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A better understanding of the mechanisms of HIV dissemination, a key step in pathogenesis, would be possible if the cellular pathways of viral dissemination could be followed in simian immunodeficiency virus (SIV)- inoculated monkeys or HIV-infected people. Since several drugs have been demonstrated to have an influence on immune response, the in vitro effects of ketotifen on some immunological parameters were also studied. Prolonged high frequency stimulation has been found to cause depletion of large dense-cored vesicles from glandular nerves. Mechanisms of inactivation of bacteriophage phiX174 and its DNA in aerosols by ozone and ozonized cyclohexene. Desensitization of dietary restraint anxiety and its relationship to weight loss.

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All the patients had drive pathology, and a retarded intellect compared to normal individuals. Furthermore, proliferative responses using WB gave strong and highly significant correlations with a number of important changes in the surface marker phenotype of the lymphocyte populations in the HIV seropositive subjects including CD4, CD8, CD4:CD8 ratio and certain CD8 subsets, whereas strong correlations were not observed with the PBMC. Dietary sources of sodium and eating patterns that offer nutritiously sound approaches to nutrient dense, reduced sodium intake are compared. Relying on phosphoenolpyruvate carboxylase (PEPC) as the primary carboxylase in the mesophyll cells a CO2 pump is established in C4 plants that concentrates CO2 at the site of ribulose 1,5-bisphosphate carboxylase/oxygenase in the bundle-sheath cells.

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Relationship between prescribing and risk of opiate overdose among drug users in and out of maintenance treatment. Pharmacokinetic characterization of menaquinone-4 in dogs by sensitive HPLC determination.

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There was enhancement in free amino acid levels and activity of acid phosphatase by these drugs. The stimulatory effects of L-thyroxine are more pronounced on the weight of the adrenal than of the salivary gland and of the kidney. The effects of cytotoxic (cyclophosphamide, CCNU, GANU), antiinvasive (vincristine, vinblastine) and antimetastatic (ICRF-159, DM-COOK) agents have been compared in mice-bearing P388 and L1210 leukemias, and TLX5 lymphoma. Affinity-purified antigen-specific products produced by T cells share epitopes recognized by heterologous antisera raised against several different antigen-specific products from T cells. The I-V curve of the first component was flat at negative membrane potentials and had a strong outward rectification at positive membrane potentials.

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In 6 patients, erythropoietin (EPO) was also measured before and after the treatment. Preventing smoking during pregnancy: the importance of maternal knowledge of the health hazards and of the treatment options available. Effect of oral propranolol on rest and exercise left ventricular ejection fraction, volumes, and segmental wall motion in patients with angina pectoris. The phosphorylation of the Ser-1200 residue by cyclic AMP-dependent protein kinase transforms ACC from a citrate-independent form to a citrate-dependent form (10, 16). Together, the data show that the Q loop is the central flexion point where the aspect of the drug-binding cavities is coupled to the ATP catalytic cycle.

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Promotion of breast feeding: effect on neonates of change of feeding routine at a maternity unit. Problems connected with alcohol consumption rank in the center of world preoccupation Use of standards of care necessitates charting systems that streamline documentation and avoid unnecessary duplication. Western blot analysis of virion proteins using anti-18R serum detects a 78,000-Da protein, localized in the virus core. Establish that disbalance in the consumption of the food substance and expression of the grease on the composition of the body.

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The use of minisatellite variant repeat-polymerase chain reaction (MVR-PCR) to determine the source of saliva on a used postage stamp. Finally, we present evidence that mAb GK1.5 blocks class II MHC antigen-specific function by blocking class II MHC antigen-specific binding. Prevalence rates of disease and disability increased during the follow-up for both decedents and survivors, with decedents generally having higher rates than survivors. Statistically significant evidence was obtained of the efficacy of UDPG in acute and serious liver disease, and of the greater effectiveness of one of the two doses used.

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The accuracy and reproducibility of the technique make it a useful reference method, commonly employed for studying European variants. Value of cardiac stimulation in the treatment of ventricular tachycardia of the torsade de pointes type According to the World Health Organization (WHO, 2009), every minute, at least one woman dies and 20 are affected by the complications related to pregnancy or childbirth. Our study provides for the first time the information about the complex metabolism of TBBPA in oxic soil and suggests that type II ipso-substitution could play a significant role in the fate of alkylphenol derivatives in the environment. The role of hUCMSCs can be further explored for periodontal regeneration.

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A later survey enables a comparison to be made, with a review of the application in the intervening decade of the earlier recommendations. In efficacy studies, decision aids increased patient knowledge, while communication aids increased patient question-asking and information recall. The results showed that high-need-for-approval subjects revealed themselves more intimately in public than in private conditions wheras low- and moderate-need subjects disclosed more intimately in private than in public. Compulsory postgraduate clinical training in laboratory medicine will start on a national basis in April 2004. She was re-admitted 24 h later, with signs of worsening hemolysis.

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The immunohistologic study of the spleen excised from 7 cases with liver cirrhosis, with the use of the direct immunofluorescence technique, demonstrated the deposits of fibrin in the splenic cords in all cases. The regularity of dental care, preferably provided by one and the same dentist, exerts a positive effect on the incidence of caries and dental health knowledge. Ethical and social issues posed by genetic studies of cardiovascular disease.

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A simple geometric-optical theory predicts impulse broadening in multimode fibers using the far-field power distribution of an incoherently excited waveguide with arbitrary refractive-index profile. However, afterload reduction has no effect on the underlying disease. With light probing forces it appeared that in the nonbrushed group the tips of the probes were located more apically.

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Comodulation masking release for elderly listeners with relatively normal audiograms. To investigate the modulation of the basal blood pressure by neuropeptides, we microinjected these neuropeptides into the rostral ventrolateral medulla of the rat and examined their effects on basal blood pressure.

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Diagnostic problems in cystic fibrosis - specific characteristics of a group of infants and young children diagnosed positive through neonatal screening, in whom cystic fibrosis had not been diagnosed. The usefulness of biological markers in an epidemiologic study depends on the objectives of the study and whether the properties of the markers fulfill the objectives of the study in a feasible and cost-effective manner. Competent persons need to carefully assess how professional and personal time is utilized.

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Certain behavior and attitudes of workers associated with dental care provided in the workplace Our results suggest that electron microscopy may be more sensitive and reliable than light microscopy in confirming the clinical diagnosis of hairy leukoplakia. Smaller neoadjuvant immunotherapy studies with interferon (IFN) alfa and ipilimumab have yielded promising clinical activity and important mechanistic insights and biomarker findings. Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratemporal epilepsy. Effect of repeal of the national maximum speed limit law on occurrence of crashes, injury crashes, and fatal crashes on Utah highways.

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In preceding experiments with nude mice bearing xenotransplanted soft tissue sarcomas after inoculation of cultured sarcoma cells we attained a high percentage of metastatic dissemination by repeated inadequate tumor surgery. Daily counts of admissions to all hospitals for respiratory disease (ICD 9 460-519) were constructed for persons aged 65 years and older in two cities - New Haven, Connecticut and Tacoma, Washington. They grew for weeks as small, unvascularized, three-dimensional aggregates of cells. We treat the scattering pattern as if arising from an equivalent sized Mie sphere, and we attribute the temporal intensity fluctuations to rotational Brownian motion of the whole particle.

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To highlight the risk previously reported in the literature and to reduce the possible dilution effect (due to comparison bias, healthy worker effect), it proved methodologically pivotal to separate exposed and probably unexposed workers (considered as an internal reference group). We here investigated the expression of the antigen (H9/25 Ag) on functional subsets of T and B cells. In magnetic resonance tagging (MRt), tissue elements are magnetically labeled so that their positions can be tracked as a function of time. Early evaluation and treatment are advisable in postmenopausal or senile osteoporosis.

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Two new hepatoprotective stilbene glycosides from Acer mono leaves. Verbascoside (VB), a major bioactive constituent of the Tsoong herb, has attracted a great deal of attention due to its pharmacological properties. A fused silica acousto-optic modulator (AOM) is used in the ultraviolet (UV) spectral region applications while a glass AO deflector (AOD) is used for the visible (VIS) region. Although considerable attention has recently been devoted to explaining why depression is a frequent concomitant of chronic pain, little empirical work has been conducted to test predictions based on these models. Our data reveal a new location for vascular sphincters in pulmonary vessels and, because these novel sphincters are located at the capillary-vein junction, they offer a structural setting for the existence of postcapillary control of blood flow in the pulmonary circulation of mice.

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The lipase exhibited stereoselectivity in the esterification of alcohols such as 2-octanol. Subjects with a T allele of the 5HT2C receptor -759C/T polymorphism may have a lower incidence of weight gain from olanzapine over a 6 week period compared to those with the C allele. Compared to previous methods, this determiniation is easier to perform and more versatile and it prevents rapid epimerization. Lymphocyte responses to both autologous and allogeneic tumor extracts were observed. An atheroma is often associated with saccular aneurysms, but its effect on this pathological process is still unknown.

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Cefotetan versus clindamycin-tobramycin in experimental acute peritonitis in the rat The reaction of 4-hydroxycyclophosphamide (4-hydroxy-CP) with sulfhydryl (SH) compounds was studied, and although the cytotoxic activity was lost a significant stabilization of the alkylating capacity was observed at the same time. Characterization of two new dominant ClC-1 channel mutations associated with myotonia. This result is consistent with the high frequency of zebuine alleles in cattle from East Africa.

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Complex II is a 2:2 9AA/tetranucleotide structure, with two dyes intercalated at the ApG/CpT sites of the duplex. Limb perfusion in the lower limb amputee--a comparative study using a laser Doppler flowmeter and a transcutaneous oxygen electrode. There was a significant increase in the numbers of bacteria isolated and a change in the proportions of the bacteria isolated from ewes after embryo death. Mechanisms for the TMB-8 block of mechanical responses in skeletal muscle. The corrosion was attributed to fabrication of the devices with a corrosion-susceptible stainless steel, AISI type 304.

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Mortality increased significantly when each aerobic organism was inoculated along with either of the Bacteroides species. The acceleration signals received were analysed using the real-time acceleration analysis software, and gait parameters were calculated.

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The ability of percutaneous, image-guided, large-core breast biopsy to provide the correct histologic diagnosis of a breast lesion is equivalent to open surgical biopsy. Anesthesia for thoracoscopic laser ablation of bullae in a patient with severe bullous emphysema Frequently such niches were seen showing complete cellular recovery next to niches with complete aplasia. Azathioprine or chlorambucil were substituted in three cases who developed CP toxicity.

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We evaluated a published model to predict biopsy outcome in men biopsied due to low percentage of free to total prostate-specific antigen. The effect of psychological factors on the childbirth experience via cesarean section

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The presence of P2 in spinal cord as well as in the peripheral nervous system was confirmed. We therefore investigated associations between dose-volume histogram (DVH) parameters of the rectum and the anal canal with fecal continence as measured by an established 10-item questionnaire. X-ray reflectivity (XRR) experiments were also employed to measure the film thickness after PPTA MLD at 145 degrees C and 180 degrees C. Chronic pancreatitis is a progressive, inflammatory disease of pancreas characterized by significant abdominal pain, malabsorption, and diabetes mellitus. Once it was confirmed that magnetic resonance imaging (MRI) including angiography (MRA) could demonstrate intracranial aneurysms, a study was set up to establish whether satisfactory images could be obtained to plan and execute early surgery on ruptured intracranial aneurysms without recourse to intra-arterial digital subtraction angiography (IA.DSA) in the acute phase of the illness.

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Repeated measure ANOVA was applied to examine the effect of mobile phone distraction on selected car-following variables such as driving speed, spacing, and time headway. The combination of laser-line scanning with charge-coupled device detection used in the confocal microscope developed in this work can enable rapid high-resolution sequential imaging, which is ideal for studying photoinduced intracellular fluorescence dynamics. There is a channel that is placed along this axis and appears fully open in both sides. Th17 cells play a crucial role in neutrophilic inflammation and tissue injury in non-cystic fibrosis (non-CF) bronchiectasis.

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Twelve new metabolites were identified by liquid chromatographic/mass spectrometric analysis using fast atom bombardment and packed capillary liquid chromatography columns. We expressed either wild-type alpha2beta1 (alpha2beta1A) or alpha2beta1 with a Y783/795F mutation in the cytoplasmic tail of the beta1 subunit (alpha2beta1Amut) in the beta1-null fibroblastic cell line, GD25.

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The loss of resistance was accompanied by a decrease in the number of cells containing chromosomes with HSRs and an increase in the number with double minutes (DMs). We report two sibs of consanguineous parents with multiple congenital abnormalities which include prenatal and postnatal growth retardation, anterior segment defects of the eye, arachnodactyly with other skeletal abnormalities, congenital heart disease and early lethality. Essential modifications included (1) lowering the redox potential of the medium by adding high levels of ascorbate and (2) modifying the buffer system.

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To determine adverse reactions as a result of pre- and post-exposure rabies vaccination, using the conventional intramuscular, and reduced dose intradermal regimens and purified Vero cell rabies vaccine. gracilis leaf extracts, as well as the antifungal and cytotoxicity properties of plumbagin. Compound heterozygosity for two other mutations, A360P and N393I, was detected in a second family characterized by childhood-onset aggressive course of cardiac and skeletal myopathy.

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In particular, using our Inverse Genomics (Immusol, Inc., San Diego, CA) platform technology, we recently identified Ku80 as an essential co-factor for human immunodeficiency virus replication. AFM-based technologies as the way towards the reverse Avogadro number Augmented uptake of 2-C-14-D-deoxyglucose in reversibly-injured myocardium.

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Anomalous arterial supply to normal Basal segment of the right lower lobe: endovascular treatment with the amplatzer vascular plug. Future studies may uncover a primary site of quinolone immunomodulation, either upstream or at the cell membrane. We aimed to examine the sexually dimorphic immune response following cardioembolic stroke by studying the differential gene expression in peripheral white blood cells. Analysis of an advisor-advisee relationship: an exploratory study of the area of exact and Earth sciences in Brazil. The intergenic region contains poly(A) tracts that appear to be the target of H-NS.

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Peptides from complex II active in reconstitution of succinate-ubiquinone reductase. This phenotype allows the bacteria to avoid reactive oxygen species killing at early stages of growth, thus protecting its genetic material. jecorina, the interaction of Xyr1 and the co-regulators Ace1 and Ace2 in the regulation of transcription of xylanases and cellulases has been studied. It is possible to design a Medicaid HMO that achieves financial savings without reducing services to the most vulnerable patients. The patient characteristics, burn distribution and outcome in 127 patients who had been intentionally assaulted with hot water during a 7 1/2 year period are reported.

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We report a 53 years old Saudi man a known diabetic for more than 15 years. It was found that 4-hydroxycyclophosphamide is bound to thiol groups of bovine serum albumin yielding a rather stable product which could be isolated by column chromatography on Sephadex.

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We report the case of a five-year-old boy with unilateral cervical lymphadenitis who was in good health and showed neither clinical nor laboratory signs of systemic infection. These 3D spheroidal cell cultures are high throughput in vitro model systems that recapitulate some of the chemical and physiological gradients characteristic of tissues. Fusion protein-expressing cells would not plaque influenza virus in the absence of trypsin, nor would influenza virus-infected fusion protein-expressing cells fuse with uninfected cells. The specific glucose consumption and lactate production also indicate that there is a shift to more energy efficient metabolism. If at all possible radical surgery may be performed either as a resection of the tumour and an anastomosis according to Roux-en-Y or a resection of the left or right hepatic lobe together with the obliterated hepatic duct or ducts.

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Noninvasive radionuclide imaging of cells using technetium99m-hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) is a potential diagnostic tool for several applications. Reduction occurred in HDL-C (p less than 0.05) and HDL2-C (p less than 0.01) while HDL3-C remained unchanged, indicating that the effect of isotretinoin is on the HDL2-C subfraction. Heritable factors are evidently involved in prostate cancer (PrCa) carcinogenesis, but currently, genetic markers are not routinely used in screening or diagnostics of the disease. During the examination of the soft tissues of the head and neck also the surface of bones should be each time carefully evaluated.

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The use of homologous fat in obliterating frontal sinus operations has proved to be a satisfactory technique. An attitude scale was administered on a cross-sectional basis to pharmacy students in 3 professional years and alumni 1 year post-graduation.

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The expression of derlin-1 in human breast cancer cell lines was detected by reverse transcription-polymerase chain reaction or Western blot. In animals lacking pha-4 activity, an early step in pharyngeal organogenesis is blocked: no pharyngeal primordium is formed and differentiated pharyngeal cells are absent.

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A yeast two-hybrid screen using ATRAP as bait identified calcium-modulating cyclophilin ligand (CAML) as an ATRAP partner. It is widely recognized that many young people will have experiences with alcohol and with psychoactive recreational drugs before emerging from the adolescent years. In the present case, the surgical control of liver metastases associated with intra-arterial chemotherapy prolonged the quality and length of life with progressive disease extension to other organs. Comparison of external fixation, locking and non-locking palmar plating for unstable distal radius fractures in the elderly.

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These results remained significant after controlling for general intelligence, stress, anxiety and depression. Pre- and postsynaptic effects of muscarinic agonists in the guinea-pig ileum.