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Genoxal (Cyclophosphamide)
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Cyclophosphamide

Genoxal is the generic name of the prescription drug Genoxal, a chemotherapy drug for people with certain cancers. It’s prescribed for non-Hodgkin lymphoma, Hodgkin lymphoma, multiple myeloma, small-cell lung cancer (SCLC), leukemia, ovarian cancer, retinoblastoma, neuroblastoma, and breast cancer. Genoxal is sometimes used to treat kidney damage. Doctors may also prescribe Genoxal off-label to treat some kidney infections; systemic sclerosis or scleroderma (hardening of the organs and body tissues); and juvenile arthritis. The Food and Drug Administration (FDA) approved Genoxal as Genoxal in 1959, and Baxter International, Inc. manufactures it.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit. (3) Average pressure values demonstrated by the geriatric hospitalized subjects were roughly equal to those of the younger subjects (roughly 70mmHg).

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Filament formation is distinct from agar penetration in both haploids and diploids. This software is intended to provide a useful tool for general-purpose encoding of protein sequences and structures for applications is protein classification, similarity analyses and function prediction. Plasma concentrations of estradiol in women suffering from schizophrenia treated with conventional versus atypical antipsychotics. Effects of zinc on the cytoskeletal proteins in the central nervous system of the rat. Cystic adenomatoid malformation is a rare congenital pulmonary anomaly.

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Impacts of Maternal Nutrition on Vascularity of Nutrient Transferring Tissues during Gestation and Lactation. Long-term effect of lithium on the uptake of 5-hydroxytryptamine by human platelets. Inoculated animals were able to reject otherwise lethal tumors several months following the original DNA inoculation protocol. Mitochondria are highly dynamic, except in adult cardiomyocytes.

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The findings indicate that a life-prolonging effect of methionine on Z. Indomethacin (5 mg/kg i.v.) doubled the direct dilator effect of PGI2, and increased the sensitivity of the artery to 5-HT (by 11.5-fold) and to U46619 (by 2.8-fold).

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The role of lenalidomide in the management of myelodysplasia with del 5q. The medial subnucleus (m)nTS at levels rostral to the obex, the primary site for the termination of gastrointestinal afferents, showed substance P immunoreactivity in moderate amounts and weak immunoreactivity for all the other neuropeptides. Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient. To determine whether the hybrid promoter could elicit RMS-specific cytotoxicity, a mammalian expression vector containing the herpes simplex virus thymidine kinase (HSVtk) under control of the hybrid myoD enhancer/SV40 promoter was constructed. Chemokine ligand 12 and chemokine ligand 7 have been identified and investigated in multiple studies for their role in cellular trafficking in the setting of tissue regeneration.

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RNA interference (RNAi) is an evolutionarily conserved mechanism for silencing gene expression. Surgical implants are exposed to severe working conditions and therefore a wide range of failure mechanisms may occur, including fatigue, corrosion, wear, fretting and combinations of them.

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coli from cases of diarrhoea (680 from pigs, 187 from cattle and six from sheep). The results suggest that our cognitive control can cope with the interference posed by pleasant distractors as well as with the interference posed by neutral stimuli. Currently, only 25 countries, including the United Kingdom, the United States, and Australia have schemes for artificial water fluoridation. All cases had a high ventricular mass, but the critical value of ventricular mass or the ratio of mass to left ventricular enddiastolic volume were also inconsistent. Effect of family structure on the dental caries experience of children.

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The employees were classified by job functions: (i) line operators were employed full-time on the production line, (ii) non-exposed employees did not work in production, and (iii) the remainder of the employees were classified as non-line operators. A group of 90 feeder calves was accidentally exposed to lead for approximately 30 days. Effects of indomethacin in vivo and in vitro on the metabolism of PGF2alpha increased by estrogen were also examined.

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Ultrastructural and phenotypic changes in Langerhans cells induced in vitro by contact allergens. The rise in plasma FSH concentration was greater in males than in females at all ages, although, a larger increase was observed in females spayed at 5 or 10 days of age than at other times.

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Incidence of emboli with cloth-covered Starr-Edwards valve without anticoagulation and with varying forms of anticoagulation. We hypothesized that EP4 expression is regulated in the rat cervix to coincide with cervical ripening. In recent years, great progress has been made in the development of computer-based technologies that support the manufacturing industries.

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MT-2 cell tropism of human immunodeficiency virus type 1 isolates as a marker for response to treatment and development of drug resistance. Efficacy of patient selection strategies for carotid endarterectomy by contrast-enhanced MRA on a 1 T machine and duplex ultrasound in a regional hospital. However, after interferon was removed, protein modifications appeared with increasing passage number. Emphysematous pyelonephritis: successful treatment with percutaneous drainage. In 6- and 12-week-old SLD strain cockerels, the PHA:Con A response ratio was significantly (P less than 0.05) lower than in K strain cockerels.

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The availability of large amounts of stable enzyme from the two microbial sources has facilitated the recent studies. Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. The cost-effectiveness of voluntary counseling and testing of hospital inpatients for HIV infection. It is possible that the toxification of scallop is partly due to the toxins already accumulated in Protogonyaulax cells, and partly due to incorporation of this precursor, which releases the toxins as a result of enzymic processes in the shellfish. A major challenge is that of unraveling the molecular regulatory networks from massive and heterogeneous datasets.

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An 847-amplicon panel was designed with the RainDance DeepSeq system, covering most exons of 28 genes relevant to acute myeloid leukemia and myeloproliferative neoplasms. Comparative study between procaterol and salbutamol in mild to moderate bronchial asthma Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES).

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A comparative preference study between xylometazoline nasal dose spray (Otrivin) and oxymetazoline single-dose pipettes (Nezeril). Cefoperazone was the most active drug against Pseudomonas sp., Achromobacter xylosoxidans, Flavobacterium meningosepticum. We compared the G-protein requirements for coupling of human and chicken m2 and m4 muscarinic acetylcholine receptors (mAChRs) to inhibition of adenylyl cyclase, using a luciferase reporter gene under the transcriptional control of a cAMP response element as a sensitive monitor of intracellular cAMP levels.

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The issue of integration in neural networks is intimately connected with that of consciousness. Isolation of nascent fibroin peptides from the posterior silk gland of Bombyx mori.

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Implantable cardioverter-defibrillator therapy in arrhythmogenic right ventricular cardiomyopathy: a role for genotyping in decision-making? injection of HM-PAO (hexamethyl propylene amine oxime) labelled with 99m Tc, the uptake of which by various cerebral regions is visualised via SPECT.

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Surface plasmon hurdles leading to a strongly localized giant field enhancement on two-dimensional (2D) metallic diffraction gratings. These changes were associated with reduced synaptic vesicle mobility, with no alterations in synaptosomal morphology as evidenced by electron microscopy. Fine structure of Leucocytozoon caulleryi during microgametogenesis and fertilization.

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Depressive symptoms were found at the same prevalence rate in both blue-collar and white-collar workers, which suggests that health measures for depression are necessary for both types of worker. According to our study and recent reports from other Middle East countries, we suggest GJA12 gene mutations are common in this area, but we didnot find any previous report about this new mutation (c902-918Del). The effect of magnesium on apatite nucleation by Bacterionema matruchotii proteolipid was determined. This article outlines the tenets and basic data critical for the management of prosthetic graft infections.

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Gastric carcinoid tumors in multiple endocrine neoplasia-1 patients with Zollinger-Ellison syndrome can be symptomatic, demonstrate aggressive growth, and require surgical treatment. The juxtaposition of DNA sequences homologous to pUNC724 and ribosomal DNA sequences presumably occurred within the past thirty-five million years, following the divergence of the lines leading to man and the New World owl monkey, Aotus trivirgatus--pUNC724 is not syntenic with the single chromosome containing ribosomal DNA sequences in the owl monkey.

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The portal blood flow, and especially the splenic venous blood flow, was less during operation than before operation. The choice of the approach employed consequently depends on the clinical question at hand and the availability of sufficient clinical data. As natural compounds of several foods such as vegetables, fruits and red wines, they are estimated to be widely ingested by humans. Based on the data from 2012, the estimated costs for NT-proBNP tests and echocardiographies per county were reduced by EUR 300000/100000 inhabitants with the 300 pg/mL cut-off and EUR 350000/100000 inhabitants with the 400 pg/mL. These data confirm an increase in maternal weight gain before and during pregnancy.

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Regulation of the cytotoxic T lymphocyte response against Sendai virus analyzed with H-2 mutants. injection of 1 microg recombinant(r) gp120 into gp120-immunized human CD4-transgenic mice (huCD4 Tg), which express huCD4 on both T and B cells, results in T and B cell depletion in peripheral blood and lymphoid tissues. Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B). We have investigated the effects of intrathecal (i.t.) N-methyl-D-aspartate (NMDA) and an NMDA antagonist D-2-amino-5-phosphonovalerate (APV) on spontaneous and evoked activity in rat dorsal horn convergent neurones. Application of this approach should result in near elimination of the spread of cancer in children with MCT.

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The role of fibrinolysis in the pathogenesis of the haemorrhagic syndrome produced by virulent isolates of African swine fever virus. Although this complication occurs rarely, the entity should be kept in mind in patients with infarcts and a remote source of infection. The management of research in aging: a case study in science policy. Section of the brain stem caudally, in the upper pons or at the inferior colliculus, also causes a dissociation of electrocortical activity from breathing movements, which become almost continuous. Results are discussed in relation to flow visualization observations and the behaviour of flow in curved vessels.

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The functional organization of anti-predator behaviour in the pied flycatcher: a study of avian visual perception. The purpose was to evaluate to what extent mortality trends could be explained by changes over time in the population load of conventional cardiovascular risk factors. Footedness Is Associated With ADHD Symptoms in the Adult General Population. Chlorin e6 (Ce6), a photosensitizer, was conjugated to CD44 antibody in order to target PC-3, a prostate cancer cell line. Both these patients underwent a ventriculo-peritoneal (VP) shunt surgery prior to the tumor excision.

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Soft tissue injuries are relatively common after blunt neck trauma, because of its complex anatomy, many vital structures can be compromised. The mean value of 3 different, commonly used, surface roughness parameters was calculated for the edge measurements. These defects may play a role in the prolonged bleeding time and the clinical bleeding observed in patients with uremia. Cells were cultured, exposed to proteasome inhibitors (bortezomib, ALLN, MG-132 and epoxomicin) and then assayed for cell cycle and cell death analyses.

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Molecular pharmacological differences between carminomycin and its analog, carminomycin-11-methyl ether, and adriamycin. T cell rearranging gene gamma: diversity and mRNA expression in fresh cells from T cell acute lymphoblastic leukemia.

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Furthermore, chronic mouth breathing may initiate and/or contribute to this disease. Using a culture of human mesenchymal stem cells (MSCs) as a model, we showed that MSCs can be seeded and grown in the albumin tissue scaffold. Eight genome RNA segments are present in both normal and von Magnustype influenza virus preparations and all species are transcribed by the virion-associated polymerase. The nuclear receptor Steroidogenic Factor 1 (SF1) plays a critical role in the development of the adrenal gland and gonads, and in sexual differentiation.

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Whether the injury is blunt or penetrating depends on factors of force, surface and time. This study replicated a previous demonstration of prism-induced aftereffects in 5-9-month-old infants. The objective of treatment is to effect a neuromuscular release of articulate for acne results with spironolactone the mandible. A sample size calculation was performed and a sample of 82 elderly Chinese with dementia were invited who were aged 60 or above, fit for periodontal assessment with probing and attended day-care centres.

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An amphipathic helical structure was predicted in the N-terminal region of MbeD as well as in the corresponding homologous proteins of ColA and ColK. Experiences in the decentralization of the medical welfare activities in the Turin commune On the basis of studies carried out mysoline dose in 23 (HLA) and 20 (GLOI) informative families, linkage between adrenal hyperplasia and locus B of HLA was confirmed, whereas that with GLOI was ruled out. Thrombin-induced fibronectin binding to rat platelets: relationship to other inducing agents. Although the brain monoamine systems have long been the focus of drug therapy for depression and anxiety disorders, current drug discovery has aimed at new molecular targets outside the monoamine systems to overcome these problems.

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While a prominent increase in the percentage of Pit-1/PRL, Pit-1/beta-luteinizing hormone and Pit-1/beta-follicle-stimulating hormone immunoreactive cells was observed in pregnant rats, the percentage of Pit-1/GH immunoreactive cells was strongly decreased. buspiron mylan 5 mg Anti-HBV vaccination before therapy with interferon (IFN) in chronic B hepatitis. The barA and sirA genes of Salmonella enterica serovar Typhimurium encode a two-component sensor kinase and a response regulator, respectively. Frontal affinity chromatography (FAC) is a simple but powerful method to analyze molecular interactions between an analyte and an immobilized ligand by calculating the extent of retardation of the elution front. However, there are infrequent studies karyotyping solitary osteochondromas.

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Inside and outside the liver: the challenge of hepatitis-associated aplastic anemia in children. Motive force of bacterol forte cotrimoxazol al the migrating pseudoplasmodium of the cellular slime mould Dictyostelium discoideum. GhNAP could rescue the delayed-senescence phenotype of the atnap null mutant. Most clients did not receive counselling on partner reduction or disclosure of HIV test results to partners.

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