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Exposures to cotton dust and endotoxin were estimated using area samples collected at each survey. Susceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cells. Cell death in vitro was quantitated using the chromium-release assay. The survey included programs housed in diverse institutional settings. Immunoassay of SF in plasma from subjects with conditions related to altered GH levels indicated that serum SF levels were not GH-responsive to any marked degree.

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The compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a relatively selective neurotoxin that destroys dopamine (DA)-containing nigrostriatal neurons. Here we examine this question by profiling an additional 104 primary prostate cancers and updating the initial 168 patient cohort with long-term clinical outcome.

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The extent of binding of menadione to DNA in vitro, was markedly decreased by inclusion of the hepatic cytosol fraction, or reduced glutathione, in the incubations. Bovine spinal anomaly with anatomical similarities to complex vertebral malformation.

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Here we report a kinetic analysis of fluorescent guanine nucleotides binding to EFL1 alone and in the presence of SBDS using fluorescence stopped-flow spectroscopy. The survival of both cell types was enhanced by purified recombinant human granulocyte-macrophage CSF and partially purified preparations of the native molecule, CSF alpha. Clinical observations on a case of aberrant suprahyoid thyroid with malignant degeneration, surgically treated Downregulation of endothelin receptor mRNA synthesis in C6 rat astrocytoma cells by persistent measles virus and canine distemper virus infections.

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Menstrual phase was determined through questionnaires and objective measurements of basal body temperature (BBT) spikes over a 1 month period. Data abstracted from the medical records included demographics, diseases, treatments, and outcomes. In an in vivo experimental metastasis assay, which determines mainly the later steps of the metastatic migration process (extravasation from the bloodstream and then growth into pulmonary tumor), none of the peptides introduced by i.v. The objective of this work was to ascertain the influence of copper on the corrosion mechanism of palladium-silver alloys. With DGD embedment free technique and electron microscopic autoradiography, the newly synthesized virus DNA is found to be associated with intermediate filaments.

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Tyrosine kinases comprise the largest group of oncoproteins, a fact that underscores the importance of reversible tyrosine phosphorylation in the regulation of essential cellular functions. Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points.

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A shift in the hepatic metabolism of fatty acids, leading to greater triacylglycerol formation at the expense of other processes is therefore suggested. The dental status of 16 children who had been treated with bone marrow transplantation (BMT) for serious bone marrow diseases was followed for up to 6 years. Here we show that Sestrin2 physically associates with Unc-51-like protein kinase 1 (ULK1) and p62 to form a complex in which both Sestrin2 and p62 become phosphorylated by ULK1 at multiple sites.

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Effect of freezing and storing on the biological properties of macrophages. Although the prefrontal cortex may also be a site for the disruption of smooth pursuit eye movements (SPEM), the most substantially described psychophysiological marker for schizophrenia vulnerability, no relationship of SPEM to dopaminergic activity has been demonstrated. Assessment of recovery: with special reference to a study with post-operative cardiac patients.

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We have detected a HeLa cell factor, termed E2 promoter binding factor (E2F), that appears to mediate the transcriptional stimulation of the viral E2 promoter. The theory behind medicine is leaking and draft comes through the windows NKCF are released into the supernatant of co-cultures of murine spleen cells and YAC-1 stimulator cells, and their lytic activity is measured against YAC-1 target cells. Current methods of urologic examination of patients with uterine myoma

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Because of ethical concerns in human clinical practice, this study has been performed only on immature oocytes and corresponding cumulus cells, which are usually discarded during in vitro fertilization procedures. The Ad protein, DNA polymerase, and pTP-dCMP complex-forming activities sedimented in a glycerol gradient as a single peak with an apparent molecular size of 180,000 daltons. These data implicate glycation-induced inactivation of CD59 as a factor contributing to anaemia in type 1 diabetes.

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The pathways of endocytosed transferrin and secretory protein are connected in the trans-Golgi reticulum. Physician recruitment problems and sudden population growth placed a severe strain on several New Hampshire communities until civic and hospital leaders pooled resources to develop combined emergency/outpatient satellites. The vasopressor effect produced by isolated intraspinal hypertension may be the consequence of ischaemia of the spinal vegetative structures. In five of 32 joints judged normal on plain film radiographs, significant pain relief was experienced following anesthetic injection, resulting in a change in the proposed surgical procedure.

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The developmentalist and the study of biological risk: a view of the past with an eye toward the future. On the studying of laboratory animals, the humoral response by the antibody formation against S.typhi and the cellular response by PPD tuberculin of vaccinated animals with BCG, were examined.

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The transmitted wave front of these rods is corrected by magnetorheological finishing to achieve nearly diffraction-limited output performance with frequency-doubled pulse energies up to 1.8 J at 5 Hz. Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody. Effect of anti-inflammatory agents on accelerated granuloma formation in rats.

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Antibody response to immunization with Haemophilus influenzae type b polysaccharide vaccine in children with cancer. Immunoelectron microscopy was employed to examine the temporal expression and localization of two proteins involved in baculovirus polyhedron assembly (polyhedrin and p10) of Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus (OpMNPV) in infected Lymantria dispar cells.

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4-Aminopyridine sensitivity of the transient outward current was in the low millimolar range. The inability of the sp(3) boron in MIDA boronates to stabilize an adjacent radical makes possible the efficient addition of a wide array of xanthates to vinyl MIDA boronate, leading to highly functionalized and diverse aliphatic organoboron structures. The metrics used within the tools appeared to focus primarily on the sensory aspect of pain, with no study clearly discriminating between the sensory and affective components of pain. Papua New Guinea, Solomon Islands, and Ghana should be the focus of initial efforts at implementing the WHO yaws eradication strategy.

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Distribution of proteoglycans antigenically related to corneal keratan sulfate proteoglycan. Displacements occurring in the TMJ due to orthodontic elastics will be in the order of 20 mum which is between one and two orders of magnitude smaller than could be detected by radiography. The elucidation of the primary structure of these antigens made possible the generation of synthetic and recombinant proteins that are being extensively used in experimental immunizations against the infection. Value of an ergometric test for the assessment of cardiac failure

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It occurred after a lag phase when the ratio of MgATP to subfragment 1 concentrations was greater than 0.5. Antagonism by baclophen of the d-amphetamine-induced disruption of a successive discrimination in the rat. A case is presented of genital prolapse occurring during pregnancy in a patient with multiple congenital urogenital defects. A comparison of CTA and conventional arteriogram was performed in 53 patients undergoing evaluation for carotid artery stenosis. Ratings of perceived exertion (RPE) as an index of aerobic endurance during local and general exercises.

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These granules often showed focal to complete degeneration, occassionally being continuous with a myelin figure. We report a case of symptomatic, disseminated intestinal, urinary, nasal, and ocular microsporidian infection in a patient with AIDS. A comparison of immobilized pH gradient isoelectric focusing and strong-cation-exchange chromatography as a first dimension in shotgun proteomics. Since the functional outcomes of acute and experimental chronic spinal cord injury have been shown to improve with stem cell therapy, a case study was conducted to test if the application of stem cell also regenerates chronic SCI dysfunction. Antigenic heterogeneity of human colorectal cancer cell lines analyzed by a panel of monoclonal antibodies.

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Clinical features and outcomes of spinal cord arteriovenous malformations: comparison between nidus and fistulous types. ANP has potent effects on the cardiovascular system in conscious sheep, exerting its effect on blood pressure primarily by its action on the venous circulation and on cardiac output. When the clinical features and radiographic changes suggest a congenital abnormality of the tracheobronchial tree endoscopic examination can give useful information. Thus suggesting that 3-MA can reverse cancer MDR via depressing agent-efflux transporters.

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They are an ancient sensory apparatus for the cell, not just the multicellular organism, and they have been adapted to respond to all manner of stimuli, from both within and outside the cell. The motor nuclei of the glossopharyngeal-vagal and the accessorius nerves in the rat.

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All patients who underwent partial nephrectomy for relative or elective indications were without definite evidence of recurrent disease at last followup (over-all mean 36 months). However, the clarithromycin inactivation assay and knockout mutation analysis showed that the gene increased clarithromycin resistance in E. On Days 0-3 cells were most sensitive to cis-HP, since on Day 11, 8 days after removal of cis-HP, they were too scarce to be counted by the staining method. Liver ethoxycoumarin deethylase increased somewhat above the control level at the end of the exposures while hepatic glutathione decreased.

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We have determined the nucleotide sequence between the dam and trpS genes and show that it encodes two proteins with molecular weights of 24 and 27 kDa. Robust forms of the published Shanghai top 100 rankings are calculated and compared to each other. In summary, we report new facets of the endosomal escape process bearing relevance to antigen cross-presentation.

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Lithium-induced inhibition of Na-K ATPase and Ca ATPase activities in rat brain synaptosome. Breeding in all classes of livestock has moved from a purebred appearance orientation to a performance (either purebred or crossbred) orientation.

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The association noted between serum carotenoid levels and neovascular AMD supports the hypothesis that higher levels of micronutrients with antioxidant capabilities may decrease the risk of AMD. Some interneurones in this population are excited only by flexion, some only by extension, but others by both flexion and extension movements of the femoro-tibial joint. Holographic characteristics are presented of dyed red plastic involving beam powers ranging between 3 and 120 mW/cm2 and exposure times in the order of minutes. Since a stimulation of prostaglandin E2 secretion was also observed in presence of Il-1, we investigated the eventual role of arachidonic acid metabolites in the phenomenon. The treatment should be aimed at relieving symptoms arising from gut dysmotility (ideally using prokinetic agents), controlling abdominal pain (possibly with non-opioid antinociceptive drugs) and optimizing nutritional support.

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clonazepam, because of its more prolonged action, could be the drug of choice in controlling status epilepticus. In order to identify amino acids directly involved in progesterone binding to rabbit uteroglobin we have mutated Phe 6, Tyr 21 and Thr 60 by site-directed mutagenesis of the uteroglobin cDNA.

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Body fat in urban and rural male college students of eastern India. We have investigated the correlation between the molecular structures of various organic cations and their binding to rat small intestinal brush border membrane. No evidence for the expression of the progesterone receptor on peripheral blood lymphocytes during pregnancy.

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Mitral stenosis and mitral incompetence due to Libman-Sacks endocarditis with mitral valve replacement. In vitro investigations of the genotoxicity and mutagenicity of toxaphene were generally described in the literature, but they provided somewhat equivocal results. Electroconvulsive therapy: a life course approach for recurrent depressive disorder. Influence of acoustic reflex on acquisition of temporary threshold shift from short duration noise bursts.

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Studies on the fatty acid composition of tissue lipids in rats fed with a diet containing sunflower oil. Our ultrastructural study on the evolution of the sporulation septum during the early stages of arthrospore maturation in seven species of Streptomyces indicates correlation between the sporulation septum type and its evolution during the arthrospore maturation. Platelet morphology was grossly abnormal and electron microscopy revealed few, or absence of, alpha-granules. Little is known about the genes that control the embryonic erythroid program. Trimethoprim-sulfamethoxazole was bactericidal against two strains of S.

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However, 14 of the 174 patients had albinism, a well-known risk factor for skin cancer in black Africans. The respiratory inhibitors eliminated the inhibitory effects of the electron acceptors on the current generation from MFCs. In the developing kidney VEGF-expressing epithelial cells also express VEGF receptors. From those corrosion tests as well as XPS results, it can be suggested that the partially crystalline graphitic carbon surface facilitates the relatively more reduced surface of platinum.

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We found that LVA currents were unaffected when cells were incubated with beta-antisense, while HVA currents were drastically decreased. Alpha 1-antitrypsin level and the state of the respiratory tract in arc welders Hereditary internal anal sphincter myopathy causing proctalgia fugax and constipation. At 12-18 hr of hCG injection (about 2-8 hr after ovulation), the ova with surrounding cumulus cells lie free in a wide lumen, and the muscular tissue consists of only 2 or 3 layers of cells, arranged mostly longitudinally. Comparison of sodium amylosulfate and sodium polyanetholsulfonate in blood culture media.

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NiaA occurs as a single-copy gene ant its expression is regulated by the nitrogen source. Differences in onset timing between the vastus medialis and lateralis during concentric knee contraction in individuals with genu varum or valgum.

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In examining the migration of macrophages on to subcutaneously implanted coverslips in rats, it was found that coumarin (5-6 benzo-alpha-pyrone) and a preparation (Venalot) containing the former, very significantly increased the total macrophage number as well as the percentage of stimulation on the skin side of the coverslip. However, DEX did not reduce, but rather potentiated, IL-1 and TNF stimulated SAA production, indicating that these monokines do not require macrophage products to mediate their in vivo SAA inducer activity. Fifty-one patients (age range, 22 to 79 years) with descending thoracic or thoracoabdominal aortic disease had resection and graft replacement of the diseased aortic segments using hypothermic cardiopulmonary bypass and intervals of circulatory arrest in situations where the location, extent, or severity of disease precluded placement of clamps on the proximal aorta (8 patients) or (in 43 patients) when extensive thoracic (11) or thoracoabdominal (32) aortic disease was present and the risk for development of spinal cord ischemic injury and renal failure was judged to be increased.

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Treatment of bladder carcinoma in situ with mitomycin C: long-term follow-up. We studied three patients, one with acute T-cell leukemia, and two with aplastic anemia.

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