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Kinesin, an essential motor protein that moves intracellular cargo along microtubules, walks like a person. The best therapeutic strategy to be applied in asymptomatic cases is discussed. Surgical management of total ulcerative colitis and familial adenomatous polyposis. An increase in the blood flow associated with normalization of cellular energy metabolism explained the decrease in brain edema. vera gel ethanolic extract at a dose of 300 mg/kg body weight per day to diabetic rats for a period of 9 days resulted in a significant reduction in fasting blood glucose and a significant improvement in plasma insulin.

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The analysis of autopsy data from 1928 to 1972 shows that the relative frequency of carcinoma of pancreas has undergone a threefold increase during the past 30 years. The clinical characteristics of special airway foreign bodies in children is different from ordinary foreign body, treatment of preoperative, intraoperative and postoperative is not fully equivalent to the ordinary foreign body.

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To obtain comparable effects, the concentration of CLP had to be about twice that of ELP. Some bone marrow macrophages from a variety of animal species synthesize a proliferation inhibitor which specifically inhibits the flow of murine CFU-S into DNA-synthesis.

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It was then demonstrated that these muscles have different and distinguishable actions on trunk movement, but act together in breathing. The hydrated PMEA analogues exhibited the different amounts of intermediate water. Therefore, this approach has the potential to be a new vaccine technology, in addition to its utility in other areas of research. A review of lysosomal membrane stability measured by neutral red retention: is it a workable earthworm biomarker? Aggregates of viral particles heavily coated with antibody were seen by immune electron microscopy (IEM).

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We present a case of multicentric low-grade gliomas and highlight their pathogenesis, imaging characteristics, and molecular signatures, with implications for clinical management. These effects suggest that AIB uptake by the human placenta and ACh biosynthesis catalysed by ChAc are related.

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Mutations that disrupt dimerization abolish actin assembly activity, suggesting that dimers are the active state of FH2 domains. PCNA-immunoreactivity in the uterus of rats after treatment with the antiestrogen tamoxifen.

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The place of indigenous and Western systems of medicine in the health services of India. Indications for and results of surgery in congenital aortic stenosis.

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Also the local dose rate at the position of the nuclei of the follicle cells is determined as a function of the follicle size. AC extract significantly improved the FFAs-induced steatosis without cytotoxicity and Caspase-3, -9, Bax and Bcl-2 were modulated profitably to HepG2 cells after AC treatment.

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Adjusted multivariable analyses suggest that therapeutic relationships, informal peer support and negative experiences related to staff may be important factors in accounting for greater satisfaction in crisis houses. Consideration of these lenses as an alternative to sutured posterior chamber IOLs for secondary or exchange implantation may be warranted for selected clinical indications. We have developed and internally validated multivariable preoperative models for the prediction of survival and major complications in patients with RCC who have a suprahepatic inferior vena cava thrombus. Cloning and characterization of the gene for beta-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker.

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The renal dopaminergic system is a potentially important regulator of sodium homeostasis and kidney function. Effect of acute uremia on insulin removal by the isolated perfused rat liver and muscle. The positive clones that competed with LBP for CD14 binding was obtained by screening. Back injury prevention in health care requires training techniques, exercise.

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Although molecular models for the structure of activation domains are not yet available, clues are emerging from mutational analyses of many activators. vinelandii diffract to angles corresponding to resolutions as great as 2.4 A and 3.0 A, respectively. Following removal of sizable craniofacial tumors, large defects in the dura of the anterior cranial fossa usually result. Bone scan in extraskeletal neuroblastoma with hot primary and cold skeletal metastases. Production of clones of homozygous diploid zebra fish (Brachydanio rerio).

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Coral resorption was also accelerated by growth factor and was replaced by histologically normal bone after two months. However, it is not known whether dietary salt influences retinal vasculopathy and if the renin-angiotensin-aldosterone system is involved.

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Effect of bicuculline application to the superior cerviclal segments of the spinal cord and the scratch reflex From research online and into company archives, relevant publications and information were identified. coli, and induced single bulge formation or filamentation of the cells around MIC levels. Therefore, either more sensitive end points must be developed to detect subtle changes due to chronic ozone exposure, or ways of selecting subpopulations that are especially sensitive to ozone must be devised. Moreover, we also studied the changes of outer mitochondrial membrane using synchronous fluorescence spectra.

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Fourteen years of high-dose CHOP (ACVB regimen): preliminary conclusions about the treatment of aggressive-lymphoma patients. SAS1 was found to be identical to CDC7, a gene which encodes a protein kinase required for the initiation of DNA replication. This review will present treatment pathways of CS complicating acute myocardial infarction, with a major focus on revascularization, intensive care unit treatment, and mechanical support devices. Late recovery was impressive, both in quality and lack of side effects, and all patients were considered fit for discharge from hospital within four hours of the operation.

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Apoptosis is upregulated in early myelodysplastic syndromes (MDS) and may contribute to the peripheral cytopenias commonly observed. Profiled agents, some of them marketed products, affect eicosanoid biosynthesis in ways that cannot be predicted from information on their intended targets. The internalized 125I-MCAF was progressively degraded and released into the culture medium starting at 30 min.

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Effectiveness of the smallpox virus (IC strain) vaccine and reactivity of the human body to this vaccine The indications for, advantages, and disadvantages of external rhinoplasty are considered from a pragmatic and philosophic point of view.

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The swelling disappeared after seven days of rest and antibiotic therapy. The study population consisted of 6817 participants drawn from the MONICA/KORA Augsburg, Germany, surveys conducted in 1984-1995, being employed at baseline examination and followed up on average for 12.6 years. cenocepacia localizes in bacterium-containing vacuoles that exhibit a pronounced delay in phagolysosomal fusion. While the diagnosis may be suggested on chest radiographs, bronchography in the past has been the definitive diagnostic modality. Since July 1983, 57 patients with surgically inaccessible AOVMs of the brain were treated using helium ion (47 patients) or linear accelerator (10 patients) radiosurgery.

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Perspectives in international neurosurgery: neurosurgery in Indonesia. Plasma beta-endorphin, Met-enkephalin and Peptide F immunoreactivity (ir) were measured at rest and following exercise on three days (days 1, 4, 8) of an eight day heat acclimation regime. The maximum tolerable dose of 1 alpha(OH)D3 varied individually, but was in the range of 2-4 micrograms daily.

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Furthermore, autocorrelations exist between indicator traits and predicted MEm. By fusion of C3H mouse spleen cells, immunized with a PCA extract from liver metastases of a colon tumor, and Sp2/O-Ag14 myeloma cells, we produced several clones secreting monoclonal antibodies (MAb) with reactivity against carcinoembryonic antigen (CEA). The temporal evolution of self-aligned nano-patterns may often evolve with an additional scale-invariance, which leads to breakdown of the well-established dynamic scaling law. In contrast, the enzyme acted on various acyl residues in a series of methyl esters, such as dimethyl succinate, methyl methacrylate, and dimethyl malate. Genetic and neutralization properties of HIV-1 env clones from subtype B/BC/AE infections in China.

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These 21 patients had few clinical or echocardiographic signs of classic tamponade. Flashlamp pumped dye (FPDL), Q-switched Nd:YAG, and alexandrite lasers are the most clinically used laser lithotriptors. Our results are consistent with data from model systems suggesting that both uPA and uPAR are necessary for metastasis.

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Metastatic adrenocortical carcinoma treated by repeated resection: a case report of long-term survival over 18 years. Results of the pilot study confirm that the RFEC is feasible, easy to use in practice, and different from disease-oriented classifications in its system of classifying the reasons for encounter. The degrees of communication competence and self-efficacy of ER nurses were good, with higher scores than the median values.

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Purified D-factor caused dose-dependent inhibition of the development of this concentrative capacity. The linearity of the VLDL increase and the very early response in the Intralipid-treated rats suggest that enhanced synthesis of VLDL is not a major cause for the accumulation. Mg-ATP (25 microM) induced cellular acidification in relation to an increase in the concentration of cytosolic free Ca. Propofol injection pain was higher in the PF group (odds ratio 1.78). The carboxyl function of pepstatin has been coupled, through an amide bond, to methoxypoly(ethylene glycol) (5 kDa), to which an amino function had been previously grafted.

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A single mechanism accounting for the extraordinary prevalence of hypogammaglobulinemia in young patients with cystic fibrosis was not defined in studies of T and B-lymphocyte function in vitro or in studies of IgG metabolism in vivo. Construct validity was supported by significant associates between MSQOL-54 scales and degree of multiple sclerosis symptom severity in the prior year, level of ambulation, employment limitations due to health, admission to hospital in the previous year, and depressive symptoms.

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All these considerations shed light on the thermodynamics of the nanobubbles generated experimentally. Comparisons were made with a group of 103 adults who were similar with regard to race, sex, age, socioeconomic status, dental awareness, and oral hygiene status but had malocclusions that had not been orthodontically treated. The 21K protein is phosphorylated on cell activation with concanavalin A (Con A).

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Photoaffinity labeling of Escherichia coli ribosomes by an aryl azide analogue of puromycin. Oligosaccharides released enzymatically by N-glycanase from fetuin, alpha-acid glycoprotein, human chorionic gonadotropin, platelet-derived growth factor, and kallikrein were chromatographed on a polymeric pellicular anion-exchange column at pH values of 5 and 13. The addition of jaundiced human sera to the culture also causes similar changes. Increasing the osmolarity of the extracellular solution by 40 mosmol/l led to a sustained and reversible depolarization of the membrane potential.

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Posttransplant lymphoproliferative disorder in pediatric bone marrow transplant recipients: disseminated disease of donor origin demonstrated by fluorescence in situ hybridization. Apoptosis in brain and gut tissue of mice fed a seed preparation of the cycad Lepidozamia peroffskyana. Further analysis suggests that NATs constitute a comprehensive transport metabolon for the epithelial uptake and redistribution of essential amino acids including precursors of several neurotransmitters. A luminescent linear trinuclear magnesium complex assembled from a phosphorus-based tris-hydrazone ligand.

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This paper describes the construction of pSG10, the first mycobacterial promoter probe shuttle vector to use the structural gene of a bacterial luciferase as a reporter gene. The trapeziometacarpal (TM) joint is often the site of painful arthrosis, particularly in women at the onset of the fourth decade. This is an investigation of the role that the accident and emergency department of the Auckland Hospital plays in the provision of medical care in the Auckland area.

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These data suggest that EBOV IRADs have profound effects on the host adaptive immune response through massive transcriptional downregulation of DC. The results revealed that all nasal secretion samples from five selected individuals experiencing intensive shedding events contained cell-free OvHV-2 virions. Drug-induced DP does not appear to represent a distinct clinical syndrome.

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We report here results which confirm the hypersensitivity of Bloom syndrome fibroblasts as measured by cell killing but show that they have a normal sensitivity to mitomycin C as measured by sister chromatid exchange induction. One surviving patient underwent a diagnostic lymph node biopsy which revealed tuberculous lymphadenopathy.

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With constant concentration of placental inhibitor the rate of inhibition of the two-chain form was fast in contrast to that of the one-chain form. Fifty four patients with cancer in the lumen of trachea-bronchus proved by histopathology were treated with PDT.

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Three groups were located within the confines of the ipsilateral vestibular nuclear complex (in the lateral, tangential and descending nucleus) and two additional groups, each bilateral, were located in the reticular formation. pteronyssinus was a poor inhibitor of the allergenic components of A. Comparison of two experimental models for combined hepatocyte-islet transplantation. Many factors, such as GP and practice characteristics, influence medical equipment adoption. A number of studies suggest that cancer stem cells are essential for tumour growth, and failure to target these cells can result in tumour relapse.

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Two patients treated topically against dermatophytes with a naftifine containing antifungal became allergic to the efficacious component naftifine. Blood samples were collected for up to 120 hours post dose for pharmacokinetic analysis.

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Here we report a systematic attempt to reconstruct the locomotor behaviour of early hominids by looking at a major component of the mechanism for the unconscious perception of movement, namely by examining the vestibular system of living primates and early hominids. Results indicate that the anticarcinogenic potential of foods containing polyphenols may not be based on the effects of individual compounds, but may involve a synergistic enhancement of the anticancer effects. Hepatic scintigraphy using 99mTc-colloid in liver cirrhosis in children Maximal oxygen uptake during treadmill walking and running at various speeds. A reporting system for the laboratory to communicate quantitative antimicrobic susceptibility test results to the physician in a manner that will optimize proper utilization of such test results is described.

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Virus infectivity was not necessary to stimulate the release of IFN-alpha, beta from CTL, but acid-inactivation of virus abrogated its IFN-inducing property. The interpretation of neurochemical studies of attention deficit disorder (ADD) with hyperactivity is complicated by the variability in diagnosis and by the limitations of single neurochemical measures--whose levels may be compensated by chronic feedback mechanisms. Groups of patients at very high and very low risk of sudden death were identified using conjunction and inclusive disjunction of the foregoing variable.

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Multiple (MS) sclerosis is a chronic inflammatory demyelinating disease of the central nervous system with the pathological hallmarks of inflammation, demyelination, axon loss and gliosis. Zeaxanthin was easily incorporated into liposomes constructed from the fully saturated lipid L-alpha-dimyristoyl-phosphatidylcholine (C14:0) and from egg lecithin, and its absorbance spectrum in liposomes strongly resembles in shape and amplitude that of zeaxanthin dissolved in methanol. Unfortunately, both methods have inherent problems and limitations requiring improvements in the technique.

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Effect of educational program and interview on adoption of guidelines for the management of neonatal hyperbilirubinemia. In conclusion, our findings indicate that submissiveness, known to be an important element of depressive-like behavioral abnormalities, is strongly linked with changes in Syn IIb expression. In this study LGBP was performed in an ante-colic ante-gastric pattern in a double loop manner and the prevalence and distribution of pain in morbidly obese patients undergoing LGBP was assessed. Over 95 per cent of the 46 eyes in this series of 45 patients no longer have epiphora.

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Mutational analysis of colicin 5 and exchange of DNA fragments between the most closely related colicins, colicins 5 and 10, and between their immunity proteins localized the regions that determine the reaction specificity between colicin 5 and its immunity protein to residues 405 to 424 of colicin 5, the region corresponding to the amphiphilic alpha-helix 6 of the similar colicins E1 and Ia. To assess the prevalence of traditional vaginal agent use in Malawian women and its association with HIV infection.