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Expansia (Clopidogrel)

Expansia bisulfate (Expansia) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Expansia prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Expansia is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Expansia bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack, and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Expansia bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Expansia bisulfate was approved by the FDA in 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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A double antibody staining battery was utilized with ultraviolet fluorescent microscopy, and was analysed by an observer blinded to the antibody and lesion type. Association Between rs2200733 Polymorphism on Chromosome 4q25 and Atrial Fibrillation in a Greek Population. In 22 patients with mild hypertension and less LV hypertrophy, however, all DE filling parameters were normal. One patient (Group 1) deteriorated while on counterpulsation, and underwent urgent angiography and operative intervention within 24 hours of balloon insertion.

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In individuals with MCI, hippocampal volume loss appears greater among those with a history of concussion. Using double-label immunofluorescence assays (IFA) in transient expression assays, we have examined the intracellular localization of these three proteins in DNA-transfected cells. The T7 RNA polymerase was supplied by infection with a recombinant vaccinia virus. Twenty-four hours later she developed symptoms of decreased peripheral blood flow in all four limbs. The present research revealed that miR-494 was significantly decreased in PC cell lines and tissues.

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First, potentials from transitional sinus tissue propagated toward the atrium and caused low-voltage waves that preceded and slurred the onset of the atrial initial negativity. To establish whether the presence of mutant or normal CFTR directly influences the O-glycosylation and sulphation of mucins in airway epithelial cells, we used the CFT1-LC3 (DeltaF508 CFTR mutant) and CFT1-LCFSN (wild-type CFTR corrected) human airway epithelial cell lines. However, stabilization of content uniformity, a twofold reduction of potency loss in an open-dish stability test, and chemical stability are possible with at least three of the additives studied. Free glycogen in vaginal fluids is associated with Lactobacillus colonization and low vaginal pH. Pieces of mouse seminal vesicles were incubated in vitro for 0.5, 1, 2, 4, 6, or 8 h and the autophagic vacuoles formed in the epithelial cells during incubation were counted.

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Vapours of each test product plus those from a synthetic blend of the pheromone were delivered to the walking tick in an air stream on a locomotion compensator. Fire and death: the pyrin domain joins the death-domain superfamily.

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Through a collaboration between facilities, persons with disabilities and accessibility consultants, the approach provides a process of incremental change through readily achievable barrier removal and by providing an information and educational resource concerning barrier removal, disability awareness, and economic and information resources. In an attempt to correct anterolateral rotatory instability of the knee, 30 consecutive patients underwent a surgical procedure similar to that described by Ellison (Ellison AE: A modified procedure for the extra-articular replacement of the anterior cruciate ligament. Cryoelectron microscopy shows these structures to be composed of tethered, rather than adhering, vesicles in their original, unstressed state.

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Novel biomarkers are of particular interest for predicting cancer prognosis. In addition, transfection of DLD-1 and HT-29 cells with siRNA against ATG genes reduced EGCG synergistic effect. We evaluated treatment outcome and quality of life among 23 breast cancer patients treated with conservative surgery and radiation among the 1624 patients treated at the Joint Center for Radiation Therapy between 1968 and 1985 who had subsequent pregnancies as compared with 23 patients without subsequent pregnancy matched by age and stage at diagnosis and time to pregnancy without recurrence. Emergency endoscopy in the diagnosis and treatment of acute surgical diseases of the gastrointestinal tract

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An analytic sample of 5,485 women, including 99 breast cancer cases (34 premenopausal and 65 postmenopausal at NHANES I baseline), was examined for associations with dietary intake of fat, percent energy from fat, total energy, saturated fat, polyunsaturated fat, monounsaturated fat, and cholesterol on the basis of a 24-hour recall administered at the baseline NHANES I examination. To describe the histopathological features encountered in a series of patients with Proteus syndrome from a single centre.

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A concentration detection limit of 8.10(-9) mol/L for the 20-mer phosphorothioate ISIS5132, isolated from rat serum, was found. It is based on an exchange of films by mail, with provision for ongoing feedback of results. Multivariable regression modelling was used to identify independent predictors of axillary artery injury and to assess its relationship with inpatient outcomes. Clones resistant to 30 mug/ml ethionine were isolated after mutagenesis at an induced mutation frequency of 2.3 X 10(-5).

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Role of eosinophilic granulocytes in women with infertility and pelvic adhesions. Expression of variants in clinical samples was analyzed by semi-quantitative RT-PCR.

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This observation leads to the conclusion that most fibrils of the space of Disse contain type III in addition to type I collagen molecules. Hybridizing fragments were of differing sizes, indicating that evolutionary divergence among group I members has occurred. We also found that melanopsin could activate the cation channel TRPC3, a mammalian homolog of the Drosophila phototransduction channels TRP and TRPL. Screening trials of several candidate formulations have been undertaken: buffered sodium metabisulphite, releasing sulphur dioxide as a vapour-phase bactericide, has now been introduced as an effective bin exchnage system. It is unclear, however, whether this apparent increase in prevalence is accompanied by an increase in severity of the disorder.

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Clinical records included age, serum PSA, sextant prostate needle biopsy, previous medical therapy, surgical procedure and histological findings. We implemented a software tool called GENESIS for three different genome rearrangement problems: Sorting a unichromosomal genome by weighted reversals and transpositions (SwRT), sorting a multichromosomal genome by reversals, translocations, fusions and fissions (SRTl), and sorting a multichromosomal genome by weighted reversals, translocations, fusions, fissions and transpositions (SwRTTl). In ten patients with idiopathic segmental dystonia we prospectively evaluated the effect of pallidal stimulation on quality of life using the SF-36 questionnaire. The focal length is assumed to increase monotonically toward the edge of the collimator. In transient transfection assays, expression of COL1A2-CAT, a chimeric gene bearing 3500 bp upstream the bone/tendon transcription start site from the human alpha 2(I) gene fused to the CAT gene, is stimulated severalfold in RA-treated chondrocytes.

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Ureaplasma species was identified from synovial fluid on 2 separate occasions using a broad-range 16S ribosomal RNA gene polymerase chain reaction. Evacuation of protein and starch solutions from the stomach is determined by the effect of products of their hydrolysis in the small intestine and duodenum. The distribution of actin in the adherens junction belt was asymmetric. These could be considered as parts of a retarded transition of C-section neonates in the early adaptation, but some of the differences in global EEG pattern could not be explained in this way.

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The primary focus of this study was to assess biofilm adhesion to orthopaedic metals in their first 48 h in a femoral intramedullary implantation model. A rigid contact scope is a recent development of optical instrument which allows observations of the superficial layers of the mucosai epithelium in gynecology and otorhinolaryngology. A similar result was obtained using granddaughter cells present after 24 hours of incubation.

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The rise in the mitotic index of Yoshida ascites tumor cells is consistent with the results of previous work showing significantly increased cell proliferation in the normal tissues of animals lesioned in the tuberoinfundibular region. However, as one modification, removal of the insular cortex can easily be performed, if necessary, and, as a second modification, the entire transventricular deafferentation can be performed through a sylvian key hole. To investigate whether prostate-specific antigen (PSA) fluctuation correlates with a prostate cancer and to assess whether PSA fluctuation could be used for diagnosis of prostate cancer.

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Serum samples in patients were tested by indirect immunofluorescence (IIF) slide kit (INOVA) for c-ANCA and p-ANCA and by ELISA for myeloperoxidase (MPO-ANCA) and proteinase 3 (PR3-ANCA). Long-term DOCA administration markedly increased HCO3-ATPase activity in the distal convoluted and collecting tubule.

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Our results illustrated that miR-29b as a suppressor has a critical role in CRC progression, which suggests its potential role in the molecular therapy of patients with advanced CRC. Several threshold parameters are obtained that determine persistence of endemic proportions, persistence of total population, and the persistence of infective population given the extinction of endemic proportions in a population tending to infinity. A simplified approach to stem cell mobilization in multiple myeloma patients not previously treated with alkylating agents. Keratin gene expression in another Pam line, 321, differs from that of Pam 212 cells in that decreased expression of these three keratin genes occurs.

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Computed tomography scanning has provided important evidence of lung hyperinflation even after the use of low tidal volume in a specific category of patients. Calcium signalling during the cleavage period of zebrafish development. Extensive destruction of a vertebral body with little involvement of the adjacent vertebrae, lower lumbar spondylolysis and spondylolisthesis, and discitis with calcification were striking radiological findings hitherto undescribed in brucellosis. Thermography can also function as a useful, noninvasive screening technique to aid in selecting patients for spermatic venography and embolization therapy.

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On clinical usefulness of Tl-201 scintigraphy for the management of malignant soft tissue tumors. Pre- and postoperative myocardial and blood pool scans in a case of left ventricular aneurysm: Case report.

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Tumour growth can easily be monitored by cystoscopy, but cannot be used to distinguish NMIBC from muscle-invasive bladder cancer. On the uniqueness of the receding contact angle: effects of substrate roughness and humidity on evaporation of water drops. We will review the results of recent clinical trials conducted in FXS that were based on some of the preclinical findings, and discuss how the observed outcomes and obstacles will inform future therapy development in FXS and other autism spectrum disorders. Because the method is not restricted to the reconstruction from only C(alpha) coordinates, reconstruction based on C(beta) coordinates is also demonstrated.

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The diagnosis and management decisions regarding uncomplicated lesions, such as atrial septal defect, ventricular septal defect, patent ductus arteriosus, and tetralogy of Fallot, can be accomplished by echocardiography alone. In addition, food supplementation with extracts of Serenoa repens and a combination of the antioxidants selenium, (cis)-lycopene and natural vitamin E, together with fish oil rich in long-chain polyunsaturated essential fatty acids of the omega-3 group seems warranted.

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MPtV-VLPs were shown by FACS analysis to bind to different cells, independent of MHC class I antigen expression. Size and detergent binding of adenylate cyclase from bovine cerebral cortex. Shifts in the relative frequencies of leukemia types may have been affected by changes in classification criteria, changes in the use of histologic terms over time, and the expanded use of immunophenotyping and other technology to characterize acute leukemias. We present an MRI examination of an extra-axial hematoma of the clivus in a child with head trauma, not visible on C.

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The management of primary hypothyroidism with levothyroxine (L-T4) is simple, effective and safe, and most patients report improved well-being on initiation of treatment. During the subsequent 24 hours, the levels fell to 4 to 15 times and 4 to 11 times the normal values. Visually guided saccades were examined in 44 antipsychotic-naive patients experiencing their first episode of schizophrenia prior to treatment and again after 6, 26, and 52 weeks of antipsychotic treatment. An infant born of a diabetic mother at 36 weeks developed three liver abscesses consecutive to umbilical vein catheterization. An unusual congenital cataract: the spirochete-like cataract with cerulean opacities.

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Our results suggest that implant anchorage is useful for correction of skeletal Class III severe anterior openbite cases. A mutation in the Arabidopsis thaliana LCB1 gene, lcb1-1, was found to cause embryo lethality. Industry constraints have created an environment where caring for the patient and employee has become easily discarded in favor of the rigors of technological care. The first oral immunotherapy double-blinded trial for Artemisia pollen asthma research was conducted in China in 1989 and published in 1990. Radioprotection of pyrimidines by oxygen and sensitization by phosphate: a feature of their electron adducts.

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Cicuitry analysis of the outer plexiform layer in the rabbit retina. Mental health workers may, therefore, not consider, and consequently miss, this important diagnosis. A common cause of dementia in late midlife and old age is Alzheimer disease (AD), which affects more than one in 20 individuals over the age of 65.

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Indication for CT scans of the TMJ and their evaluation in dysfunctions of the masticatory apparatus In both years for which data were available, there were indications that males with relatively brighter UV coloration, and that paired with females that produced male-biased clutches, were more likely to survive to the next year. Poly(dimethyldiallylammonium chloride) spin-coated on a screen-printed electrochemical cell provides sufficient ionic conductivity for the cell to function as a gas sensor for oxygen, which is detected by reduction at a platinum working electrode. When yeast strains were cultivated on maltose, the synthesis of trehalose already started in the exponential phase of growth, well before exhaustion of the sugar from the medium. The correction of lysosomal enzyme deficiency was investigated for various organs of beta-glucuronidase-deficient C3H/Rij mice after allogeneic bone marrow transplantation from an enzymatically normal donor strain (C57BL/Rij).

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A single H2O2 treatment of 3.1 mg/L or more for 1 h effectively eliminated external bacteria, concentrations of 6.5 mg/L or more appeared to effectively kill Ichthyobodo spp., and none of the treatments tested was effective against Trichodina spp. Auxotrophic Rhizobium meliloti strain RM 246 carries two independent mutations: in the biosynthesis of cysteine (cys) and symbiotic nitrogen fixation process (fix). However, some still malfunction, some do not deliver adequate O2 concentrations for hospital use, and there is still a great variability in their performance.

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In case of a locally advanced rectal GIST, an extended or multivisceral resection with significant morbidity and -mortality is often necessary. Digital subtraction angiography (DSA) is the reference diagnostic imaging modality for MMD. All three patients developed bilateral conjunctival hyperemia and fine corneal epithelial opacities and refractile microcysts that were more numerous in the central than in the peripheral cornea. Microarray analysis indicates that the removal of PIAS1 results in an increased expression of a subset of NF-kappaB-mediated genes in response to tumor necrosis factor alpha and lipopolysaccharide. Whether standardization of house dust extract is at all feasible, and if so, worthwhile, remains to be seen.

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Within the first 3 years after diagnosis of Gleason score 6 prostate cancer, there is a relatively low risk of grade progression. The inhibitory effect of alpha1-antitrypsin on kallikrein activity should be taken into account in studies in which kallikrein activity is estimated. Accumulation and Distribution of Lead and Chromium in Laboratory-Scale Constructed Wetlands Inoculated with Metal-Tolerant Bacteria. Haptoglobin-related protein (Hpr) is a component of a minor subspecies of high density lipoproteins (HDL) that function in innate immunity. Role of plant polyphenols in acrylamide formation and elimination.

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Automated classification system (ACS) for detection of high risk groups exposed to radiation Thyroid abnormalities seem to be common not only in patients with T1DM but also in their FDR, which suggests that screening strategies for thyroid diseases might also be useful to these individuals.

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The inhibitory effect of methionine-enkephalin on pancreatic response to endogenous stimulants was more pronounced than that to exogenous hormones and was accompanied by a significant reduction in plasma immuno-reactive secretin concentration. It is concluded that in suitably selected cases, resection can be performed with a mortality considered acceptable for palliative intubation whilst conferring greater survival and restoration of normal swallowing. The results indicated that HHV-6 DNA was present in uncultured peripheral blood mononuclear cells (PBMC) and that a 1.3-kb viral transcript was expressed in both cases.

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Here, we aim to resolve this issue by determining the rates of cell proliferation and death during the chronic stage of the bovine leukemia virus (BLV) infection, called bovine persistent lymphocytosis (PL). Northern blot hybridization studies revealed that EC-GI cells metronidazole purchase uk downton produced exclusively mRNA for IL-1 alpha. A simple size-exclusion high-performance liquid chromatography (HPLC) method for separation of collagen monomers and oligomers using a Bio-Gel TSK 60XL column has been developed for type I collagen from calf skin. Because IGF-I and IGFBP-3 stabilize each other, SRC-3(-/-) mice were crossbred with the liver-specific transthyretin (TTR)-IGF-I transgenic mice to assess the relationship between reduced IGF-I and IGFBP-3. A molecular explanation of frequency-dependent selection in Drosophila.

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From the results of this study, we suggest that proximal invasion of extrahepatic bile duct cancer can be diagnosed using IDUS. The major constituent is an acidic polysaccharide composed of L-rhamnose: D-galactose: D-galacturonic acid: cyclophosphamide weekly dosing D-glucuronic acid in the molar ratio of 5:8:3:2.

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Can ventilation-feedback training augment exercise tolerance in patients with chronic obstructive pulmonary disease? At postoperative seven months, she underwent bidirectional cavopulmonary shunt uneventfully, and she has been followed-up for two months in a stable state without any problem in the pulmonary venous pathway. Tunable dielectric properties of ferrite-dielectric loric-100 allopurinol tablets based metamaterial. Low serum thyrotropin (thyroid-stimulating hormone) in older persons without hyperthyroidism.

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Agreement between the spatio-temporal gait parameters from treadmill-based photoelectric cell and the instrumented treadmill system in healthy young adults and stroke patients. It could be explained by a modification of the accessibility of Concanavalin A receptors. To investigate the correlation between signal intensity of the posterior pituitary gland on magnetic resonance (MR) images and levels of plasma antidiuretic hormone (ADH) in patients undergoing hemodialysis. A very large open reading frame composed of 6,096 bases, which encodes 2,032 amino acid residues with an M(r) rabeprazole sodium and itopride hydrochloride of 224,992, was found.

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Eckerskorn: Clinical aspects and experimental findings in so-called senile cataract (Nematoda: Cystidicolidae) from freshwater fishes with a key sildalis uk top to the members of the genus in the region.

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