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Supplementing metabolizable protein to ewes during late gestation: II. Our study demonstrates that BM is a powerful antioxidant which prevents cognitive impairment, oxidative damage, and morphological changes in the ICV-STZ-infused rats. The second mode uses long-acting GnRH agonists administered in a depot delivery to produce a paradoxical desensitization of pituitary gonadotropin secretion which, in turn, results in a complete ablation of the reproductive axis. TFES prevents myocardial ischemia/reperfusion injury, and this cardioprotective effect is probably via inhibiting mitochondrial permeability transition pore opening.

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Although mutant JS94 did not produce active lipoamide dehydrogenase, cell-free extracts of this mutant contained a protein which cross-reacted with anti-LPD-val. Patient is classified as stage III according to Durie and Salmon criteria in view of anemia and multiple lytic lesions observed. Tele group received telerehabilitation but the Conv group received conventional therapy with two persons in each group for three sessions per week and for four weeks. This subcellular localization, in full agreement with biochemical results appears visualized for the first time in E.M. The literature contains reports of major skin contractures, hypothyroidism, laryngeal and tracheal stenosis, major vessel stenosis, and hypoplastic development of cervical vertebrae, but very rarely are all these complications seen in a single patient.

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These studies show that on continuous exposure, the non-polyglutamylatable inhibitors DHFR (3-5) can exhibit superior antifolate activity compared to the polyglutamylatable methotrexate, presumably due to their enhanced transport to these cell lines. Synthesis and anticancer activity studies of cyclopamine derivatives. To further elucidate the function of RRAG A/Gtr1p, we isolated a protein that interacts with RRAG A. The control of dental caries by manipulating dentinal fluid movement. This article discusses counselling in general practice in relation to a series of cases where a presentation of nightmares disguised underlying repressed traumas.

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Vaginal epithelial abnormalities in patients with CIN: clinical and pathological features and management. This finding suggests that l-Asc stimulates the differentiation of smooth muscle cells.

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Otherwise, clinically there was no difference between the three groups except for more frequent liver disease within the second degree of kinship in the HBsAg patients. Positional popliteal artery obstruction is believed to be an important factor contributing to popliteal artery entrapment syndromes.

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We present a method in which noncontinuously binding (loop-out) primers are used to exclude regions of DNA that typically interfere with PCR amplification and/or analysis by Sanger sequencing. The effects of endocrine manipulations on portal blood catecholamine concentrations. The outcome measures used were cervical spine range of movement, neck strength, and neck muscle fatigability. There are no pathognomonic laboratory criteria for the diagnosis of ILD in children other than the characteristic findings on histologic examination of the lung. The structure function relationship in the human insulin receptor

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A consistent finding was that, for never married persons, rates of use for both short-stay hospitals and nursing homes, as measured by discharge rates, increased to a greater degree with age than they did for the other marital groups. However, more studies are necessary to assess the effects of leucine supplementation in already-obese subjects. Ultrasound and CT scans have been used to examine 12 patients with suspected medial orbital wall fractures.

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C57BL/6 mice sensitized by abdominal, dermal exposure to irradiated (50 kR) Schistosoma mansoni cercariae develop partial protection against subsequent exposure with unattenuated cercariae and express cell-mediated cutaneous sensitivity upon challenge with irradiated cercariae. Chloroplast chlB gene is required for light-independent chlorophyll accumulation in Chlamydomonas reinhardtii. Taxol, a plant-derived antimitotic, was recently found to mimic several of the effects of endotoxic bacterial lipopolysaccharide on murine macrophages. Amphotropic but not atherotropic: another caveat for adenoviral gene therapy.

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AKF-PD treatment inhibits the progression of renal interstitial fibrosis by suppressing oxidative stress and ERK/MAPK signaling pathway. The current study investigated whether intranasal administration of oxytocin leads to increased self-other integration using a social Simon task.

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Protein and enzyme polymorphisms in affective disorders in Northern Greece. Viability of Schistosoma mansoni miracidia, obtained from feces and hepatic granulomas of mice experimentally infected with the BH strain These results highlight the importance of accurate fracture reduction in facilitating implant placement as well as the importance of good surgical technique rather than reliance purely upon the implant.

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The auditory evoked brainstem electric response (ABR) in cochlear hearing loss. The Src homology 2 sequence of FER is required for directly binding cortactin, and phosphorylation of the FER-cortactin complex is up-regulated in cells treated with peptide growth factors. We have constructed a recombinant gene library using the cloned coat protein gene of Escherichia coli RNA bacteriophage fr as a carrier. Hormonal effect of subcapsular orchiectomy versus total orchiectomy. No clinically significant DVT was found using either enoxaparin or warfarin prophylaxis after TKA in Southern Iran.

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Rapid protection of the gastroduodenal mucosa against aspirin-induced damage by rabeprazole. However, its contribution to the amount and distribution of body fat is under investigation.

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The prolongation of survival time of P388 leukemia-bearing mice by DFMO (1,500 mg/kg) was 1.12-fold, while that by DFMO (1,500 mg/kg) plus APCHA (25 mg/kg) was 1.30-fold. A disgenic testis on the left side and a primordial ovary on the right one was showed by laparotomy performed in this subject in the prepubertal age.

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Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells. Removal of this insertion by markerless mutagenesis restored the highly endotheliotropic phenotype, indicating that the loss of endothelial cell tropism was caused by this insertion.

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The development of manual midline crossing in 2- to 6-year-old children. While on the ground, the ventral giant interneurons (ventrals) encode the wind direction and specify turn direction, whereas while flying the dorsal giant interneurons (dorsals) appear to do so.

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alpha-Ketoglutarate, ferrous iron, and molecular oxygen were required for the enzyme activity. Over a time period of 15 years, we have identified six patients with one or more solid renal tumours in our population of approximately 50 patients with chronic Li nephropathy. Inhibition of TxB2 synthesis was accompanied by increased generation of PGE2, PGF2 alpha, and PGD2, as shown by radioimmunoassay, thin-layer radiochromatography, and high-resolution gas chromatography-mass spectrometry.

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A composite multilocus haplotype based on hybridization to six anonymous probes could differentiate each of the nine isolates tested, suggesting that these probes may be useful for further studies of the population biology and epidemiology of this pathogen. Sporadic mutations affecting almost each major player of the Wnt/beta1-catenin pathway have been described in a variety of human carcinomas. This patient illustrates that PH-1 may present in adulthood, and, in the setting of cutaneous necrosis associated with end-stage renal disease, it may be confused with calciphylaxis. Measuring linear and quadratic contributions to neuronal response.

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Acquired immune deficiency syndrome (AIDS) manifesting as anogenital herpes zoster eruption: demonstration of virus-like particles in lymphocytes. On the other side, dose-dependent plasma dispositions of ABZ-SO were observed following SC administration at increased doses (10 and 15 mg/kg) in goats.

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The olivocerebellar projection in the rat: an autoradiographic study. The same shift is in fact observed with extracts prepared from a differentiated rat thyroid cell line which synthesizes and secretes thyroglobulin, while no similar shift is detected when cell unable to express their endogenous thyroglobulin gene or tissues different from thyroid are used as a source of nuclear extract. In recent years, advances in recombinant DNA technology allowed the production of recombinant therapeutic proteins, among which glycosylated proteins displayed differences compared to their native counterparts, including antigenic carbohydrates.

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Curcumin induces ER stress-mediated apoptosis through selective generation of reactive oxygen species in cervical cancer cells. DNA-binding properties of a lac repressor mutant incapable of forming tetramers. Intraosseous blood pressure in occlusive arterial diseases of the extremities Changes in the sleep pattern were investigated in rats given actinomycin S3 (AcS3, 0.25 mg/kg, intraventricularly), an inhibitor of RNA synthesis, at 0000, 0600, 1200, and 1800.

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However, IL-4 has been reported to mediate functional effects in several solid tumor cell lines. A distinctive type of neutrophilic dermatosis associated with myelogenous leukemia and chemotherapy. Possibilities of computed tomography as exemplified by the human temporomandibular joint

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Thus, if glucocorticoids play any role in the progressive muscle atrophy seen in aging, this is unlikely to result from an activation of the ubiquitin-proteasome proteolytic pathway. Mortality in acute upper gastrointestinal haemorrhage: a six-year survey from the University Hospital of Wales. These results were supported by the changes in the concentration of a complement component (C1) and in the IgG subclasses in the immune complex-enriched fraction prepared by polyethylene glycol precipitation from different serum samples of individual patients with leukaemia.

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To define the sites in the extracellular domain of the human thyrotropin (TSH) receptor that are involved in TSH binding and signal transduction we constructed chimeric thyrotropin-luteinizing hormone/chorionic gonadotropin (TSH-LH/CG) receptors. The complication rate in patients free of recurrence was 1.9 per cent and in those with recurrence 23 per cent, which indicates that severe complications are often caused by recurrence of the tumour. HLA-A, B, C and beta 2m levels are known to vary among tissues and cell lines.

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Mirabella and colleagues compared conventional controlled ventilation with a mode that combines several potentially lung-protective properties - non-invasively applied neurally adjusted ventilatory assist - in an animal experiment. The complex biomechanical events associated with embryo development are investigated in vivo, by using femtosecond laser pulse-induced ablation combined with multimodal nonlinear microscopy. To improve a drug delivery in BNCT, we devised transferrin-conjugated polyethylene-glycol liposome encapsulating sodium borocaptate (TF-PEG-BSH). The main photocatalytic intermediates detected during the degradation of NIs were identified. In contrast, ADM gene expression in renal and hepatic tissues was not significantly altered following the onset of sepsis.

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In this report, we show cBCGF-60kD can be radioiodinated with no significant loss of biologic activity and bound specifically to B cell surface membrane receptors. The interruption of collateral blood flow to the ischemic canine myocardium by embolization of a coronary artery with latex: effects on conduction delay and ventricular arrhythmias.

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Untreated rabbits were compared with those infused with quercetin (5 mg/kg for 2 min) during hindlimb ischaemia (2.5 h) and reperfusion (2 h). Immunofluorescence staining was used to localize endogenous and chimeric G alpha i proteins in LLC-PK1 cells.

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Catecholamine determination in sequential urine voiding: a method for detecting pheochromocytoma in patients without elevated urinary catecholamines. Ergonomic intervention in the form of new tools with lower vibration levels and the use of International Standards Organizaiton (ISO) 10819 antivibration gloves were associated with a decrease in the pathologic findings and symptoms in these workers. Epigenetic regulation by histone methylation and histone variants. The peripheral blood and bone marrow showed differentiated and apparently undifferentiated blasts.

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Treatment of cognitive impairment in multiple sclerosis: is the use of acetylcholinesterase inhibitors a viable option? Relationship of gender and menstrual status to symptoms and medication side effects in patients with schizophrenia. The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. 1,25-Dihydroxyvitamin D3 receptor in a cultured human breast cancer cell line (MCF 7 cells). Expression of wild-type and mutant subunits of the cAMP-dependent protein kinase.

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Major histocompatibility complex class I molecules and resistance against intracellular pathogens. The severity of dysmenorrhoea has close correlation with posterior cul-de-sac obliteration. Treatment of marked anteroposterior and transverse discrepancies in mandibular prognathism. No correlation was found in FM patients between the total FIQ score and the distance walked in the 6MWT. Analysis of effector cell morphology and effects of interferon on natural killer cell function in the athymic (nude) rat.

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Comparative activity of three analgesics in healthy mice and those made diabetic with alloxan It appears that previously applied methods have underestimated the prevalence. Photoplethysmography (PPG) is a noninvasive optical method accepted in the clinical use for measurements of arterial oxygen saturation. Effects of bicarbonated-alkaline water (Uliveto) on gastric and gallbladder emptying in normal subjects. Further, macrophyte abilities to mitigate different insecticide exposure scenarios (i.e.

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Food deprivation consisted of removal of all food every other day. Comparison of cardiac function in male and female diabetic rats.

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Although this data implies complement activation occurs in inflamed joints in juvenile arthritis, the specific role of immune complexes remains unproven. Sequencing of the mtDNA cytochrome b gene and reconstruction of the matriarchal relationships between wood and field mice of the genus Apodemus (Muridae, Rodentia) The evolution of this new pattern, and of dominant reduced responsiveness in general, is discussed and its relevance to immunological diseases assessed. Hemorrhagic complication to portal hypertension--an assessment of therapeutic alternatives Marked enlargement of the left lobe of the liver causing a false-positive spleen image.

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Magnetic resonance angiography and duplex imaging: noninvasive tests for selecting symptomatic carotid endarterectomy candidates. Local ablation therapy combined with liver resection for multiple hepatocellular carcinomas In this paper we share our experience of one such rare case and review the literature about this condition. Nonablation applications of laser energy may also have a role in the treatment of atherosclerosis.

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The patient developed substernal chest pain during a scheduled 40-g (400-mg/kg) infusion. Effect of environmental factors on lectin biosynthesis by Bacillus mesentericus

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Increased metal ion concentrations would facilitate these oxidative processes. If the patient does not desire future pregnancy, she should be sterilized to avoid the risk of repeat ectopic pregnancy. A strinking feature was a prolonged increase in tumour T-cell content. These cells showed a decrease in the relative volume of phagosomes, although organelles concerned with synthesis (the rough endoplasmic reticulum and Golgi zones) were not affected.

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Ultrastructural findings confirm the duality of the cell population. Cerebrospinal fluid phospholipids and cerebrosides in several demyelinating diseases Clenbuterol and terbutaline significantly improved baseline FEV1 and the bronchodilator effects of single oral doses were similar. Tumors in estrogen users were of a significantly lower grade than those of nonusers of the same age.