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Studies with Jak1 kinase inactive 293 cells that were stably transfected with a Jak1 kinase dead dominant negative construct, and the mutant cell lines SAN (IFNalpha-/beta-), U2A (IRF9-), U4A (Jak1-), and DKO (IRF1-/IRF2-) show that the IRF7 transcription activated directly by VAF is distinct from and independent of the IFN signaling pathway. The major individual molecular species of glycerolipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylglycerol, phosphatidylinositol and diacylglycerol of rat lung were determined quantitatively as diacylglycerol acetates. Lod scores of less than -2 were obtained over the whole region from D4S192 to D4S413 encompassing MLR. We also attempted to correlate this with the histological pattern of these tissues. That is, a high level of ether-linked lipids and low percentages of long chain polyunsaturated fatty acids along with an accumulation of monoenoic fatty acids in phospholipids.

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A comparison of two Nicotiana attenuata accessions reveals large differences in signaling induced by oral secretions of the specialist herbivore Manduca sexta. Such changes are likely to involve myotoxin acceptor site(s), which remain(s) to be identified. A previous finding - that intraoral exposure produced substantial mineralization of abraded enamel after one h, and a slower rate of mineralization during the next two h - was confirmed, and it was shown that the rate of mineralization decreased with a decrease in the pore volume of the enamel.

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Insertion/deletion polymorphism in the angiotensin-converting enzyme gene is associated with atrial natriuretic peptide activity after exercise. A new approach to the classification of protein-energy malnutrition (PEM) in adults is proposed. In many tubules, a bundle of naked nerve fibres accompanied the odontoblast process for up to 50 microns located in concavities of the surface of the process (type I relationship). Transverse vaginal septum in the specific-pathogen-free Wistar rat. Changes in prostaglandin levels and reversal of endotoxin effect.

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Expression of scavenger receptors on renal cell carcinoma cells in vitro. Methods compared for determining zinc in serum by flame atomic absorption spectroscopy. TPA also significantly increased the hexosamine concentration in both gastric corpus and antrum. For the first time in Austria, nine recommendations on nutrition, beverages and lifestyle for patients with gout and hyperuricemia were defined for everyday practice, as education material for patients and updated information for physicians.

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The purposes of this study were to develop a taxonomy for detection of errors related to hypertension management and to apply the taxonomy to retrospectively analyze the documentation of nurses in Advanced Practice Nurse (APN) training. Its emotional impact alone is pervasive and characterized by catastrophic losses of health, employment, independence and friends or loved ones. Therapy with factor IX concentrate resulting in DIC and thromboembolic phenomena. However, absorption experiments indicated that cl.18-5 did express near normal levels of these specificities, suggesting an alteration in the orientation or topographical distribution of these determinants. Administration of probenecid was partly intravenous (1 g) and partly oral (4 g).

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Patients with bleeding complications reveal significant lower nadir levels of fibrinogen than patients without bleeding complications. Replication error, mutator phenotype of mismatch repair gene is useful indicator to predict second primary cancers. Intra-amniotic use of urea and prostaglandin F2 alpha to induce labour in pregnancies complicated by death of the fetus. Double antiplatelet therapy duration: standardize or personalize? We proposed that tyrosine kinase inhibitors, imatinib or INNO-406, may restore CXCR4 expression and cause the migration of CML cells to bone marrow microenvironment niches, which in turn results in acquisition of stroma-mediated chemoresistance of CML progenitor cells.

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This is an observational database study conducted in a tertiary care center. Hybridomas representative of Group I (T15-like) and Group II (non-T15-like) antibodies utilize distinct VH genes. Complete sequential regeneration of graft-vs.-host-induced severely dysplastic thymuses. The outcome of our pregnancies involves one ectopic, one miscarriage and one normal term pregnancy.

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The absence in human serum of a ribonuclease that hydrolyses double stranded RNA. Using the LCA-immobilized resin, it was possible to purify pol beta from a mixture of proteins.

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The LD50 for oxygen debt is shown to be 113.5 mL/kg, 12.9 mmol/L for lactate, and -18.8 mmol/L for base excess (BE). Individuals carrying rare recognition cues would benefit less from social interactions than individuals with common cues, leading to loss of the genetic-cue diversity. A case of supplemental maxillary deciduous canines is described in a ten-year-old Saudi boy. Identification of a high molecular weight trans-membrane protein in mouse L cells.

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No nasal or respiratory tract tumors were produced by lifetime exposure of 100 rats to 10 ppm. We estimated odds ratio for choosing dual practice and the effects of dual practice on public working hours using different versions of mixed models.

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For this reason, physician awareness of contemporary injury patterns is the first step toward safer automobile design. These clones were used to analyze Northern blots containing RNA from uninduced and differentiated cells. The results are interpreted as reflecting the importance of the orbitofrontal cortex in olfactory discrimination. However, intraperitoneal administration of loperamide oxide following its incubation with the contents of the intestinal lumen under aerobic conditions resulted in an effective inhibition of fluid secretion.

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The ACL of 21 adult mongrel dogs was replaced with a knitted dacron velour prosthesis. Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Correlations among ultrasonographic and microscopic characteristics of prepubescent ram lamb testes.

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In addition, pacing from close to the A-V node also resulted in fusion beats characterized by absence of delta waves with (pseudo) normal QRS complexes and short H-V intervals. Characterization of canine monocytes in vitro: increased receptor activity for Fc, C3, and heterologous erythrocytes. Wide-field neurons in somatosensory thalamus of domestic cats under barbiturate anesthesia.

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The pattern and course of depressive symptoms and anxiety following DBS in PD is not clear, although both seem to improve in the short-term, especially depression following STN-DBS. Physical exercise in rats provokes an increase in plasma glucagon and free fatty acid concentrations. Obesity is defined as the accumulation of excess adipose tissue resulting from various metabolic disorders. Human TLR2 is expressed on the cell surface in a variety of cells, including monocytes, neutrophils, and monocyte-derived, immature dendritic cells (iDCs), whereas the expression profile of TLR6 in human cells remains obscure. Finally, we exemplify this approach by creating a testing data server that supports both FHIR resources and archetypes.

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Sera containing antibodies to both Sm and RNP reacted with all the four polypeptides. Tests staged on non-anesthetized cats demonstrated that the symptoms of the inhibited behaviour of the animals following introduction of diazepam and chlordiazepoxide are attended by hypertension, tachycardia and an increased intensity of pressor vasomotor reflexes.

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Single doses of methyldopa (750 or 1000 mg) significantly increased serum prolactin levels, peak concentrations occurring four to six hours after drug administrations. We review the key regulators of cellular senescence and recent in vivo evidence which supports p53-dependent senescence induced by short telomeres as a potent tumor suppressor pathway. Light spots of 10sec duration were focussed on the center of the receptive field under 1cd/m2 adaptation luminance by diffuse light.

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Improvement of four patients with HIV-1 related symptoms after hyperimmunization with killed poliomyelitis (Salk) vaccine. Treatment results in 1,080 patients with carcinoma of the tongue Only two patients (9 percent), one with cirrhosis and another with an undiagnosed pleural effusion, had a recurrence of the effusions.

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The periodic absence of detectable zona-reactive antibodies in zona positive mares suggests that multiple sampling may be required to eliminate the possibility of false negatives. These potentiating effects of dexamethasone on epinephrine-stimulated lipolysis were completely inhibited when the adipocytes were preincubated with the steroid and verapamil which inhibited hormone-induced calcium influx into the adipocytes. Furthermore, it was also shown that some of the antiepileptic drugs could potentially be responsible for additionally increased lipid peroxidation. Although home PN (HPN) is a lifesaving therapy, patients may, over the long term, be at risk for liver, bone, and immune dysfunction. In this review we summarized the available information concerning the icm/dot type-IVB secretion systems by comparing the two bacteria that possess this system, the proteins components of their systems as well as the homology of proteins from type-IVB secretion systems to proteins from type-IVA secretion systems.

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Disruption of cytoskeleton by cytochalasin D prior to treatment with TNF-alpha led to increase of p65 nuclear translocation. Ten healthy male volunteers of normal weight received 30 mg of D-fenfluramine, a putative selective releaser of 5-hydroxytryptamine (5-HT), and placebo by mouth in balanced order at a 1 week interval after a light breakfast. A total of 6,641 problem contacts, averaging 229 per student, were reported over a three-year period. The effects of polyamines and polyamine inhibitors on rat sciatic and facial nerve regeneration. Ultrastructure of sarcoballs on the surface of skinned amphibian skeletal muscle fibres.

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Computerized search of MEDLINE, EMBASE, BIOSIS, and CancerLit through March 2003 and reference lists of retrieved studies and review articles. A total of 219 patients with disease visualized on computed tomographic scan (recurrent or metastatic disease) or with negative or equivocal computed tomographic scan and rising carcinoembryonic antigen serum levels (occult group) received technetium Tc99m-labeled 88BV59 intravenously. Conical vitreous carbon implants were placed in fresh, second, and third premolar extraction sites, and the sites were allowed to heal for periods of 2 to 8 weeks prior to restoration with cast gold crowns. Plasmid DNA has been efficiently photocleaved by sodium pheophorbides (Na-Phdes) a and b with visible light even in the absence of oxygen.

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Increased platelet aggregability, and a reduced capacity of vascular endothelium for prostacyclin generation, may also be associated with insulin resistance. Proceedings: The results of artificial insemination with frozen semen. Computerized tomagraphy of the head--Part V: Cerebrovascular disease.

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But even in the area most extensively examined, the correlation between plasma level and clinical response, the results have been conflicting. Since it has been documented that homozygous mice fail to develop functional gonads, apparently due to insufficient production of gonadotropin, it is likely that the compromised development of the specialized submandibular glands, and, consequently, the male salivary protein pattern, is a result of decreased testosterone production. Parent and family impact of raising a child with perinatal stroke. Microvilli were observed on the cellular surface toward the tubal cavity. To evaluate the antiemetic effectiveness and side effects of adding low-dose droperidol to morphine delivered via a patient-controlled analgesia (PCA) device.

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On the basis of experience in the fields of AIDS, BSE, SARS and bird flu, this study discusses the strong and weak points of governance procedures for health risks. These results support recent histopathologic data on commotio retinae, which revealed moderate photoreceptor outer segment disruption and retinal pigment epithelium damage. The Southern transfer hybridisation technique was used to test mononuclear blood cells for hepatitis B virus DNA. A comparative study of talampicillin and ampicillin in general practice.

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We used an adapted EPPI-Centre mixed-method systematic review design with narrative summary, thematic and narrative synthesis. Cigarette smoking slows gastric emptying and as a consequence delays alcohol absorption. The offspring of schizophrenic parents in a North Swedish isolate. We assigned each patient a final cystinuria phenotype at 3 to 4 years. Variability in DNA measurements in multiple tumor samples of human colonic carcinoma.

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Rats with deoxycorticosterone-induced hypertension also showed a significant blood pressure fall. This paper describes the effect of the organophosphorus compound, the oxygen analogue of ronnel (OAR), on the activity of some membrane-bound enzyme systems in the brain mitochondria of developing, young-adult, and old rats. The results of double-inhibitor and uncoupler-inhibitor titrations have been simulated and analyzed with a linear model of delocalized protonic coupling using linear nonequilibrium thermodynamics. The efficacy of oral celecoxib for acute postoperative pain in face-lift surgery.

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Male rat fetuses treated with hCG at the end of gestation failed to show an increase in serum testosterone (T). The assignment of backbone resonances and the secondary structure determination of the Cys 10 Ser mutant of enzyme IIBcellobiose of the Escherichia coli cellobiose-specific phosphoenol-pyruvate-dependent phosphotransferase system are presented. The diagnosis of dementia in elderly Gujaratis was stable at follow-up with concurrent evidence of decline. Some even argue that PCI of bifurcation lesions should no longer be considered as being complex. Antibacterial effect of tea-tree oil on methicillin-resistant Staphylococcus aureus biofilm formation of the tympanostomy tube: an in vitro study.

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The use of glucose-free or glucose-poor dialysis solution presents a high risk of intradialytic hypoglycemia in diabetic renal patients, especially in those with presumed better glycemic control. This is also the first report that demonstrates ankylosis of impacted teeth in dysosteosclerosis.

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Pattern of expression of CD45 RA/RO isoformic antigens in acute myeloblastic leukemia cells. These data highlight the importance of assessment and documentation of HBV vaccination series among health sciences students prior to direct patient care activities. We attempted to define the minimum blood volume and bacterial concentration required to obtain a positive blood culture with the use of placental blood and an in vitro technique. Early parental loss may represent both environmental and genetic risk factors for bipolar affective disorder. Despite several polysomnographic studies on periodic leg movements (PLM) in healthy sleep, data on the prevalence and characteristics of periodic arm movements (PAM) in normal subjects are lacking.

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These findings show the same changes as found in the course of pregnancy in women. A cDNA probe utilized for collagen was Hf677 (a clone of human type I collagen alpha 1 chain). Values for total body sodium and chlorine obtained in the present study were compared with values previously reported in the literature.

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It is not known whether a Mastomys kallikrein processes and binds to nerve growth factor (NGF) as in mouse submandibular gland. Content chunks are represented as Flashcards that hold knowledge and open ended questions. Reproductive hormone and ovarian changes in cows with ovarian cysts.

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The continuously firing components initiated at feeding maintain a high level for 5 days indicating release of other brain neurosecretions. Ultrastructural changes in the upper small intestinal mucosa in patients with cholera. A slower hydrolysis is noted in the first peak after TAA treatment. Transient up-regulation of P-glycoprotein reduces tacrolimus absorption after ischemia-reperfusion injury in rat ileum. An IBM-PC based data collection system for recording rodent sexual behavior and for general event recording.

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Insulin signaling, lipid metabolism and the hepatic UPR may impact VLDL production, particularly during the postprandial state. It exhibited, on average, a 35-fold reduction in run time for a set of rigid impacts.

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The effect of nicotine activity is insulin resistance leading to lipid disorders which are risk factor for atherosclerosis. However, the efficacy of HER2/neu-targeted therapy in biliary cancers is unknown. High expression of the Glut1 glucose transporter in human brain hemangioblastoma endothelium.

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alpha-Chain contacts in the polymerisation of sickle haemogloblin. We hypothesized that primary porcine adipose tissue-derived stem cells (ASCs) nucleofected with plasmid containing recombinant human bone morphogenetic protein-6 (rhBMP-6) could induce bone formation and achieve spinal fusion in vivo.

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Different methods for incorporating active agents on nanofibers and controlling their release mechanisms are also reviewed. Release of interferon-induced translation inhibition by tRNA in cell-free extracts from mouse erythroleukemia cells. A major requirement for efficient energy transfer process is the proper arrangement of donors and acceptors in a few nanometers in length scale.

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It has been suggested that by expression of FasL, BCC cells may evade the attack of Fas-positive immune effector cells allowing the tumor to expand. Manual contouring and registration for radiotherapy treatment planning and online adaptation for cervical cancer radiation therapy in computed tomography (CT) and magnetic resonance images (MRI) are often necessary.

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These results have important implications for individuals living and aging with HIV-1 infection. Also, MECCF inhibitory profile was found comparable with toxicant group (Paracetamol 2g/kg, p.o.). Pain caused by cancer in the pelvis and sacrum is difficult to control using standard methods. The aim of this study was to investigate the clinical usefulness of provocative diagnostic tests, in patients with partial-thickness tears of the supraspinatus (SST) tendon. We used mixed additive models to elucidate the variation of Leq by diary-based information, baseline characteristics and time-invariant variables like long-term noise exposure.