decomposition of molecular types of triglycerides by lipoprotein lipase in man. This study confirms that partial volume averaging is one of the primary limitations in resolution of small structures of the temporal bone.

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SLC27A6, RAB11A, ABCA8, JAM2, HNMT, GSTM1, and CDKN3, which play critical roles in regulating the expression of ESCC, were identified among the key genes involved in the signal transduction networks. Special features of the therapy of hematologic diseases in old age.

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Uptake of carbon monoxide and hydrogen at environmentally relevant concentrations by mycobacteria. Complications associated with general anesthesia and laryngoplasty in draft horses are higher than reported for light breed horses under similar conditions. Group A had povidone iodine ointment, and group B had ointment base applied for 7 days to the healing incision.

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From these results, he was diagnosed as having glycogen storage disease with normal acid maltase. Changes in gene expression, cell physiology and toxicity of the harmful cyanobacterium Microcystis aeruginosa at elevated CO2. Circulating atrial natriuretic polypeptide in essential hypertension. No data are readily available on repeated measurement of glomerular filtration rate during prolonged treatment of mild hypertension in patients with normal or near-normal renal function.

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During pressure support ventilation, P0.1 may be a more sensitive parameter than the assessment of breathing pattern in setting the optimal level of pressure support in individual patients. Other changes influenced the rate of oxidation by all three enzymes similarily.

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Transfected human B lymphoblastoid cells express the mouse Ad beta-chain in association with DR alpha. To determine whether elderly patients documented to have nonprotective titers of anti-tetanus antibodies (ATA) are able to achieve and maintain protective ATA titers for at least 1 year after tetanus immunization. The BA aneurysm was completely occluded, but part of a coil migrated into the BA from the SCA aneurysm during the procedure. In the majority of patients with soft tissue sarcomas of the anterior compartment of the thigh, it is possible to preserve a small portion of the quadriceps with intact nerve supply without compromising on the radicality of the procedure or the local control rate. We conducted a retrospective study at a tertiary referral hospital in South Korea from November 2010 to March 2011.

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Detection of antibodies specific for HLA-A,B,C,DR,DQ and DP by the erythrocyte antibody rosette inhibition (EAI) and immune phagocytosis inhibition (IPI) tests. Relative to a planar supported lipid bilayer, lipid loading in a 6.6 microm thick crystal was 15-73 times greater, as observed by fluorescence microscopy. Contribution of menthofuran to the hepatotoxicity of pulegone: assessment based on matched area under the curve and on matched time course. Monoclonal antibodies identify the protective antigens of sporozoites of Plasmodium knowlesi. Subcortical Region Segmentation using Fuzzy Based Augmented Lagrangian Multiphase Level Sets Method in Autistic MR Brain Images.

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Bacteriological examination of ulcer secretion identified Pseudomonas aeruginosa. At low ionic strength the fibers unfold and appear as the familiar chains of nucleosomes (80 A in diameter). The entropy is used to measure the randomness of the received signals and the FP can be determined by the decision of the sample which is followed by a great entropy decrease.

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Replacement therapy with GH in hypopituitary adults for 6-18 months produced a sustained increase in bone turnover (both formation and resorption). The thioredoxin (TRX) system (TRX, TRX reductase, and NADPH) is a ubiquitous thiol oxidoreductase system that regulates cellular reduction/oxidation (redox) status. A total of 120 hospitalized cases of three- to seven-year-old preschool children with cleft lip and palate were selected from May to October 2011.

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As their latencies (measured extracellularly) were similar to that of e.p.s.p.s in motoneurones, they were assumed to receive a monosynaptic muscle spindle input. Moreover, there was a suggestive localization of verbal praxis to Brodmann areas 44/45. Prediction and classification of protein subcellular location-sequence-order effect and pseudo amino acid composition. Protective eye shields are recommended for use during dental procedures. Each made serious suicide attempts which resulted in their hospitalization.

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Reactivity of T-lymphotyes of normal subjects in relation to age and sex Tensor-based PCA is used to obtain transformation matrices, and coefficients are sequentially shrunk by the linear minimum mean square error. To unveil the participation of the different Sindbis virus structural proteins in late permeabilization, transfection experiments with each late gene by separate have been carried out. This finding suggests that the OFC function, as measured by decision-making tasks, is preserved in the early phases of schizophrenia.

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Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using specific stimuli - a temperature gradient, fluid flow, and a chemoattractant gradient, respectively. Cotransporter activity was enhanced by forskolin in both lines but to a considerably greater extent in subclone Cl.19A, in which the number of bumetanide binding sites was also observed to increase.

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This paper considers the pulmonary side-effects on the basis of a case observed by the author. Surgery, radiotherapy and chemotherapy, alone or in combination, are currently the prevalent treatment modalities. The Forssman pentaglycosylceramide was an abundant glycolipid in the MDCK II subline, but was absent in the MDCK I subline. Glu-plasminogen was eluted by changing the pH of the eluent and Lys-plasminogen by using an eluent containing 6-amino-hexanoic acid.

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The portogram showed complete occlusion of the shunting vessel 4 months after the PTCE. The accuracy of these investigations, however, has not approached that of an experienced parathyroid surgeon. The virus variant isolated with mAb 49.8.9 (H3-49) was strikingly different and caused disease in CBA and A/J mice but not in DBA/2 animals, suggesting that the major histocompatibility complex association of the disease had been altered. In many cases, the basis of the species differences is differences in metabolism and pharmacokinetics.

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Latencies in the vergence open loop and accommodation open loop conditions tended to be shorter for the stimulated system than the open loop system in both cases, and all latencies were typically less than 2 s across the infant age range. Low-temperature adsorption spectroscopy reveals marked shifts in the Qx absorption band of BPheM. Locomotor effects of amantadine in the mouse are not those of a typical glutamate antagonist. Advantages of the scanning ion microscopy for mapping halogen corticoids in normal and transformed cells in culture. Vitamin B12 deficiency induced in the fruit bat by a combination of dietary deprivation and exposure to nitrous oxide (N2O) is accompanied by profound neurological impairment, thus providing an experimental model for the study of vitamin B12 neuropathy.

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A G114D mutation was located in the third transmembrane helix, which had not previously been directly implicated in transport. We identified tup1 and cyc8 mutant alleles as the suppressor of osmo-sensitivity of the hog1Delta strain. A 20 kDa protein that cross-reacted with a polyclonal HSV-1 UL45 antiserum was also detected in cells infected with HSV-2 strain 333. Bacteroides thetaiotaomicron can utilize a variety of polysaccharides, including charged mucopolysaccharides such as chondroitin sulfate (CS) and hyaluronic acid (HA). Plasticity of GABA- and glutamate-containing terminals in the mouse thalamic ventrobasal complex deprived of vibrissal afferents: an immunogold-electron microscopic study.

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The use of systemic corticosteroids is a known risk factor for the development of cataracts. Prevalence of depression and its correlates among undergraduates in Sri Lanka.

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Sinus Width Analysis and New Classification with Clinical Implications for Augmentation. We present a framework for comparative evaluation of classifiers using only limited amounts of training data by using random repeated sampling (RRS) in conjunction with a cross-validation sampling strategy. Information on the patients from their doctors concerning noticeable side effects of psychopharmaca proved insufficient. Diabetic cardiomyopathy: microangiopathy and myocardiac cellular damage

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Future studies should assess whether benefits at earlier stages of the life-course influence long-term risk of CVD. Genomic DNA analysis identified a 1.5 kilobase deletion, spanning exon 3 and including extended flanking intronic sequence. Microsomal oxidation is also sensitive to trypsin digestion, and reactivation is dependent upon the addition of purified, detergent-solubilized cytochrome P-450 reductase.

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Subchronic inhalation neurotoxicity studies of ethyl acetate in rats. Male-specific transplantation antigen (H-Y)-immune cytotoxic T cells of some individual CBA/H mice exhibit lytic activity on male and female allogeneic targets (e.g., H-2b).

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