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Ketolef (Ketoconazole)
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Ketoconazole

Ketolef is active against Candida spp., and Cryptococcus neoformans. However, its activity is limited compared to that of fluconazole and itraconazole. Furthermore, due to its limited penetration to cerebrospinal fluid, it is clinically ineffective in meningeal cryptococcosis. Its activity against the dimorphic moulds, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Sporothrix schenckii, Paracoccidioides brasiliensis, and Penicillium marneffei is favorable. However, fluconazole and itraconazole are at least as effective as Ketolef against these fungi and are safer. Thus, Ketolef remains as an alternative second-line drug for treatment of infections due to dimorphic fungi. Ketolef is not recommended for treatment of meningeal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides immitis due to its limited penetration to cerebrospinal fluid. Ketolef is also active against Pseudallescheria boydii and is a good alternative for treatment of pseudallescheriasis. It is also effective in pityriasis versicolor. Ketolef has practically no activity against Aspergillus spp., Fusarium spp., and zygomycetes order of fungi.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Monoclonal antibodies point to carbohydrate structures as tumour-associated antigens. Although a considerable number of grade 1 and 2 cases in both systems had PNM, fulfilling the criteria for grades 1 and 2 CNFS, it does not perfectly predict PNM. Letter: Hypoglycaemia in children undergoing adenotonsillectomy.

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Fracture union in closed interlocking nail in humeral shaft fractures. Blinding eye diseases caused by neovascularization of the retinal tissue are the leading cause of blindness in Western societies. Notably spermatogonia, capillary endothelium, connective tissue and peritubular fibroblasts are rarely involved. The role of alpha- and beta-adrenoceptor subtypes in mediating the effects of catecholamines on fasting glucose and insulin concentrations in the rat. Common afflictions diagnosed by arthroscopy include chondromalacia, meniscal lesions, osteoarthritis, cruciate ligament injuries, chronic synovitis and loose bodies.

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Oligonucleotide primers, based on the published amoA sequence from Nitrosomonas europaea, were used to amplify DNA from pure cultures of Nitrosomonas europaea, Nitrosomonas cryotolerans, and Nitrosococcus oceanus and from bacteria in seawater collected offshore near the Florida Keys. A cluster of genes involved in polysaccharide biosynthesis from Enterococcus faecalis OG1RF. ICI 182,780 eliminated the effects of estrogen on brain edema and brain blood barrier permeability. Tissue homogenates and bronchoalveolar lavage fluid from patients with IPF both demonstrate elevated IRAP content compared with that in normal subjects. Influence of magnetically-induced E-fields on cardiac electric activity during MRI: A modeling study.

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Contribution to the problem of extramedullary and asecretory forms In addition, 18 days after treatment, significant macrophage tumoricidal activity was observed only in the ADM/Lip-treated group. Microbiological testing of commercial ice cream in Messina as required by the Ministerial Ordinance of 11 October 1978

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None of the mammalian splicing factors that have been cloned corresponds to the yeast pre-messenger RNA splicing factors, the PRP proteins. Last decade has seen quick developments in the understanding of a new type of T lymphocytes, Th17 cells.

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High frequency of K-ras mutations in spontaneous and vinyl carbamate-induced lung tumors of relatively resistant B6CF1 (C57BL/6J x BALB/cJ) mice. A 10 days Leucotrofina or Timolimfotropina administration induced in Wistar rats a rise of glycemia and liver glycogen content, and a decrease of glycogen-phosphorylase a activity.

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A subepicardial space appears early and it is populated by mesenchymal cells which seem to proceed at least partly from the epicardium. Nineteen out of 21 consecutive patients could be operated with this technique.

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Furthermore, covalent inhibition, which already led to the first high-quality probe for JNKs, might be further exploited for gaining selectivity and in vivo efficacy. Expression profiling studies showed significant alternations in expression of calcium channels and pumps in testes and concurrently Tmem203 deficient spermatocytes demonstrated significantly altered calcium handling. Methods are described for the in vitro generation and detection of antibody-secreting cells (PFC) from channel catfish. The magnitude of the blast cell response observed in efferent lymph in the case of grafts exchanged between cotwins was generally intermediate between that observed in responses to allografts and control autografts. Two of the children with precocious puberty had hypothalamic hamartomas, one had an optic glioma, and one had a history of hydrocephalus.

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Comparing Genomic Profiles of Women With and Without Fibromyalgia. Contribution to the experimental study of artificial respiration by the rocking bed Cigarette smoking (CS) and air pollution can both alter autonomic cardiac function, yet little has been reported on their combined effect on cardiovascular dysfunction. Removal of cell surface sialic acid by neuraminidase treatment unmasked the lectin receptor sites of invasive hybrids to the level of the corresponding sites of non- or low-invasive cells. Plasma beta-thromboglobulin (beta-TG) levels were also measured before and after each run.

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Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and mean age of onset of late-onset familial and sporadic Alzheimer disease. Predictors of subsequent schizophrenia spectrum disorders in vulnerable adolescents. Assessment of the techniques used for the repair of stress urinary incontinence (SUI) and anterior vaginal wall prolapse, as well as the incidence of intraoperative and postoperative incidents and complications.

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