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Electrical and optical properties of poly(3,4-ethylenedioxythiophene) oxidized with poly(4-styrenesulfonate) and AuCl3-doped reduced graphene oxide/single-walled carbon nanotube films for ultraviolet light-emitting diodes. The high rate of induced breakage shown by phenotypically normal subjects may mean that these individuals have a potential sensitivity to mutagen exposure. Mixed connective tissue disease (MCTS) and systemic lupus erythematosus (LES) Consultation with an otolaryngologist is esential in both diagnosis and management. Specific chemical mediator release such as histamine and the prostaglandins (PG2a or PGD2) associated with headaches has been found in a few patients who were repeatedly challenged with specific foods, using DBPCFC techniques.

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A reversed-phase liquid chromatographic method with amperometric detection has been developed for the simultaneous determination of the noradrenaline metabolite, vanilmandelic acid, the dopamine metabolite, homovanillic acid, and the serotonin metabolite, 5-hydroxyindole acetic acid, in human urine. Increasing sequence length favors alpha-helix over 3(10)-helix in alanine-based peptides: evidence for a length-dependent structural transition. YopD of Yersinia pseudotuberculosis is translocated into the cytosol of HeLa epithelial cells: evidence of a structural domain necessary for translocation. The clinical spectrum of olivopontocerebellar atrophy (OPCA) usually consists of pancerebellar signs with pyramidal and abnormal eye movements.

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Novel Ala94Thr mutation of keratin 14 in epidermolysis bullosa simplex. Concentrations of the potent, HIV(human immunodeficiency virus) inactivating protein, cyanovirin-N (CV-N), which completely inhibit HIV-1 infectivity, do not block the binding of soluble CD4-receptor (sCD4) to HIV-1 lysates nor the attachment of intact HIV-1 virions to several target T-cell lines. Both the spontaneous pulsation rate and intracellular cAMP level were followed.

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The basic program consists of a) information distributed to groups on diets, including a restricted use of carbohydrates, b) instructions in dental hygiene, c) regular use of fluoride in the form of mouth-wash or tooth-brushing with a fluoride-solution. To demonstrate the properties of the method it is applied to synthetic and natural voices, among them six pathological voices, which are characterized by roughness, vocal fry, gratings/scrape, hypofunctional breathiness and voice breaks, or combinations of these.

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The deoxynucleotide fragment d(GpGpCpCpGpGpCpC) was synthesized and crystallized, and its three-dimensional structure was determined by x-ray diffraction techniques to a resolution of 2.25 A. Issuing from the clinical picture in each case the aim of therapy and the application of physiotherapy are described. A significantly and markedly increased incidence of fetuses with malformations, such as exencephaly, cleft jaw, cleft lip, ankyloglossia, club foot, deformity of the vertebral column in the cervical and thoracic regions and of the ribs and ano- or microphthalmia, was observed in both groups treated with DBT. However, the prognosis of metastatic invasive IPMN is as poor as that of ductal adenocarcinoma.

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Total lymphocyte count may provide a simple and cost-effective alternative for prioritizing therapy initiation in resource-limited settings. Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen.

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Serial determinations of blood pressure, blood volume, cardiac output, exchangeable sodium and plasma renin activity were performed. This cross-sectional study investigated self-esteem in relation to age, gender, ethnicity, and risk behaviors among a sample of nonmainstream students. Risk factors for chlorotrichosis include light-colored hair, copper plumbing, long periods when the water was not thoroughly flushed out of the copper pipes, and frequent shampooing. Antibodies against phospholipids appeared spontaneously during the course of experimental Trypanosoma rhodesiense infections in rabbits.

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Ameloblastic fibrosarcoma: an ultrastructural study of the mesenchymal component. Ipilimumab and nivolumab, but not pembrolizumab, have an overall survival (OS) advantage over chemotherapy first line in unresectable/metastatic melanoma.

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Average compressive forces on the spine were estimated for observed combinations of body postures and manual handling and then weighted by frequencies of observed time for the combination. There is evidence that a bilayer artificial skin, used in conjunction with compression bandaging, increases the chance of healing a venous ulcer compared with compression and a simple dressing. alpha-Ketoglutarate versus ketoacids as dietetic substitutes in chronic renal insufficiency. Both of the functional groups introduced onto the polyethylene surface were found to be utilizable for covalent immobilization of protein using carbodiimide for the carboxylic group or mediators such as glutaraldehyde and ethylene glycol diglycidyl ether for the amino group. The effect of low-dose radiation (1-100 cGy) on the growth of lymphoma Raji cells in vitro was examined.

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Pharmacological assessment of the anaesthetic potency and acute toxicity of althesin and its steroidal components in laboratory animals. Enhancement of translational efficiency by the Escherichia coli atpE translational initiation region: its fusion with two human genes. In order to achieve this effect the agglutinin and IgA had to be mixed prior to the addition of anti-IgA. The radiobiology and physics behind the use of radiosurgery are presented, followed by a discussion of promising retrospective and prospective clinical data that has been reported from Japan, Europe, and the United States.

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In the high altitude subtropical region, access to shade minimizes negative heat stress effects on behavior and physiological aspects of dairy cows. Our method highlighted regulatory interactions previously identified in the cell line and a novel finding that the HER2 oncogene, as opposed to the proto-oncogene, upregulates expression of the E2F2 transcription factor.

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By examining physicochemical properties of these forms by various methods including X-ray powder diffractometry and differential scanning calorimetry, it became apparent that PF1022A had one amorphous (form alpha) and three crystalline polymorphic forms, form I, form II and form III. Proteins were focused and separated in first dimension CIEF based on their differences in isoelectric points (pIs).

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Phase II double-blind placebo-controlled randomized study of armodafinil for brain radiation-induced fatigue. Murine splenocytes release an inhibitory peptide of lymphocyte DNA synthesis into serum-free culture medium.

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The transition of forming enamel to maturing enamel was accompanied by a decrease in protein concentration, a distinct change in amino-acid composition, and a rise in the concentration of calcium and phosphate. Salmeterol is an effective long acting inhaled bronchodilator for patients with nocturnal asthma and at a dose of 50 micrograms twice daily improves objective sleep quality. Regulation of skeletal muscle 6-phosphofructo-1-kinase during aging and development. The present study investigated the hypothesis that this medial septal pathway originates in the subfornical organ.

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This information has provided a rational basis for treatment of the disease, which is very effective. Partial amino acid sequences revealed three regions of sequence variation, each variant involving a single amino acid substitution. Low-loss and fabrication tolerant silicon mode-order converters based on novel compact tapers. A successful attempt using the onlay fundic patch method for treatment of spontaneous rupture of the esophagus (SRE) was reported.

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Two patients presented with a history of thalassemia, and one had a history of anemia of undetermined etiology. These results support the idea that Cdk5 activity is involved in altered gene expression after chronic exposure to cocaine and hence impacts the long-lasting changes in neuronal function underlying cocaine addiction.

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In the presence of multiple aneurysms CAT helps to identify the one that caused the hemorrhage. Interference on the haemostasis in dogs with induced coagulopathies by drugs affecting the platelet function.

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Clear indications include situations in need of contrast media when iodinated contrast cannot be administered or to facilitate assessments in pregnant patients and children when exposure to ionizing radiation is considered unacceptable. Dramatic progress has been made recently in determining the genetic and molecular composition of cells. However, selective absorption studies using whole sera and a series of overlapping recombinant peptides of PDC-E2 have suggested that the epitope may also include a large conformational component. However, the response of serum cholesterol level to oral cholesterol ingestion in the former was larger than that in the latter. Serum and organ griseofulvin levels in guinea pigs and serum levels in patients who received a prolonged oral administration of griseofulvin were determined gas-chromatographically.

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Studies of the interaction of leukemic cells and marrow stroma in vitro may provide important information concerning the regulation of leukemic cell behavior. The past 2 decades have seen the development of numerous nerve transfer techniques, by which a denervated peripheral target is reinnervated by a healthy donor nerve. This study has successfully developed the PEAR scale and established its psychometrics based on the compatible scales available. The preodontoblasts do not differentiate in the pulps cultures alone or in association of pulps with no specific epithelium. Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxo-L-norleucine or 2-deoxy-D-glucose.

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The secretion and synthesis of ERP was studied in human alveolar macrophages and in the macrophage-like cell lines THP-1, HL-60, and U937. A quantitative model of myosin phosphorylation and the photomechanical response of the isolated sphincter pupillae of the frog iris. The differing role of HTT function during early development and in adult brain plasticity in causing or reversing depression remains an unexplained paradox. In conclusion, prolonged subcutaneous administration of rh IL-6 on an outpatient basis is safe and feasible.

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Protein content of the evening meal and nocturnal plasma glucose regulation in type-I diabetic subjects. Furthermore, it was shown that in order to achieve the best possible results in a clinical trial, the variable of gingivitis should be used in preference to plaque scores, that only individuals of high and/or moderate susceptibility to inflammation should be selected for inclusion in the statistical analysis, and that sites which have positive signs of disease only, should be included in the statistical analysis. The average length of stay in the hospital was 2 days (range 1-3 days). We describe the clinical impact related to the Stroke Echoscan protocol in our Center. Tachycardia-induced cardiomyopathy is a rare, but reversible form of dilated cardiomyopathy.

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It provides an opportunity to study the pathology of the stomach in obese patients. To evaluate the short-term safety of intravitreous bevacizumab (Avastin) and its effects on visual acuity (VA) and subfoveal choroidal neovascularization (CNV) in patients with neovascular age-related macular degeneration (ARMD). The decrease in AFP mRNA was the result of a decrease in transcription of the AFP gene, as measured by an in vitro nuclear transcription assay. The authors analyze specific features of the reverse development of visual memory disorders associated with various forms of aphasia over rehabilitation training.

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Caregivers also engaged in private prayer and sought spiritual guidance in making decisions in their everyday life more often. This raises the possibility that results of antihypertensive treatment in the elderly could become even better than those already obtained in the SHEP, STOP-Hypertension, and MRC trials. Strategies for controlling intra- and intermicellar packing in block copolymer solutions: illustrating the flexibility of the self-assembly toolbox. This has resulted in a shift from initiatives focused exclusively on analysis of errors to those targeting events linked to harm. Under cell-attached patch conditions, MS-551 reduced the open probability of IK1 channel activity by prolonging the interburst interval without changing either the unitary amplitude or the equilibrium potential.

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Eight university hospitals and two private practice institutions in France. The PDE IV inhibitor rolipram synergistically amplified PDE IV up-regulation by beta 2-receptor agonists.

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An increase in CIC was found in 5 patients and a decrease in 7 patients. Thirty consecutive patients undergoing PDA interruption via the VATS procedure were monitored with an appropriately sized Hewlett-Packard color-Doppler TEE probe. This lipid-modification converts the antibody from a soluble protein into a functional membrane-bound molecule. Within this range lithium produces no clinical or ECG signs of cardiotoxicity, provided the serum Na and K levels remain normal. Despite the persistently small fibril size, increasing numerical density resulted in a gradual increase in fibril area fraction.

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The autogenesis and evolution of the mucosal folds were studied. Effect of human plasma proteins on stabilisation of platelet anti-aggregatory activity of prostacyclin. Clinical characteristics of systemic lupus erythematosus in a hot climate The vegetative state/unresponsive wakefulness syndrome: a systematic review of prevalence studies. Spasmolytic and local anesthetics properties of basic esters of N-alkyl substituted alkoxyphenylcarbamic acids

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The formation of a hypokinetic syndrome of the digestive system under conditions of weightlessness To further determine the role of TGF-beta in Schwann cell proliferation and myelination, we studied Schwann cell proliferation in cultures from mice in which the TGF-beta 1 gene was delected by homologous recombination.

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Myopotential interference with a DDD pacemaker--report of a case. Hydroxyl (OH) distributions and temperature profiles in a premixed propane flame obtained by laser deflection techniques. Our experience of these techniques is discussed and compared with the experiences described in the literature.

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Second, genetic lines selected for psychobiological traits prove useful in establishing relationships between behavioral and neuroendocrine aspects of emotional reactivity. Furthermore, evidence from recent epidemiological studies suggests that low CRF associated risk for HFpEF appears to be modifiable with improvement in CRF. One of the cases illustrates treatment of non-communicating hydrocephalus associated with ventricular tumors by preventive stenting of the cerebrospinal fluid pathways.

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A greenhouse study was conducted to understand the differences in the physiological and transcriptomic responses of TAM 111 and TAM 112 to WD stress. After being asymptomatic for 1 1/2 years, she had several episodes of rest angina culminating in Prinzmetal angina and ventricular fibrillation. The toxins are of current interest in relation to disease and the construction of immunotoxins. We approached the preparation of superlattice films by a layer-by-layer assembly involving Langmuir-Blodgett deposition.

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Randomized trials comparing the open versus the percutaneous technique have limited numbers of patients and follow-up, but preliminary data would suggest that the two techniques compare favorably in appropriately selected patients. Although osteophyte formation was progressive, subchondral bone changes diminished over time. A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes.

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The patients after both the gastric bandaging and the laparoscopic cholecystectomy, demonstrated faster restoration of the physiological stomach contractions frequency in the group with itopride, compared with the placebo group. The fundamental principles of clinical trial design include (1) a priori formulation of a specific research question, (2) precise description of the population to be studied, (3) limitation of the effects of chance by predetermining the study hypothesis and using methods that account for multiple statistical testing, (4) calculation of the sample size necessary to answer the research question, and (5) limitation of the potential bias whenever possible through blinding and random allocation of subjects to treatment and control groups (Table 2). In group B the right saphenous nerve was transected and implanted end-to-side through an epineurial window into the tibial nerve distal to the trifurcation of the sciatic nerve. Biliary hyperplasia and carcinogenesis in chronic liver damage induced in rats by phomopsin. Pathology was consistent with epithelial-myoepithelial carcinoma.

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A homeobox gene involved in node, notochord and neural plate formation of chick embryos. Discovery of Phlebotomus (larroussius) keshishiani, Shchurenkova, 1936 and Phlebotomus (adlerius) angustus Artemiev, 1978 in the foothills of Uzbekistan Immunocytochemical investigation demonstrated the presence of S-100 protein, but the absence of lysozyme in their histiocytic cells, and ultrastructural study revealed Birbeck granules in them. GA-specific T cell lines of the Th2/3 type that inhibit EAE induction in vivo, similarly to those induced by injection of GA, could be isolated from spleens of GA-fed mice and rats.

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The aim of this study was to assess the possible involvement of apoptotic process in the pathogenesis of DCM and myocarditis. Peculiar impressions were formed in the inner retina at the site of the gravitational effect of PFD droplets. maenas to an effective concentration as low as 1.5 microg L(-1) 4-NP resulted in a reduced testis weight, increased liver weight, and altered levels of ecdysone equivalents compared to controls. Addition of TPA to butyric acid or dimethylsulfoxide induced-cells resulted in a transient G1 block in addition to inhibition of differentiation. Ovaries are usually resected during the cytoreductive surgery, since they are common sites for neoplastic implants, and, even when not performed, little is known about the effects of local chemotherapy on female fertility.

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This mode of administration of beta 2-agonists proved extremely useful, either as single therapy or as part of a therapeutic protocol including antibiotics, steroids and theophylline. Beads that are blue in color were unusual in evoking high levels of avoidance in naive chicks and, when used in pretraining in the presence of testosterone, in failing to oppose subsequent training on the blue bead. Isolates of Haemophilus influenzae type b with a distinctive outer-membrane protein subtype, designated 1H, were responsible for 11 of 13 cases of invasive infection in children attending six day-care centers with secondary cases of disease, in comparison to three of 14 cases in children attending 10 centers with single cases and two centers with unrelated cases.

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Cerebral gigantism and primary hypothyroidism: pleiotropy or incidental concurrence. For all these reasons it is recommended to search for findings of HELLP syndrome in patients with hypertensive disorder of pregnancy. The concentrations of IL-6, TT3, TT4, FT4, TSH, urea and creatinine were determined in 13 dogs with canine babesiosis caused by Babesia canis and in 10 healthy dogs. Experimental work in animals showed definite impairment of myocardial function after inferior vena caval ligation, but no changes after clipping.

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Newborn screening for congenital adrenal hyperplasia (CAH) involves measurement of 17alpha-hydroxyprogesterone (17-OHP), usually by immunoassay. However, the specificity of CTL or their precursors that are capable of recognizing HLA-A2 or -B7 was altered after these antigens became associated with the EL4 surface. Existing and projected financial and administrative problems are raised, including a discussion of some of the confusion which has evolved in the provision of related services. One group of animals also had surgical lavage at four and seven days after bacterial inoculation. Hydrocortisone and DOCA substituting therapy demonstrates that these changes are caused by glucocorticoid deficiency.

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Less than a decade has passed since HDAC6 was first identified and regarded as an unusual histone deacetylase harbouring two catalytic domains. The potential of preoperative autologous blood donation to reduce intraoperative homologous blood transfusions in a municipal hospital. These results underscore the importance of understanding regulation of G2/M transition in brain tumor cells. To determine prognosis factors influencing long-term survival after surgical resection for oesophageal adenocarcinoma or squamous cell carcinoma. Proceedings: Clinical significance of carcino-embryonic antigen.

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We describe the case of a female child which suffered from a short rib-polydactyly-syndrome, a localised form of a osteo-chondrodysplasia, and died at the age of nine months as a result of the typical complications of this disease. The clinical experience with other tyrosine kinase inhibitors is limited and imatinib remains the gold standard treatment of locally unresectable/metastatic DFSP. Microscopic examinations revealed slight calcification of elastic fibres in the soft tissues. GENE impedance: a natural process for control of gene expression and the origin of RNA interference. MicroRNA-mediated immune modulation as a therapeutic strategy in host-implant integration.

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Homeostasis changes induced by the action of ethanol on the materno-fetal complex in rats. Effect of epidural analgesia on the glycoregulatory endocrine response to surgery. Structure of the knob protein gene of the Saimiri monkey-adapted Palo Alto strain of Plasmodium falciparum.