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Pharmacists have the unique opportunity and skillset to develop and participate in TOC processes that will enhance medication safety and improve patient care. Haplotype structure of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene and its relationship to serum total bilirubin concentration in a male Korean population. A model is proposed whereby modulation in the production of these factors is determined by the physical presence of stem cells in a proposed cellular milieu, within the adherent layer.

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Lack of improvement in vitamin A status with increased consumption of dark-green leafy vegetables. Higher transferrin-saturation levels were not associated with an increased risk of coronary heart disease or myocardial infarction. A large increase of the photoluminescence yield with temperature is observed in a WSe2 monolayer, indicating the existence of competing radiative channels. The cited data suggest that vitamin C abolishes manifestations of the K-vitamin deficiency affecting the ubiquinone pool and secures its optimal content in the mitochondria. From the relation established between the instantaneous values of So and force it can be concluded that the shape of force increase in anisometric, anisotonic conditions is entirely related to that of MU recruitment, although the absolute value of force depends on both the firing frequency and the number of active MUs.

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Longitudinal changes in standing height and mandibular parameters between the ages of 8 and 17 years. The haemodynamic, renal and endocrine effects of alpha-human atrial natriuretic polypeptide in normotensive people and patients with essential hypertension. Hyperuricemia increased systemic blood pressure, proteinuria, renal dysfunction, vascular disease, and progressive renal scarring in rats. Hyperphosphatemia and metabolic acidosis are frequently encountered in advanced chronic kidney disease (CKD) patients. The human T cell receptor gamma locus, including eleven variable-region, five joining-region, and two constant-region segments, is contained in 160 kilobases.

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The aim of this study was to assess the validity of a walking-stair-climbing test to predict VO2 peak in non-anaemic maintenance dialysis patients. Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage. However, operated rats submitted to the operation and offered a 5 mMol/l drinking solution of crude taurocholic acid during 20 days before submitted to stress had significantly more stress lesions than operated animals with tap water before restraint stress.

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Age and gender specific serum lipid and apolipoprotein fractiles of Finnish children and young adults. All studies were performed using monoclonal antibodies (mAbs) against ovarian carcinoma-associated antigens (OC125, OV-TL3, OV632, 10B, 8C) by 3-step peroxidase-antiperoxidase test. To determine whether patients with COPD would achieve longer exercise duration if randomized to a combination of exercise training plus VF training than either form of training on its own.

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Clinical features of Class II division 2 malocclusion and its orthodontic treatment. In this study, the family history method was used to assess the prevalence of affective illness in first-degree relatives of patients with multiple sclerosis.

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Point mutations revealed that an LI motif within the first region of the cytoplasmic tail and an ML motif in the second region were essential for efficient internalization. Data were collected by questionnaires, anthropometric measurements, and performance on sewing tasks. The parallel glial processes extended in discrete bundles and were always enclosed by a basal lamina.

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All patients were evaluated and managed under a strict multidisciplinary team approach. However, the differences observed were very small and of no clinical significance.

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To evaluate the effect of the Oregon and New Mexico Health Insurance Flexibility and Accountability (HIFA) demonstrations. Effect of the size of the nasotracheal tube on pulmonary ventilation in the course of general anesthesia Of the glutamate agonists tested, only kainate reduced ChAT immunoreactivity significantly in vivo and in vitro. The majority of respondents followed published guidelines, but there was a tendency to overuse azithromycin in certain cases. Patients with reduced fecundability (male factor, minimal endometriosis, or minimal tubal adhesions) may require a longer time to conceive.

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The surface of Staphylococcal cell wall was covered with a fuzzy coat consisting of fine fibers or electron-dence mass. The c-statistics for these models ranged from 0.65 to 0.88 in the development studies, and from 0.63 to 0.80 in the validation studies.

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Differential x-ray diagnosis of atelectasis in the early peroids following operations on the lungs Brown egg laying pullets were transferred from an 8-h photoperiod to an 8-, 10-, 13- or 16-h photoperiod at 6, 9, 12, 15, 18 or 20.3 weeks of age. Hunting and hallucinogens: The use psychoactive and other plants to improve the hunting ability of dogs. However, a number of studies have suggested that normal resting B cells are ineffective as APC, implying that the B cell must leave the resting state before it can interact specifically with a Th cell.

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However, the region between amino acid residues 125 and 127 appears to have a small effect on E1a-mediated repression of the immunoglobulin heavy-chain and polyoma enhancers but has no significant effect on the SV40 enhancer. Both approaches provided excellent access to the anterior inlet of the tumour and exposure of the subclavian vessels, resulting in radical resection of the tumour with concomitant resection of the surrounding anatomical structures, including the chest wall and vessels. The introduction of nonoperative alternatives to elective cholecystectomy in the management of gallstones has resurrected use of oral cholecystography (OCG). The lipid and fatty acid composition of the muscle of the wild Japanese freshwater eel, Anguilla japonica, was analyzed between the initial and terminal stages of spawning migration to clarify the relationship between lipid physiology and maturation. Left atrial damage reduces the electromotive, forces corresponding to the anterolateral portions of the left atrium giving rise to QS or QR slurred P waves with very delayed activation when left portion of interatrial band was damaged.

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The same measurements were performed on the skull films of 100 living children, all less than 3 years old and without clinical history of trauma. Under phosphorus (P) starvation, plants accumulate sugars and starch in their leaves. At present the precise mechanism of action of lithium has not been elucidated. sphaericus, but in B.subtilis it continued into late exponential phase. Among the series of molecules examined, 10l and 18b (YM-228855), combinations of 2-cyanophenyl and 4-methyl-5-isopropylthiazole moieties, showed extremely potent anti-HIV-1 activity.

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A combined 2D/3D evaluation improves sensitivities for polyp detection and reduces inter-individual differences to an insignificant level. Total duodenopancreatectomy as a standard operation in pancreatic cancer

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Measles antibodies and immunoglobulins in sera from patients with subacute sclerosing panencephalitis (SSPE) and from an infected ferret. Tbr-1 and Id-2 expression in the neocortex have discontinuities that define molecularly distinct neocortical areas. Three patients with ALL presented with back pain as the major symptom.

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Significantly higher and more persistent doramectin concentrations were found in the nonparasitized lambs compared to the parasitized animals. This study explored what smartphone health applications (apps) are used by patients, how they learn about health apps, and how information about health apps is shared. We delimited species into biogeographically informative clades, compiled sister-area data, and generated graphic representations of area connections across clades.

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Measurement of beliefs about effectiveness of laparoscopic uterosacral nerve ablation. Two more series impregnated with other silver methods were used as controls.

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Previously, we have shown that stabilization of inhibitor kappaB (IkappaB)-alpha protein following treatment of hepatocytes with transforming growth factor (TGF)-beta1 promoted NF-kappaB repression, which then permitted induction of AP-1/SMAD-mediated liver cell death. cereus plcR gene active the expression of sphingomyelinase gene, but did not activate expression of hemolysin genes of B. Interaction between heparanase and TFPI was evident by co-immunoprecipitation.

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Placental tissue expressed a single 2.3 kb preproendothelin messenger ribonucleic acid and produced comparable amounts of endothelin 3, Big endothelin 1, and endothelin 1 and a minor quantity of endothelin 2. Nanoscale structure and superhydrophobicity of sp(2)-bonded boron nitride aerogels. Impact of CNG implementation on PAHs concentration in the ambient air of Delhi: a comparative assessment of pre- and post-CNG scenario.

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Vitreomacular traction syndrome is a clinical entity characterized by partial posterior vitreous detachment in combination with persistent macular adherence. Neural correlates of the reverse Simon effect in the Hedge and Marsh task. Problems with definition, study design and validity of the diagnosis prevented comprehensive understanding whether postpartum depression is a distinct subtype of endogenous depression. The diverse developmental patterns of obesogenic behaviors during childhood and adolescence can be better understood by using new analytic approaches to assess the heterogeneity in variation during growth and development and to map the clustering of behavior patterns. Obesity is associated with a low-grade inflammatory state, which may predispose obese patients to such complications.

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The neuronal organization of the lateral (L) and basolateral (BL) amygdaloid nuclei was studied in the rat by using Golgi techniques. Thirty-two patients needed bladder catheterization because of acute urinary retention. By using a commercially available autotransfusion device, fat can be aspirated and reinfused into the venous circulation. Although the model represents a significant improvement compared with earlier attempts, a considerable percentage of the variation in NGF number between women cannot be explained by age alone. We have now established transgenic Drosophila strains that allow for individual overexpression of all known mouse Dnmts.

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Actual intubation difficulty using RSI was significantly less than the anticipated intubation difficulty without RSI. An estimated 3217 YLD were lost due to periodontal disease, with a rate of 0.2/1000 for both sexes. An inverse relation between the expression of p16/CDKN2 and Rb has been noted in many tumours, but has not yet been determined in oesophageal squamous carcinoma. Expression of HAS1 transcripts was not detected under any condition in these cells.

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Multimodal monitoring: head injury management using SjvO2 and LICOX. 7-Methylguanosine at the anticodon wobble position of squid mitochondrial tRNA(Ser)GCU: molecular basis for assignment of AGA/AGG codons as serine in invertebrate mitochondria. Report of cases with reference to the literature on chronic constipation Diagnosis is grounded on the finding of the enlarged orifice of the gland and its suppuration.

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injection of Gd DOTA are especially helpful for the diagnosis and preoperative staging of cervico-thoracic lymphangiomas in children. The effect of PGE2 in exercise induced asthma has also been studied. Systemic hemodynamics and renal function in cirrhotic patients during plasma volume expansion. Our results provide a useful gene signature profile describing the factors underlying the metastasis of HNSCC to cervical lymph nodes, which may be beneficial for the treatment of HNSCC metastasis.

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The survival advantage related to the stimulated pattern was observed primarily among patients with advanced disease. The presynaptic terminals contained 80 to 130 nm granular vesicles and 30 to 40 nm clear vesicles. While the majority of telomeres revealed constrained diffusive movement, individual telomeres in a human cell nucleus showed significant directional movements. Current and future trials are exploring the use of these agents in combination with each other and with standard chemotherapy. Recurrent angina 1 year later occurred following closure of the left internal thoracic artery graft.

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Intravesical instillaton of adriamycin: treatment of patients with difficulties to retain the instilled liquid. The significance of CT lies in the exact documentation of the localization and extent of the lesions and in evaluation. Synaptic responses of single neurons to stimulation of the caudal and rostral SPs before and after electrolytic lesion of the intermediate SP were recorded 5-17 mm caudal to the caudal SP. The relevance for the immunological responsiveness of an animal of selective entry to and egress from the lymph of antigenically reactive cells. Of the 30 infants included in the study, 5 infants had a grade III or IV/VI intraventricular hemorrhage.

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However, most patients perceive them favourably and many would consider owning one. Intravenous injection of narcotic stimulants affects many cellular functions relevant for the pathophysiological mechanisms of heart failure. Computer simulation of in vivo steroid binding by plasma proteins in the presence of interfering drugs. This concentration of dipyridamole could be obtained by the intravenous administration without severe adverse effects. Differential membrane-regulation mechanisms, dependent on the extracellular potassium concentrations, may account for the increased susceptibility to antiarrhythmia agents in the late postinfarction phase.

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Although the resulting tomographic images provide valuable information, their resolution declines at axial distances beyond about 1 microm from the focal plane. An increasing time interval from weaning to hair sample collection was not associated with any detectable decrease in mercury concentrations. Indeed, an oxidative agent reproduces the H2O2-evoked response while reducing agents prevent the effect of H2O2. Trimethoprim-sulfamethoxazole (TMP-SMZ) is effective in both the treatment and the prevention of Pneumocystis carinii pneumonitis. Borrelia burgdorferi in an urban environment: white-tailed deer with infected ticks and antibodies.

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The gas tensions were measured by a mass spectrometer via a special catheter inlet system. reesei, in the production of heterologous proteins is becoming more successful. B Cell Production of Both OPG and RANKL is Significantly Increased in Aged Mice. The endothelium was negative in the midcycle and positive early and late in the cycle for FcRI and FcRIII, although weak for FcRIII late in the cycle.

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Effect of cyclooxygenase-2-specific inhibitors on postoperative analgesia after major open abdominal surgery. Endogenous D-factor activity partially mediates the toxic but not the therapeutic effects of tumor necrosis factor.

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Cumulative prevalence of urinary characteristics in very old people. Towards a better understanding of honeycomb alternating magnetic networks. The concentration of plasma vitamin B12 bound to transcobalamin II was measured by two methods: QUSO and Heparin Sepharose (HS). Concurrent meningioma and malignant melanoma tumor of the associated choroid (apropos of a case)

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Plasmids were constructed to direct synthesis of the human interferons IFN-alpha 1, IFN-alpha 2, and IFN-gamma in the yeast Saccharomyces cerevisiae. An 18-month followup of students biologically at risk for psychiatric problems. The effect of celiprolol at a daily dosage of 300 mg (19 patients) was compared with that of propranolol at a daily dosage of 120 mg (14 patients) on peripheral blood flow of the calf and foot in a randomized double-blind trial. Results indicated that CBA mice began to produce minimal amounts of anti-dextran antibodies between 15 and 21 days of age, and the development continued progressively until peak levels were reached at 90 days of age. The choice of surgical methodology in gunshot injury of the colon

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The treatment landscape in oncology is quickly evolving with the advent of ICIs. Health status after critical illness: beyond descriptive studies. Both random-primed amplification and degenerate oligonucleotide-primed amplification approaches were tested using varying amounts of fresh and paraffin-extracted normal and breast tumor input DNAs. Features of the functional brain disorders in diabetes are discussed.